Rights statement: c 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
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Available under license: CC BY
Final published version
Licence: CC BY
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Williams syndrome
T2 - a surprising deficit in oromotor praxis in a population with proficient language production
AU - Krishnan, Saloni
AU - Bergstroem, Lina
AU - Alcock, Katherine J.
AU - Dick, Frederic
AU - Karmiloff-Smith, Annette
N1 - Date of Acceptance: 25/11/2014 c 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
PY - 2015/1
Y1 - 2015/1
N2 - Williams Syndrome (WS) is a neurodevelopmental disorder of known genetic origin, characterized by serious delays in language onset yet relatively verbose, intelligible and fluent speech in late childhood and adulthood. How do motor abilities relate to language in this group? We investigated planning and co-ordination of the movement of the speech articulators (oromotor praxis) in 28 fluent-speaking individuals with WS, aged between 12 and 30 years. Results indicate that, despite their fluent language, oromotor praxis was impaired in WS relative to two groups of typically-developing children, matched on either vocabulary or visuospatial ability. These findings suggest that the ability to plan, co-ordinate and execute complex sensorimotor movements contribute to an explanation of the delay in expressive language early in development in this neurodevelopmental disorder. In the discussion, we turn to more general issues of how individual variation in oromotor praxis may account for differences in speech/language production abilities across developmental language disorders. (c) 2014 The Authors. Published by Elsevier Ltd.
AB - Williams Syndrome (WS) is a neurodevelopmental disorder of known genetic origin, characterized by serious delays in language onset yet relatively verbose, intelligible and fluent speech in late childhood and adulthood. How do motor abilities relate to language in this group? We investigated planning and co-ordination of the movement of the speech articulators (oromotor praxis) in 28 fluent-speaking individuals with WS, aged between 12 and 30 years. Results indicate that, despite their fluent language, oromotor praxis was impaired in WS relative to two groups of typically-developing children, matched on either vocabulary or visuospatial ability. These findings suggest that the ability to plan, co-ordinate and execute complex sensorimotor movements contribute to an explanation of the delay in expressive language early in development in this neurodevelopmental disorder. In the discussion, we turn to more general issues of how individual variation in oromotor praxis may account for differences in speech/language production abilities across developmental language disorders. (c) 2014 The Authors. Published by Elsevier Ltd.
KW - Orofacial movements
KW - Sequencing
KW - Motor ability
KW - Speech motor control
KW - Williams syndrome
KW - SHORT-TERM-MEMORY
KW - INHERITED SPEECH
KW - DOWNS-SYNDROME
KW - MOTOR SKILL
KW - ORAL-MOTOR
KW - CHILDREN
KW - IMPAIRMENT
KW - ABILITIES
KW - BRAIN
KW - PHENOTYPE
U2 - 10.1016/j.neuropsychologia.2014.11.032
DO - 10.1016/j.neuropsychologia.2014.11.032
M3 - Journal article
VL - 67
SP - 82
EP - 90
JO - Neuropsychologia
JF - Neuropsychologia
SN - 0028-3932
ER -