Innate immune recognition of intracellular DNA as 'stranger' and 'danger' signal - Research Portal | Lancaster University

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Innate immune recognition of intracellular DNA as 'stranger' and 'danger' signal

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/18

Funding

European Commission: £51,086.18

Unterholzner, Leonie (Principal Investigator)

Research outputs

IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes
Research output: Contribution to Journal/Magazine › Journal article › peer-review
cGAS-independent STING activation in response to DNA damage
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Non-canonical activation of the DNA sensing adaptor STING by ATM and IFI16 mediates NF-κB signalling after nuclear DNA damage
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Camouflage and interception: How pathogens evade detection by intracellular nucleic acid sensors
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Beyond sensing DNA: A role for cGAS in the detection of extracellular cyclic di-nucleotides
Research output: Contribution to Journal/Magazine › Journal article