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Regulation of DNA replication by diadenosine nucleotides after DNA damage

Project: Research

Description

NWCR Post-Doctoral research fellowship

Status	Finished
Effective start/end date	1/10/13 → 30/09/16

Nigel Jones, Dr (Principal Investigator)
Copeland, Nikki (Co-Investigator)
Sandy McLennan, Prof (Co-Investigator)

Research outputs

Diadenosine 5′, 5′′′-P1,P4-tetraphosphate (Ap4A) is synthesized in response to DNA damage and inhibits the initiation of DNA replication.
Research output: Contribution to Journal/Magazine › Journal article › peer-review
NUDT2 disruption elevates diadenosine tetraphosphate (Ap4A) and down-regulates immune response and cancer promotion genes
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Re-evaluation of Diadenosine Tetraphosphate (Ap4A) From a Stress Metabolite to Bona Fide Secondary Messenger
Research output: Contribution to Journal/Magazine › Book/Film/Article review › peer-review