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Results for Enzyme Inhibitors

Publications & Outputs

  1. GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease

    Gao, C., Hölscher, C., Liu, Y. & Li, L., 02/2012, In: Reviews in the Neurosciences. 23, 1, p. 1-11 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei

    Abdelwahab, N. Z., Urbaniak, M. D., Ferguson, M. A. J. & Crossman, A. T., 1/05/2011, In: Carbohydrate Research. 346, 6, p. 708-714 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors: toward the development of novel therapies for African sleeping sickness

    Durrant, J. D., Urbaniak, M. D., Ferguson, M. A. J. & McCammon, J. A., 8/07/2010, In: Journal of Medicinal Chemistry. 53, 13, p. 5025-5032 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10

    Parkin, E. & Harris, B., 03/2009, In: Journal of Neurochemistry. 108, 6, p. 1464-1479 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues

    Urbaniak, M. D., Yashunsky, D. V., Crossman, A., Nikolaev, A. V. & Ferguson, M. A. J., 17/10/2008, In: ACS Chemical Biology. 3, 10, p. 625-634 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis

    Crossman, A. T., Urbaniak, M. D. & Ferguson, M. A. J., 7/07/2008, In: Carbohydrate Research. 343, 9, p. 1478-1481 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness

    Urbaniak, M. D., Tabudravu, J. N., Msaki, A., Matera, K. M., Brenk, R., Jaspars, M. & Ferguson, M. A. J., 15/11/2006, In: Bioorganic and Medicinal Chemistry Letters. 16, 22, p. 5744-5747 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Multiple responses to EGF receptor activation and their abrogation by a specific EGF receptor tyrosine kinase inhibitor

    Harper, M. E., Goddard, L., Glynne-Jones, E., Assender, J., Dutkowski, C. M., Barrow, D., Dewhurst, O. L., Wakeling, A. E. & Nicholson, R. I., 15/06/2002, In: The Prostate. 52, 1, p. 59-68 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Carboxyl-methylation of prenylated calmodulin CaM53 is required for efficient plasma membrane targeting of the protein

    Rodríguez-Concepción, M., Toledo-Ortiz, G., Yalovsky, S., Caldelari, D. & Gruissem, W., 12/2000, In: The Plant Journal. 24, 6, p. 775-784 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Endogenously inhibited protein kinase C in transgenic Drosophila embryonic neuroblasts down regulates the outgrowth of type I and II processes of cultured mature neurons

    Broughton, S. J., Kane, N. S., Arthur, B., Yoder, M., Greenspan, R. J. & Robichon, A., 15/03/1996, In: Journal of Cellular Biochemistry. 60, 4, p. 584-599 16 p.

    Research output: Contribution to journalJournal articlepeer-review