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Results for Nuclear Proteins

Publications & Outputs

  1. Structural mechanism of DNA recognition by the p204 HIN domain

    Fan, X., Jiang, J., Zhao, D., Chen, F., Ma, H., Smith, P., Unterholzner, L., Xiao, T. S. & Jin, T., 18/03/2021, In: Nucleic Acids Research. 49, 5, p. 2959-2972 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Structural basis of PROTAC cooperative recognition for selective protein degradation

    Gadd, M. S., Testa, A., Lucas, X., Chan, K-H., Chen, W., Lamont, D. J., Zengerle, M. & Ciulli, A., 31/05/2017, In: Nature Chemical Biology. 13, 5, p. 514-521 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. The HY5-PIF regulatory module coordinates light and temperature control of photosynthetic gene transcription

    Toledo-Ortiz, G., Johansson, H., Lee, K. P., Bou-Torrent, J., Stewart, K., Steel, G., Rodríguez-Concepción, M. & Halliday, K. J., 12/06/2014, In: PLoS Genetics. 10, 6, 14 p., e1004416.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1

    Xu, W., Cohen-Woods, S., Chen, Q., Noor, A., Knight, J., Hosang, G., Parikh, S. V., De Luca, V., Tozzi, F., Muglia, P., Forte, J., McQuillin, A., Hu, P., Gurling, H. M. D., Kennedy, J. L., McGuffin, P., Farmer, A., Strauss, J. & Vincent, J. B., 4/01/2014, In: Journal of Medical Genetics. 15, 13 p., 2.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

    Horan, K. A., Hansen, K., Jakobsen, M. R., Holm, C. K., Søby, S., Unterholzner, L., Thompson, M., West, J. A., Iversen, M. B., Rasmussen, S. B., Ellermann-Eriksen, S., Kurt-Jones, E., Landolfo, S., Damania, B., Melchjorsen, J., Bowie, A. G., Fitzgerald, K. A. & Paludan, S. R., 1/03/2013, In: Journal of Immunology. 190, 5, p. 2311-2319 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor

    Jin, T., Perry, A., Jiang, J., Smith, P., Curry, J. A., Unterholzner, L., Jiang, Z., Horvath, G., Rathinam, V. A., Johnstone, R. W., Hornung, V., Latz, E., Bowie, A. G., Fitzgerald, K. A. & Xiao, T. S., 20/04/2012, In: Immunity. 36, 4, p. 561-571 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. IFI16 is an innate immune sensor for intracellular DNA

    Unterholzner, L., Keating, S. E., Baran, M., Horan, K. A., Jensen, S. B., Sharma, S., Sirois, C. M., Jin, T., Latz, E., Xiao, T. S., Fitzgerald, K. A., Paludan, S. R. & Bowie, A. G., 11/2010, In: Nature Immunology. 11, 11, p. 997-1004 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro

    Copeland, N. A., Sercombe, H. E., Ainscough, J. F. X. & Coverley, D., 1/04/2010, In: Journal of Cell Science. 123, 7, p. 1108-1115 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization

    Fielding, A. B., Dobreva, I., McDonald, P. C., Foster, L. J. & Dedhar, S., 25/02/2008, In: Journal of Cell Biology. 180, 4, p. 681-9 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease

    Garcia-Barcelo, M., Ganster, R. W., Lui, V. C. H., Leon, T. Y. Y., So, M-T., Lau, A. M. F., Fu, M., Sham, M-H., Knight, J., Zannini, M. S., Sham, P. C. & Tam, P. K. H., 15/01/2005, In: Human Molecular Genetics. 14, 2, p. 191-204 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex

    Bono, F., Ebert, J., Unterholzner, L., Güttler, T., Izaurralde, E. & Conti, E., 03/2004, In: EMBO Reports. 5, 3, p. 304-310 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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