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Medical and Pharmaceutical Statistics Research Unit

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  1. Published

    R software to accompany "Bayesian methods for the design and interpretation of clinical trials in very rare diseases".

    Hampson, L. & Whitehead, J., 2014

    Research output: Exhibits, objects and web-based outputs › Software

  2. Published

    Recording lectures as a service in a service course.

    Jaki, T., 11/2009, In: Journal of Statistics Education. 17, 3

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Recovering Independent Associations in Genetics: A Comparison

    Sperrin, M. & Jaki, T., 08/2012, In: Journal of Computational Biology. 19, 8, p. 978–987 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Recurrent events modelling of haemophilia bleeding events

    Titman, A., Wolfsegger, M. J. & Jaki, T., 1/03/2021, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 70, 2, p. 351-371 21 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Sample size considerations in active-control non-inferiority trials with binary data based on the odds ratio

    Siqueira, A. L., Todd, S. & Whitehead, A., 08/2015, In: Statistical Methods in Medical Research. 24, 4, p. 453-461 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Sample size reassessment and hypothesis testing in adaptive survival trials

    Magirr, D., Jaki, T. F., Koenig, F. & Posch, M., 10/02/2016, In: PLoS ONE. 11, 2, 14 p., e0146465.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Sequential genome-wide association studies for monitoring adverse events in clinical evaluation of new drugs.

    Whitehead, J., Kelly, P. J., Stallard, N., Zhou, Y. & Bowman, C., 30/09/2006, In: Statistics in Medicine. 25, 18, p. 3081-3092 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Sequential methods for random-effects meta-analysis

    Higgins, J. P. T., Whitehead, A. & Simmonds, M., 30/04/2011, In: Statistics in Medicine. 30, 9, p. 903-921 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Sequentially testing for a gene-drug interaction in a genomewide analysis.

    Kelly, P., Zhou, Y., Whitehead, J., Stallard, N. & Bowman, C., 20/05/2008, In: Statistics in Medicine. 27, 11, p. 2022-2034 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Simultaneous confidence intervals by iteratively adjusted alpha for relative effects in the one-way layout.

    Wolfsegger, M. J. & Jaki, T., 2006, In: Statistics and Computing. 16, 1, p. 15-23 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Simultaneous confidence regions for multivariate bioequivalence

    Pallmann, P. S. & Jaki, T. F., 20/12/2017, In: Statistics in Medicine. 36, 29, p. 4585-4603 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Spatial and temporal patterns in antimicrobial resistance of Salmonella Typhimurium amongst cattle in England and Wales

    Cox, R., Su, T-L., Clough, H., Woodward, MJ. & Sherlock, C., 2012, In: Epidemiology and Infection. p. 1-12 12 p., PMID: 22214772.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Statistical approaches for the determination of cut points in anti-drug antibody bioassays

    Schaarschmidt, F., Hofmann, M., Jaki, T., Gruen, B. & Hothorn, L. A., 03/2015, In: Journal of Immunological Methods. 418, p. 84-100 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Statistical evaluation of toxicological assays: Dunnett or Williams test? − take both

    Jaki, T. & Hothorn, L. A., 11/2013, In: Archives of Toxicology. 87, 11, p. 1901-1910 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Statistical evaluation of toxicological assays with zero or near-to-zero proportions or counts in the concurrent negative control group: a tutorial

    Jaki, T., Kitsche, A. & Hothorn, L. A., 2014, In: JP Journal of Biostatistics. 11, 1, p. 1-32 32 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Strategies to prevent falls and fractures in hospitals and care homes and effect of cognitive impairment: systematic review and meta- analysis.

    Oliver, D., Connelly, J. B., Victor, C. R. & Whitehead, A., 13/01/2007, In: BMJ. 334, 7584, p. 82-85 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Study to evaluate the optimal dose of remifentanil required to ensure apnea during magnetic resonance imaging of the heart under general anesthesia

    Arnold, P., Sanaulla, S., Hampson, L. V., Davis, A., Tan, J., Cowen, R., Kaleem, M., Williams, A., Wadsworth, I. & Jaki, T., 31/05/2021, In: Paediatric Anesthesia. 31, 5, p. 548-556 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Symmetric maximum kernel likelihood estimation.

    Jaki, T. & West, R. W., 02/2011, In: Journal of Statistical Computation and Simulation. 81, 2, p. 193-206 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of Telmisartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on combination antiretroviral therapy

    Pushpakom, S. P., Taylor, C., Kolamunnage-Dona, R., Spowart, C., Vora, J., Garcıa-Finana, M., Kemp, G. J., Whitehead, J., Jaki, T., Khoo, S., Williamson, P. & Pirmohamed, M., 15/10/2015, In: BMJ Open. 5, 10, 13 p., e009566.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    The effect of selective decontamination of the digestive tract on mortality in multiple trauma patients: a multicenter randomized controlled trial.

    The Working Group on Selective Decontamination of the Digestive Tract, 02/2007, In: Intensive Care Medicine. 33, 2, p. 261-270 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    The R package MAMS for designing multi-arm multi-stage clinical trials

    Jaki, T. F., Pallmann, P. S. & Magirr, D., 31/01/2019, In: Journal of Statistical Software. 88, 4, 25 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    The sequential analysis of repeated binary responses: a score test for the case of three time points.

    Sooriyarachchi, M. R., Whitehead, J., Whitehead, A. & Bolland, K., 15/07/2006, In: Statistics in Medicine. 25, 13, p. 2196-2214 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    'Threshold crossing': a useful way to establish the counterfactual in clinical trials?

    Eichler, H-G., Bloechl-Daum, B., Bauer, P., Bretz, F., Brown, J., Hampson, L. V., Honig, P., Krams, M., Leufkens, H., Lim, R., Lumpkin, M., Murphy, M., Pignatti, F., Posch, M., Schneeweiss, S., Trusheim, M. & Koenig, F., 12/2016, In: Clinical Pharmacology & Therapeutics. 100, p. 699-712 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Tilting the lasso by knowledge-based post-processing

    Tharmaratnam, K., Sperrin, M., Jaki, T. F., Reppe, S. & Frigessi, A., 2/09/2016, In: BMC Bioinformatics. 17, 9 p., 344.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Trial design for evaluating novel treatments during an outbreak of an infectious disease

    Whitehead, J. R., Olliaro, P., Lang, T. & Horby, P. W., 02/2016, In: Clinical Trials. 13, 1, p. 31-38 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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