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Medical and Pharmaceutical Statistics Research Unit

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  1. Chapter (peer-reviewed)
  2. Published

    Designing multi-arm multi-stage clinical studies

    Jaki, T., 2014, Developments in statistical evaluation of clinical trials. van Montfort, K., Oud, J. & Ghidey, W. (eds.). Berlin: Springer, p. 51-69 19 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter (peer-reviewed) › peer-review

  3. Software
  4. Published

    R software to accompany "Bayesian methods for the design and interpretation of clinical trials in very rare diseases".

    Hampson, L. & Whitehead, J., 2014

    Research output: Exhibits, objects and web-based outputs › Software

  5. Published

    C Code to design error spending tests for delayed responses

    Hampson, L. & Jennison, C., 3/09/2012

    Research output: Exhibits, objects and web-based outputs › Software

  6. Journal article
  7. Published

    A novel statistical test for treatment differences in clinical trials using a response‐adaptive forward‐looking Gittins Index Rule

    Barnett, H. Y., Villar, S. S., Geys, H. & Jaki, T., 31/03/2023, In: Biometrics. 79, 1, p. 86-97 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Point estimation for adaptive trial designs I: A methodological review

    Robertson, D. S., Choodari‐Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. & Jaki, T., 30/01/2023, In: Statistics in Medicine. 42, 2, p. 122-145 24 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Dose finding studies for therapies with late‐onset toxicities: A comparison study of designs

    Barnett, H., Boix, O., Kontos, D. & Jaki, T., 30/12/2022, In: Statistics in Medicine. 41, 30, p. 5767-5788 22 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Practical implementation of the partial ordering continual reassessment method in a Phase I combination‐schedule dose‐finding trial

    Mozgunov, P., Jaki, T., Gounaris, I., Goddemeier, T., Victor, A. & Grinberg, M., 30/12/2022, In: Stat. Med.. 41, 30, p. 5789-5809 21 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. E-pub ahead of print

    Proposing a Core Outcome Set for Physical Activity and Exercise Interventions in People With Rare Neurological Conditions

    Ramdharry, G., Buscemi, V., Boaz, A., Dawes, H., Jaki, T., Jones, F., Marsden, J., Paul, L., Playle, R., Randell, E., Robling, M., Rochester, L. & Busse, M., 21/10/2021, (E-pub ahead of print) In: Frontiers in Rehabilitation Sciences. 2, 13 p., 705474.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Study to evaluate the optimal dose of remifentanil required to ensure apnea during magnetic resonance imaging of the heart under general anesthesia

    Arnold, P., Sanaulla, S., Hampson, L. V., Davis, A., Tan, J., Cowen, R., Kaleem, M., Williams, A., Wadsworth, I. & Jaki, T., 31/05/2021, In: Paediatric Anesthesia. 31, 5, p. 548-556 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Recurrent events modelling of haemophilia bleeding events

    Titman, A., Wolfsegger, M. J. & Jaki, T., 1/03/2021, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 70, 2, p. 351-371 21 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Exposure–response modelling approaches for determining optimal dosing rules in children

    Wadsworth, I., Hampson, L. V., Bornkamp, B. & Jaki, T., 1/09/2020, In: Statistical Methods in Medical Research. 29, 9, p. 2583-2602 20 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Estimation of treatment effects following a sequential trial of multiple treatments

    Whitehead, J., Desai, Y. & Jaki, T., 20/05/2020, In: Statistics in Medicine. 39, 11, p. 1593-1609 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    A quantitative framework to inform extrapolation decisions in children

    Wadsworth, I., Hampson, L. V., Jaki, T., Sills, G. J., Marson, A. G. & Appleton, R., 1/02/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 2, p. 515-534 20 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    The R package MAMS for designing multi-arm multi-stage clinical trials

    Jaki, T. F., Pallmann, P. S. & Magirr, D., 31/01/2019, In: Journal of Statistical Software. 88, 4, 25 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Model selection based on combined penalties for biomarker identification

    Vradi, E., Brannath, W., Jaki, T. & Vonk, R., 4/07/2018, In: Journal of Biopharmaceutical Statistics. 28, 4, p. 735-749 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Extrapolation of efficacy and other data to support the development of new medicines for children: a systematic review of methods

    Wadsworth, I., Hampson, L. V. & Jaki, T. F., 1/02/2018, In: Statistical Methods in Medical Research. 27, 2, p. 398-413 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    A review of statistical updating methods for clinical prediction models

    Su, T-L., Jaki, T. F., Hickey, G., Buchan, I. & Sperrin, M., 1/01/2018, In: Statistical Methods in Medical Research. 27, 1, p. 185-197 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Identification of Predicted Individual Treatment Effects (PITE) in randomized clinical trials

    Lamont, A. E., Lyons, M., Jaki, T. F., Stuart, E. A., Feaster, D., Ishwaran, H., Tharmaratnam, K. & Van Horn, M. L., 1/01/2018, In: Statistical Methods in Medical Research. 27, 1, p. 142-157 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Simultaneous confidence regions for multivariate bioequivalence

    Pallmann, P. S. & Jaki, T. F., 20/12/2017, In: Statistics in Medicine. 36, 29, p. 4585-4603 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Factorial versus multi-arm multi-stage designs for clinical trials with multiple treatments

    Jaki, T. F. & Vasileiou, D., 20/02/2017, In: Statistics in Medicine. 36, 4, p. 563-580 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Bayesian survival analysis in clinical trials: what methods are used in practice?

    Brard, C., Le Teuff, G., Le Deley, M-C. & Hampson, L. V., 1/02/2017, In: Clinical Trials. 14, 1, p. 78-87 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    'Threshold crossing': a useful way to establish the counterfactual in clinical trials?

    Eichler, H-G., Bloechl-Daum, B., Bauer, P., Bretz, F., Brown, J., Hampson, L. V., Honig, P., Krams, M., Leufkens, H., Lim, R., Lumpkin, M., Murphy, M., Pignatti, F., Posch, M., Schneeweiss, S., Trusheim, M. & Koenig, F., 12/2016, In: Clinical Pharmacology & Therapeutics. 100, p. 699-712 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. Published

    Clinical drug development in epilepsy revisited: a proposal for a new paradigm streamlined using extrapolation

    Wadsworth, I., Jaki, T. F., Sills, G. J., Appleton, R., Cross, J. H., Marson, A. G., Martland, T., McLellan, A., Smith, P. E. M., Pellock, J. M. & Hampson, L. V., 11/2016, In: CNS Drugs. 30, 11, p. 1011-1017 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  27. Published

    A false sense of security? can tiered approach be trusted to accurately classify immunogenicity samples?

    Jaki, T. F., Allacher, P. & Horling, F., 5/09/2016, In: Journal of Pharmaceutical and Biomedical Analysis. 128, p. 166-173 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. Published

    Tilting the lasso by knowledge-based post-processing

    Tharmaratnam, K., Sperrin, M., Jaki, T. F., Reppe, S. & Frigessi, A., 2/09/2016, In: BMC Bioinformatics. 17, 9 p., 344.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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