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Medical and Social Statistics

  1. 2023
  2. Published

    Using biomarkers to allocate patients in a response-adaptive clinical trial

    Jackson, H., Bowen, S. & Jaki, T., 2/12/2023, In: Communications in Statistics: Simulation and Computation. 52, 12, p. 5946-5965 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Identifying prodromal symptoms at high specificity for Parkinson’s disease

    Jackson, H., Anzures-Cabrera, J., Simuni, T., Postuma, R. B., Marek, K. & Pagano, G., 22/09/2023, In: Frontiers in Aging Neuroscience. 15, 1232387.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. E-pub ahead of print

    A comparison of Bayesian information borrowing methods in basket trials and a novel proposal of modified exchangeability‐nonexchangeability method

    Daniells, L., Mozgunov, P., Bedding, A. & Jaki, T., 23/08/2023, (E-pub ahead of print) In: Statistics in Medicine.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    A Bayesian multi‐arm multi‐stage clinical trial design incorporating information about treatment ordering

    Serra, A., Mozgunov, P. & Jaki, T., 20/07/2023, In: Statistics in Medicine. 42, 16, p. 2841-2854 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    An alternative to traditional sample size determination for small patient populations

    Jackson, H. & Jaki, T., 3/07/2023, In: Statistics in Biopharmaceutical Research. 15, 3, p. 596-607 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. E-pub ahead of print

    A Spline Function Method for Modelling and Generating a Nonhomogeneous Poisson Process

    Morgan, L., Nelson, B., Titman, A. & Worthington, D., 19/06/2023, (E-pub ahead of print) In: Journal of Simulation. 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Point estimation for adaptive trial designs I: A methodological review

    Robertson, D. S., Choodari‐Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. & Jaki, T., 30/01/2023, In: Statistics in Medicine. 42, 2, p. 122-145 24 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Input Uncertainty Quantification for Quantiles

    Parmar, D., Morgan, L., Titman, A., Sanchez, S. & Williams, R., 23/01/2023, 2022 Winter Simulation Conference (WSC). Feng, B., Pedrielli, G., Peng, Y., Shashaani, S., Song, E., Corlu, C. G., Lee, L. H., Chew, E. P., Roeder, T. & Lendermann, P. (eds.). IEEE, p. 97-108 12 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  10. Published

    Confidence Intervals for the Treatment Effects in Adaptive Enrichment Designs

    Zhu, J., 2023, Lancaster University. 118 p.

    Research output: ThesisDoctoral Thesis

  11. Published

    Rare Disease Trials: Beyond the Randomised Controlled Trial

    Jackson, H., 2023, Lancaster University. 237 p.

    Research output: ThesisDoctoral Thesis

  12. 2022
  13. Published

    Penalty shootouts: Are estimates on the spot?

    Jackson, J., 31/12/2022, In: Significance. 19, 6, p. 10-13 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Dose finding studies for therapies with late‐onset toxicities: A comparison study of designs

    Barnett, H., Boix, O., Kontos, D. & Jaki, T., 30/12/2022, In: Statistics in Medicine. 41, 30, p. 5767-5788 22 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Practical implementation of the partial ordering continual reassessment method in a Phase I combination‐schedule dose‐finding trial

    Mozgunov, P., Jaki, T., Gounaris, I., Goddemeier, T., Victor, A. & Grinberg, M., 30/12/2022, In: Stat. Med.. 41, 30, p. 5789-5809 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Using saturated count models for user-friendly synthesis of large confidential administrative databases

    Jackson, J., Mitra, R., Francis, B. & Dove, I., 31/10/2022, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 185, 4, p. 1613-1643 31 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Whitehead et al. Response to “Misunderstandings of Multiple Systems Estimation.”

    Whitehead, J., Jackson, J., Balch, A. & Francis, B., 31/10/2022, In: Journal of Human Trafficking. 8, 4, p. 469-473 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Bandit Procedures for Designing Patient-Centric Clinical Trials

    Villar, S. S. & Jacko, P., 21/09/2022, Springer Series in Supply Chain Management. Chen, X., Jasin, S. & Shi, C. (eds.). 1 ed. London: Springer Nature, p. 365-389 25 p. (Springer Series in Supply Chain Management; vol. 18).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  19. Published

    On integrating the number of synthetic data sets m into the a priori synthesis approach

    Jackson, J., Mitra, R., Francis, B. & Dove, I., 14/09/2022, Privacy in Statistical Databases: International Conference, PSD 2022, Paris, France, September 21–23, 2022, Proceedings. Domingo-Ferrer, J. & Laurent, M. (eds.). Cham: Springer, p. 205-219 15 p. (Lecture Notes in Computer Science).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  20. Published

    Estimating quality-adjusted life-years: Assessing the bias induced for a terminal decline quality of life model

    Welsh, A., Costain, D. & Titman, A., 18/07/2022, Proceedings of the 36th International Workshop on Statistical Modelling: July 18-22, 2022 - Trieste, Italy. Torelli, N., Bellio, R. & Muggeo, V. (eds.). EUT Edizioni Università di Trieste, Trieste 2022, p. 354-359 6 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  21. Published

    Using saturated models for data synthesis

    Jackson, J., Francis, B., Mitra, R. & Dove, I., 18/07/2022, Proceedings of the 36th International Workshop on Statistical Modelling: July 18-22, 2022 - Trieste, Italy. Torelli, N., Bellio, R. & Muggeo, V. (eds.). EUT Edizioni Università di Trieste, Trieste 2022, p. 205-210 6 p. 34

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  22. Published

    Baseline and peak cortisol response to the low dose short Synacthen test relates to indication for testing, age and sex

    Park, J., Titman, A., Lancaster, G., Selvarajah, B., Collingwood, C., Powell, D., Das, U., Dharmaraj, P., Didi, M., Senniappan, S. & Blair, J., 30/06/2022, In: Journal of the Endocrine Society. 6, 6, p. bvac043 bvac043.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    An order restricted multi-arm multi-stage clinical trial design

    Serra, A., Mozgunov, P. & Jaki, T., 30/04/2022, In: Statistics in Medicine. 41, 9, p. 1613-1626 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    General tests of the Markov property in multi-state models

    Titman, A. & Putter, H., 30/04/2022, In: Biostatistics. 23, 2, p. 380-396 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    In Honour of Murray Aitkin: Special Issue of <Statistical Modelling>

    Francis, B. (ed.) & Hinde, J. (ed.), 22/04/2022, In: Statistical Modelling. 22, 1-2, p. 1-145 145 p.

    Research output: Contribution to Journal/MagazineSpecial issuepeer-review

  26. Published

    Comparing Data Collection Strategies via Input Uncertainty When Simulating Testing Policies Using Viral Load Profiles

    Parmar, D., Morgan, L., Titman, A., Regnier, E. & Sanchez, S., 28/02/2022, WSC '21: Proceedings of the Winter Simulation Conference. IEEE Press, 12 p. 101

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  27. Published

    Statistical models for Mendelian randomization analysis using summary-level data

    Uche-Ikonne, O., 2022, Lancaster University. 141 p.

    Research output: ThesisDoctoral Thesis

  28. Published

    The use of saturated count models for synthesis of large confidential administrative databases

    Jackson, J., 2022, Lancaster University. 151 p.

    Research output: ThesisDoctoral Thesis

  29. 2021
  30. Published

    Hoehn and Yahr Stage and Striatal Dat-SPECT Uptake Are Predictors of Parkinson’s Disease Motor Progression

    PASADENA Investigators & Prasinezumab Study Group, 13/12/2021, In: Frontiers in Neuroscience. 15, 10 p., 765765.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  31. Published

    Incidence and risk factors of long COVID in the UK: a single-centre observational study

    Nune, A., Durkowski, V., Titman, A., Gupta, L., Hadzhiivanov, M., Ahmed, A., Musat, C. & Sapktoa, H., 9/12/2021, In: The Journal of the Royal College of Physicians of Edinburgh. 51, 4, p. 338-343 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  32. Published

    Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

    Khoo, S. H., Fitzgerald, R., Fletcher, T., Ewings, S., Jaki, T., Lyon, R., Downs, N., Walker, L., Tansley-Hancock, O., Greenhalf, W., Woods, C., Reynolds, H., Marwood, E., Mozgunov, P., Adams, E., Bullock, K., Holman, W., Bula, M. D., Gibney, J. L., Saunders, G., & 18 othersCorkhill, A., Hale, C., Thorne, K., Chiong, J., Condie, S., Pertinez, H., Painter, W., Wrixon, E., Johnson, L., Yeats, S., Mallard, K., Radford, M., Fines, K., Shaw, V., Owen, A., Lalloo, D. G., Jacobs, M. & Griffiths, G., 12/11/2021, In: Journal of Antimicrobial Chemotherapy. 76, 12, p. 3286-3295 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  33. Published

    A permutation test for assessing the presence of individual differences in treatment effects

    Chang, C., Jaki, T., Sadiq, M. S., Kuhlemeier, A., Feaster, D., Cole, N., Lamont, A., Oberski, D., Desai, Y. & Lee Van Horn, M., 1/11/2021, In: Statistical Methods in Medical Research. 30, 11, p. 2369-2381 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  34. E-pub ahead of print

    Proposing a Core Outcome Set for Physical Activity and Exercise Interventions in People With Rare Neurological Conditions

    Ramdharry, G., Buscemi, V., Boaz, A., Dawes, H., Jaki, T., Jones, F., Marsden, J., Paul, L., Playle, R., Randell, E., Robling, M., Rochester, L. & Busse, M., 21/10/2021, (E-pub ahead of print) In: Frontiers in Rehabilitation Sciences. 2, 13 p., 705474.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  35. Published

    Prior elicitation of the efficacy and tolerability of Methotrexate and Mycophenolate Mofetil in Juvenile Localised Scleroderma

    Desai, Y., Jaki, T., Beresford, M. W., Burnett, T., Eleftheriou, D., Jacobe, H., Leone, V., Li, S., Mozgunov, P., Ramanan, A. V., Torok, K. S., Anderson, M. E., Anton, J., Avcin, T., Felton, J., Foeldvari, I., Laguda, B., McErlane, F., Shaw, L., Zulian, F., & 1 othersPain, C. E., 9/09/2021, In: AMRC Open Research. 3, p. 20 1 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  36. Published

    Optimizing subgroup selection in two-stage adaptive enrichment and umbrella designs

    Ballarini, N. M., Burnett, T., Jaki, T., Jennison, C., König, F. & Posch, M., 31/05/2021, In: Statistics in Medicine. 40, 12, p. 2939-2956 18 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  37. Published

    Applying methods for personalized medicine to the treatment of alcohol use disorder

    Kuhlemeier, A., Desai, Y., Tonigan, A., Witkiewitz, K., Jaki, T., Hsiao, Y-Y., Chang, C. & Van Horn, M. L., 30/04/2021, In: Journal of Consulting and Clinical Psychology. 89, 4, p. 288-300 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  38. Published

    Bridging across patient subgroups in phase I oncology trials that incorporate animal data

    Zheng, H., Hampson, L. V. & Jaki, T., 1/04/2021, In: Statistical Methods in Medical Research. 30, 4, p. 1057-1071 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  39. Published

    To Adjust or Not to Adjust? When a "Confounder" Is Only Measured After Exposure

    Groenwold, R. H. H., Palmer, T. M. & Tilling, K., 31/03/2021, In: Epidemiology. 32, 2, p. 194-201 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  40. Published

    Recurrent events modelling of haemophilia bleeding events

    Titman, A., Wolfsegger, M. J. & Jaki, T., 1/03/2021, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 70, 2, p. 351-371 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  41. Published

    Software Application Profile: Bayesian estimation of inverse variance weighted and MR-Egger models for two-sample Mendelian randomization studies-mrbayes

    Uche-Ikonne, O., Dondelinger, F. & Palmer, T., 28/02/2021, In: International Journal of Epidemiology. 50, 1, p. 43-49 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  42. Published

    Adaptive enrichment trials: What are the benefits?

    Burnett, T. & Jennison, C., 10/02/2021, In: Statistics in Medicine. 40, 3, p. 690-711 22 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  43. 2020
  44. Published

    Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs

    Burnett, T., Mozgunov, P., Pallmann, P., Villar, S. S., Wheeler, G. M. & Jaki, T., 19/11/2020, In: BMC Medicine. 18, 1, 21 p., 352.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  45. Published

    An information-theoretic approach for selecting arms in clinical trials

    Mozgunov, P. & Jaki, T. F., 10/11/2020, In: Journal of the Royal Statistical Society: Series B (Statistical Methodology). 82, 5, p. 1223-1247 25 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  46. Published

    Salivary cortisol, cortisone and serum cortisol concentrations are related to age and body mass index in healthy children and young people

    Titman, A., Price, V., Hawcutt, D., Chesters, C., Ali, M., Cacace, G., Lancaster, G., Peak, M. & Blair, J. C., 31/10/2020, In: Clinical Endocrinology. 93, 5, p. 572-578 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  47. Published

    Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

    Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T. S., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B. E., Chen, Y., Matic, L., & 63 othersGale, J. D., Lee, J., Zhang, W., Quazi, A., Ala-Korpela, M., Choi, S. H., Claringbould, A., Danesh, J., Davey Smith, G., de Masi, F., Elmståhl, S., Engström, G., Fauman, E., Fernandez, C., Franke, L., Franks, P. W., Giedraitis, V., Haley, C., Hamsten, A., Ingason, A., Johansson, Å., Joshi, P. K., Lind, L., Lindgren, C. M., Lubitz, S., Palmer, T., Macdonald-Dunlop, E., Magnusson, M., Melander, O., Michaelsson, K., Morris, A. P., Mägi, R., Nagle, M. W., Nilsson, P. M., Nilsson, J., Orho-Melander, M., Polasek, O., Prins, B., Pålsson, E., Qi, T., Sjögren, M., Sundström, J., Surendran, P., Võsa, U., Werge, T., Wernersson, R., Westra, H-J., Yang, J., Zhernakova, A., Ärnlöv, J., Fu, J., Smith, J. G., Esko, T., Hayward, C., Gyllensten, U., Landen, M., Siegbahn, A., Wilson, J. F., Wallentin, L., Butterworth, A. S., Holmes, M. V., Ingelsson, E. & Mälarstig, A., 16/10/2020, In: Nature Metabolism. 2, 10, p. 1135-1148 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  48. Published

    Statistics and the “little grey cells”

    Jackson, J., 1/10/2020, In: Significance. 17, 5, p. 10-11 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  49. Published

    A Critical Review of Graphics for Subgroup Analyses in Clinical Trials

    Ballarini, N. M., Chiu, Y-D., Koenig, F., Posch, M. & Jaki, T., 1/09/2020, In: Pharmaceutical Statistics. 19, 5, p. 541-560 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  50. Published

    Bias induced during the estimation of quality-adjusted life-years

    Welsh, A., 08/2020. 5 p.

    Research output: Contribution to conference - Without ISBN/ISSN Conference paper

  51. Published

    Covid-19 deaths: How are gender, age and underlying health condition related?

    Jackson, J., 27/07/2020, In: Significance. 680.

    Research output: Contribution to Journal/MagazineJournal article

  52. Published

    Bias induced during the estimation of quality-adjusted life-years

    Welsh, A., Costain, D. & Titman, A., 20/07/2020, Proceedings of the 35th International Workshop on Statistical Modelling. 5 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  53. Published

    Attitudes to immigration and human values – a repeated cross-sectional study in three European countries

    Hoti, V., 14/07/2020, Lancaster University. 237 p.

    Research output: ThesisDoctoral Thesis

  54. Published

    Discussion on the paper by Silverman (2020): James Jackson (Lancaster University)

    Jackson, J., 1/06/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 3

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  55. Published

    Estimation of treatment effects following a sequential trial of multiple treatments

    Whitehead, J., Desai, Y. & Jaki, T., 20/05/2020, In: Statistics in Medicine. 39, 11, p. 1593-1609 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  56. Published

    A benchmark for dose finding studies with continuous outcomes

    Mozgunov, P., Jaki, T. F. & Paoletti, X., 1/04/2020, In: Biostatistics. 21, 2, p. 189–201 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  57. Published

    A quantitative framework to inform extrapolation decisions in children

    Wadsworth, I., Hampson, L. V., Jaki, T., Sills, G. J., Marson, A. G. & Appleton, R., 1/02/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 2, p. 515-534 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  58. E-pub ahead of print

    Dynamic inference for non-Markov transition probabilities under random right-censoring

    Dobler, D. & Titman, A. C., 14/01/2020, (E-pub ahead of print) In: Scandinavian Journal of Statistics. 47, 2, p. 572-586 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  59. Published

    Confidentiality challenges in releasing longitudinally linked data

    Mitra, R., Blanchard, S., Dove, I., Tudor, C. & Spicer, K., 2020, In: Transactions on Data Privacy. 13, 2, p. 151-170 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  60. Published
  61. 2019
  62. Published

    A Review of the National Male Survivors Helpline and Online Service - Project Report

    Weare, S., Hulley, J. & Pattinson, B., 11/11/2019, Lancaster: Lancaster University. 40 p.

    Research output: Book/Report/ProceedingsCommissioned report

  63. Published

    A flexible design for advanced Phase I/II clinical trials with continuous efficacy endpoints

    Mozgunov, P. & Jaki, T., 1/11/2019, In: Biometrical Journal. 61, 6, p. 1477-1492 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  64. Published

    Subgroup analysis of treatment effects for misclassified biomarkers with time-to-event data

    Wan, F., Titman, A. & Jaki, T., 1/11/2019, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 68, 5, p. 1447-1463 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  65. Published

    Loss Functions in Restricted Parameter Spaces and Their Bayesian Applications

    Mozgunov, P., Jaki, T. F. & Gasparini, M., 3/10/2019, In: Journal of Applied Statistics. 46, 13, p. 2314-2337 24 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  66. E-pub ahead of print

    Bayesian estimation of IVW and MR-Egger models for two-sample Mendelian randomization studies

    Uche-Ikonne, O., Dondelinger, F. & Palmer, T., 21/09/2019, (E-pub ahead of print) https://doi.org/10.1101/19005868: medRxiv.

    Research output: Working paper

  67. Published

    A novel measure of drug benefit–risk assessment based on Scale Loss Score

    Saint-Hilary, G., Robert, V., Gasparini, M., Jaki, T. F. & Mozgunov, P., 1/09/2019, In: Statistical Methods in Medical Research. 28, 9, p. 2738-2753 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  68. Published

    ‘Cost’ calculations as a barrier to gaining information under the Freedom of Information Act 2000 from the Police in England and Wales

    Kingston, S. E., Elliott, A. & Thomas, T., 1/08/2019, In: Policing and Society: An International Journal of Research and Policy. 29, 7, p. 834-847 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  69. Published

    A Bayesian model to estimate the cutoff and the clinical utility of a biomarker assay

    Vradi, E., Jaki, T. F., Vonk, R. & Brannath, W., 1/08/2019, In: Statistical Methods in Medical Research. 28, 8, p. 2538-2556 19 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  70. Published

    The effects of sample size on the estimation of regression mixture models

    Jaki, T. F., Kim, M., Lamont, A. E., George, M., Feaster, D. & Van Horn, M. L., 1/04/2019, In: Educational and Psychological Measurement. 79, 2, p. 358-384 27 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  71. Published

    Instrumental variable estimation in semi-parametric additive hazards models

    Brueckner, M., Titman, A. C. & Jaki, T. F., 1/03/2019, In: Biometrics. 75, 1, p. 110-120 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  72. Published

    The influence of temperature on nutrient supply and demand: host plant quality is temperature dependent

    Clissold, F. J., Woodman, J. D., Wilson, K. & Simpson, S. J., 1/03/2019, In: INTEGRATIVE AND COMPARATIVE BIOLOGY. 59, Suppl. 1, p. E39-E39 1 p.

    Research output: Contribution to Journal/MagazineMeeting abstractpeer-review

  73. Published

    The interactive impact of temperature and nutrition on disease resistance

    Clissold, F. J., Woodman, J. D., Wilson, K. & Simpson, S. J., 1/03/2019, In: INTEGRATIVE AND COMPARATIVE BIOLOGY. 59, Suppl. 1, p. E39-E39 1 p.

    Research output: Contribution to Journal/MagazineMeeting abstractpeer-review

  74. Published

    Quantifying the association between progression-free survival and overall survival in oncology trials using Kendall's tau.

    Weber, E. & Titman, A. C., 28/02/2019, In: Statistics in Medicine. 38, 5, p. 703-719 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  75. Published

    The R package MAMS for designing multi-arm multi-stage clinical trials

    Jaki, T. F., Pallmann, P. S. & Magirr, D., 31/01/2019, In: Journal of Statistical Software. 88, 4, 25 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  76. E-pub ahead of print

    A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials

    Zheng, H., Hampson, L. V. & Wandel, S., 16/01/2019, (E-pub ahead of print) In: Statistical Methods in Medical Research. 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  77. Published

    Bayesian adaptive methods to incorporate preclinical data into phase I clinical trials

    Zheng, H., 2019, Lancaster University. 176 p.

    Research output: ThesisDoctoral Thesis

  78. Published

    Investigating the association between socio-economic position and stillbirth in Brazil and the UK

    Jones, A., 2019, Lancaster University. 318 p.

    Research output: ThesisDoctoral Thesis

  79. 2018
  80. Published

    An alternative method to analyse the Biomarker-strategy design

    Kunz, C. U., Jaki, T. F. & Stallard, N., 30/12/2018, In: Statistics in Medicine. 37, 30, p. 4636-4651 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  81. Published

    Design and estimation in clinical trials with subpopulation selection

    Chiu, Y-D., Koenig, F., Posch, M. & Jaki, T. F., 20/12/2018, In: Statistics in Medicine. 37, 29, p. 4335-4352 18 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  82. Published

    Data collection on trafficking in human beings in the EU: Final report

    Francis, B., Walby, S., Pattinson, B., Elliott, A., Hoti - Llabjani, V., Phoenix, J., Verrall, R. & Peelo, M., 4/12/2018, Luxembourg: European Commission. 272 p.

    Research output: Book/Report/ProceedingsCommissioned report

  83. E-pub ahead of print

    The role of the home environment in neurocognitive development of children living in extreme poverty and with frequent illnesses: a cross-sectional study

    Nampijja, M., Kizindo, R., Apule, B., Lule, S. A., Muhangi, L., Titman, A., Elliott, A., Alcock, K. J. & Lewis, C. N., 3/12/2018, (E-pub ahead of print) In: Wellcome Open Research. 3, 17 p., 152.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  84. E-pub ahead of print

    Randomized dose-escalation designs for drug combination cancer trials with immunotherapy

    Mozgunov, P., Jaki, T. F. & Paoletti, X., 23/10/2018, (E-pub ahead of print) In: Journal of Biopharmaceutical Statistics. 29, 2, p. 359-377 19 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  85. Published

    Creation of the WHO Indicators of Infant and Young Child Development (IYCD): metadata synthesis across 10 countries

    Lancaster, G. A., McCray, G., Kariger, P., Dua, T., Titman, A., Chandna, J., McCoy, D., Abubakar, A., Hamadani, J. D., Fink, G., Tofail, F., Gladstone, M. & Janus, M., 16/10/2018, In: BMJ Global Health. 3, 5, 15 p., e000747.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  86. Published

    Optimal design when outcome values are not missing at random

    Lee, K., Mitra, R. & Biedermann, S., 1/10/2018, In: Statistica Sinica. 28, 4, p. 1821-1838 18 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  87. E-pub ahead of print

    Software Application Profile: mrrobust - A Tool For Performing Two-Sample Summary Mendelian Randomization Analyses

    Spiller, W., Davies, N. & Palmer, T. M., 12/09/2018, (E-pub ahead of print) In: International Journal of Epidemiology.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  88. Published

    Performance of different clinical trial designs to evaluate treatments during an epidemic

    Brueckner, M., Titman, A. C., Jaki, T. F., Rojek, A. & Horby, P. W., 11/09/2018, In: PLoS ONE. 13, 9, 19 p., e0203387.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  89. Published

    Bayesian spatial monotonic multiple regression

    Rohrbeck, C., Costain, D. A. & Frigessi, A., 1/09/2018, In: Biometrika. 105, 3, p. 691-707 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  90. Published

    A proposal for a new PhD level curriculum on quantitative methods for drug development

    Jaki, T. F., Gordon, A., Forster, P. S., Bijnens, L., Bornkamp, B., Brannath, W., Fontana, R., Gasparini, M., Hampson, L. V., Jacobs, T., Jones, B., Paoletti, X., Posch, M., Titman, A. C., Vonk, R. & Koenig, F., 09/2018, In: Pharmaceutical Statistics. 17, 5, p. 593-606 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  91. Published

    Dose-escalation strategies which utilise subgroup information

    Cotterill, A. & Jaki, T. F., 09/2018, In: Pharmaceutical Statistics. 17, 5, p. 414-436 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  92. Published

    Model selection based on combined penalties for biomarker identification

    Vradi, E., Brannath, W., Jaki, T. & Vonk, R., 4/07/2018, In: Journal of Biopharmaceutical Statistics. 28, 4, p. 735-749 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  93. E-pub ahead of print

    An information-theoretic Phase I/II design for molecularly targeted agents that does not require an assumption of monotonicity

    Mozgunov, P. & Jaki, T. F., 15/06/2018, (E-pub ahead of print) In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 68, 2, p. 347-367 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  94. Published

    Attachment and therapeutic alliance in psychological therapy for people with recent onset psychosis who use cannabis

    Berry, K., Palmer, T. M., Gregg, L., Barrowclough, C. & Lobban, A. F., 6/06/2018, In: Clinical Psychology and Psychotherapy. 25, 3, p. 440-445 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  95. Published

    Statistical challenges of administrative and transaction data: Contribution to discussion

    Babb, P., Zhang, L-C., Allin, P., Wallgren, A., Wallgren, B., Blunt, G., Garrett, A., Murtagh, F., Smith, P. W. F., Elliott, D., Nason, G., Powell, B., Moore, J. C., Durrant, G. B., Smith, P. W. F., Smith, P. A., Chambers, R. L., Herzberg, A. M., Pilling, M., Appleby, W., & 36 othersBarnett, A., Bhansali, R., Bharadwaj, N., Dong, Y., van den Brakel, J. A., Budd, L., Doidge, J., Gilbert, R., Francis, B., Frisoli, K., Nugent, R., Garcia Perez, F. J., Lara, L., Porcu, E., Henry, S., Hunt, I., Ieva, F., Gasperoni, F., Jansson, I., Kumar, K., Longford, N., Manninen, A., Mateu, J., McNicholas, P. D., McNicholas, S. M., Tait, P. A., Mehew, J., Oberski, D. L., Ruiz, M., Yohai, V. J., Zamar, R., Stehlik, M., Stehlikova, S., Nunez Soza, L., Towers, J. & Wijayatunga, P., 06/2018, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 181, 3, p. 578-605 28 p.

    Research output: Contribution to Journal/MagazineEditorialpeer-review

  96. Published

    UK Families with Children with Rare Chromosome Disorders: Changing Experiences of Diagnosis and Counseling (2003 to 2013)

    Szczepura, A., Wynn, S., Searle, B., Khan, A., Palmer, T. M., Biggerstaff, D., Elliott, J. & Hulten, M., 05/2018, In: Clinical Genetics. 93, 5, p. 972-981 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  97. Published

    A review of the deterministic and diffusion approximations for stochastic chemical reaction networks

    Mozgunov, P., Beccuti, M., Horvath, A., Jaki, T. F., Sirovich, R. & Bibbona, E., 04/2018, In: Reaction Kinetics, Mechanisms and Catalysis. 123, 2, p. 289-312 24 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  98. Published

    Instrumental variable methods for a binary outcome were used to informatively address non-compliance in a randomised trial in surgery

    Cook, J. A., Maclennan, G. S., Palmer, T., Lois, N. & Emsley, R., 04/2018, In: Journal of Clinical Epidemiology. 96, p. 126-132 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  99. Published

    Reading comprehension difficulties in children with rolandic epilepsy

    Currie, N. K., Lew, A. R., Palmer, T. M., Basu, H., De Goede, C., Ayer, A. & Cain, K., 03/2018, In: Developmental Medicine and Child Neurology. 60, 3, p. 275-282 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  100. Published
  101. Published

    Extrapolation of efficacy and other data to support the development of new medicines for children: a systematic review of methods

    Wadsworth, I., Hampson, L. V. & Jaki, T. F., 1/02/2018, In: Statistical Methods in Medical Research. 27, 2, p. 398-413 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  102. Published

    PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer

    Ghaneh, P., Hanson, R., Titman, A., Lancaster, G. A., Plumpton, C., Lloyd-Williams, H., Yeo, S. T., Edwards, R. T., Johnson, C., Abu Hilal, M., Higginson, A. P., Armstrong, T., Smith, A., Scarsbrook, A., McKay, C., Carter, R., Sutcliffe, R. P., Bramhall, S., Kocher, H. M., Cunningham, D., & 20 othersPereira, S. P., Davidson, B., Chang, D., Khan, S., Zealley, I., Sarker, D., Al Sarireh, B., Charnley, R., Lobo, D., Nicolson, M., Halloran, C., Raraty, M., Sutton, R., Vinjamuri, S., Evans, J., Campbell, F., Deeks, J., Sanghera, B., Wong, W-L. & Neoptolemos, J. P., 02/2018, In: Health Technology Assessment. 22, 7, p. 1-114 114 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  103. Published

    A review of statistical updating methods for clinical prediction models

    Su, T-L., Jaki, T. F., Hickey, G., Buchan, I. & Sperrin, M., 1/01/2018, In: Statistical Methods in Medical Research. 27, 1, p. 185-197 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  104. Published

    Identification of Predicted Individual Treatment Effects (PITE) in randomized clinical trials

    Lamont, A. E., Lyons, M., Jaki, T. F., Stuart, E. A., Feaster, D., Ishwaran, H., Tharmaratnam, K. & Van Horn, M. L., 1/01/2018, In: Statistical Methods in Medical Research. 27, 1, p. 142-157 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  105. Published
  106. Unpublished

    Developing robust statistical scoring methods for use in child assessment tools

    Gichuru, P. K., 2018, (Unpublished) Lancaster University. 290 p.

    Research output: ThesisDoctoral Thesis

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