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Medical and Social Statistics

  1. Published

    Incorporating data received after a sequential trial has stopped into the final analysis: implementation and comparison of methods.

    Whitehead, J., Bollard, K., Matsushita, T., Sooriyarachchi, M. R. & Whitehead, A., 09/2003, In: Biometrics. 59, 3, p. 701-709 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    Sequential genome-wide association studies for monitoring adverse events in clinical evaluation of new drugs.

    Whitehead, J., Kelly, P. J., Stallard, N., Zhou, Y. & Bowman, C., 30/09/2006, In: Statistics in Medicine. 25, 18, p. 3081-3092 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Implementation of a Bayesian design in a dose-escalation study of an experimental agent in healthy volunteers.

    Whitehead, J., Korhonen, P., Mustonen, M. & Zhou, Y., 03/2008, In: Biometrics. 64, 1, p. 299-308 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Meta-Analysis of Controlled Clinical Trials.

    Whitehead, A., 2002, John Wiley. 352 p.

    Research output: Book/Report/ProceedingsBook

  5. Published

    Meta-analysis of ordinal outcomes using individual patient data.

    Whitehead, A., Higgins, J. P. T., Omar, R. Z. & Savaluny, E., 15/08/2001, In: Statistics in Medicine. 20, 15, p. 2243-2260 18 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint.

    Whitehead, J. & Jaki, T., 28/02/2009, In: Statistics in Medicine. 28, 5, p. 828-847 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    A simple two-stage design for quantitative responses with appliction to a study in diabectic neuropathic pain.

    Whitehead, J., Valdés-Márquez, E. & Lissmats, A., 04/2009, In: Pharmaceutical Statistics. 8, 2, p. 125-135 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Using historical lesion volume data in the design of a new phase II clinical trial in acute stroke.

    Whitehead, J., Bolland, K., Valdés-Márquez, E., Lihic, A., Ali, M. & Lees, K., 04/2009, In: Stroke. 40, 4, p. 1347-1352 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    A combined score test for binary and ordinal endpoints from clinical trials.

    Whitehead, J., Branson, M. & Todd, S., 28/02/2010, In: Statistics in Medicine. 29, 5, p. 521-532 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme.

    Whitehead, J., Kelly, P., Zhou, Y., Stallard, N., Thygesen, H. & Bowman, C., 10/2009, In: Pharmaceutical Statistics. 8, 4, p. 287-300 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Fitting models for the joint action of two drugs using SAS(R).

    Whitehead, A., Whitehead, J., Todd, S., Zhou, Y. & Smith, M. K., 10/2008, In: Pharmaceutical Statistics. 7, 4, p. 272-284 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Incorporating intermediate binary responses into interim analyses of clinical trials : a comparison of four methods.

    Whitehead, A., Sooriyarachchi, M. R., Whitehead, J. & Bolland, K., 10/05/2008, In: Statistics in Medicine. 27, 10, p. 1646-1666 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    A Bayesian approach for dose-escalation in a phase I clinical trial incorporating pharmacodynamic endpoints .

    Whitehead, J., Hampson, L., Zhou, Y., Ledent, E. & Pereira, A., 11/2007, In: Journal of Biopharmaceutical Statistics. 17, 6, p. 1117-1129 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Bayesian procedures for phase I/II clinical trials investigating the safety and efficacy of drug combinations

    Whitehead, J., Thygesen, H. & Whitehead, A., 20/07/2011, In: Statistics in Medicine. 30, 16, p. 1952-1970 19 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    A Bayesian dose-escalation procedure for phase I clinical trials based only on the assumption of monotonicity.

    Whitehead, J., Thygesen, H. & Whitehead, A., 30/07/2010, In: Statistics in Medicine. 29, 17, p. 1808-1824 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Bayesian sample size for exploratory clinical trials incorporating historical data.

    Whitehead, J., Valdés-Márquez, E., Johnson, P. & Graham, G., 06/2008, In: Statistics in Medicine. 27, 13, p. 2307-2327 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    A novel phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer

    Whitehead, J., Thygesen, H., Jaki, T., Davis, S., Halford, S., Turner, H., Cook, N. & Jodrell, D., 15/08/2012, In: Statistics in Medicine. 31, 18, p. 1931-1943 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Bayesian sample sizes for exploratory clinical trials comparing multiple experimental treatments with a control

    Whitehead, J., Cleary, F. & Turner, A., 30/05/2015, In: Statistics in Medicine. 34, 12, p. 2048-2061 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Cholesterol-lowering effects of oat beta-glucan: a meta-analysis of randomized controlled trials

    Whitehead, A., Beck, E. J., Tosh, S. & Wolever, T. M. S., 1/12/2014, In: American Journal of Clinical Nutrition. 100, 6, p. 1413-1421 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    A comparison of the barely Bayesian design with the triangular test for clinical trials in infectious diseases

    Whitehead, J. R., 08/2016, In: Clinical Trials. 13, 4, p. 451-453 3 p.

    Research output: Contribution to Journal/MagazineLetterpeer-review

  21. Published

    Trial design for evaluating novel treatments during an outbreak of an infectious disease

    Whitehead, J. R., Olliaro, P., Lang, T. & Horby, P. W., 02/2016, In: Clinical Trials. 13, 1, p. 31-38 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Estimation of treatment effects following a sequential trial of multiple treatments

    Whitehead, J., Desai, Y. & Jaki, T., 20/05/2020, In: Statistics in Medicine. 39, 11, p. 1593-1609 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Whitehead et al. Response to “Misunderstandings of Multiple Systems Estimation.”

    Whitehead, J., Jackson, J., Balch, A. & Francis, B., 31/10/2022, In: Journal of Human Trafficking. 8, 4, p. 469-473 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Gassing during the growth of bacteriological infection.

    Whittaker, J. C., Francis, B. J. & Whittaker, J., 1996, In: Student. 1, 3, p. 211-214 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Physical restraint of patients in acute mental health care settings : patient, staff, and enviromental factors associated with the use of a horizontal restraint position.

    Whittington, R., Lancaster, G. A., Meehan, C., Lane, S. & Riley, D., 06/2006, In: Journal of Forensic Psychiatry and Psychology. 17, 2, p. 253-265 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  26. Published

    Longitudinal trends in using physical interventions to manage aggression and self-harm in mental health services

    Whittington, R., Leitner, M., Barr, W., Lancaster, G. & McGuire, J., 2012, In: Psychiatric Services. 63, 5, p. 488-492 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  27. Published

    TRAMSS website: teaching resources and materials for social scientists

    Wiggins, D., Beedham, H., Francis, B., Goldstein, H., Hanavy, M., Harman, J., Leyland, A., Rasbash, J. & Smith, F., 1999

    Research output: Exhibits, objects and web-based outputsWeb publication/site

  28. Published

    Manual vs. integrated automatic load-distributing band CPR with equal survival after out of hospital cardiac arrest: the randomized CIRC trial

    Wik, L., Olsen, J-A., Persse, D., Sterz, F., Lozano Jr, M., Brouwer, M. A., Westfall, M., Souders, C., Malzer, R., Grunsven, P. M. V., Travis, D., Whitehead, A., Herken, U. R. & Lerner, E. B., 06/2014, In: Resuscitation. 85, 6, p. 741-748 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  29. Published

    Meta-analysis of method comparison studies.

    Williamson, P. R., Lancaster, G. A., Craig, J. V. & Smyth, R. L., 30/07/2002, In: Statistics in Medicine. 21, 14, p. 2013-2025 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  30. Published

    Statistical education for PhD students in UK medical schools

    Williamson, P. & Lancaster, G., 2004, In: Statistics Education Research Journal. 3, 1, p. 72-79 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  31. Published

    A Bayesian adaptive design for clinical trials in rare diseases

    Williamson, F., Jacko, P., Villar, S. S. & Jaki, T. F., 09/2017, In: Computational Statistics and Data Analysis. 113, p. 136-153 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  32. Published

    Effects of over-winter fumigation with sulfur and nitrogen dioxides on biochemical parameters and spring growth in red spruce

    Wolfenden, J., Pearson, M. & Francis, B., 01/1991, In: Plant, Cell and Environment. 14, 1, p. 35-45 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  33. Published

    Progress towards the early diagnosis of forest decline.

    Wolfenden, J., Cape, J. N., Francis, B., Melhorn, H. & Wellburn, A., 1991, Acid Depositions in Europe: Environmental Effects, Strategies and Policy Options. Chadwick, M. J. & Hutton, M. (eds.). Stockholm: Stockholm Environment Institute, p. 59-79 21 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter (peer-reviewed)

  34. Published

    Use of carotenoid ratios, ethylene emissions and buffer capacities for the early diagnosis of forest decline.

    Wolfenden, J., Robinson, D. C., Cape, J. N., Paterson, I. S., Francis, B., Mehlhorn, H. & Wellburn, A., 05/1988, In: New Phytologist. 109, 1, p. 85-95 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  35. Published

    A note on statistical analysis of organ weights in non-clinical toxicological studies.

    Wolfsegger, M. J., Jaki, T., Dietrich, B., Kunzler, J. A. & Barker, K., 10/2009, In: Toxicology and Applied Pharmacology. 240, 1, p. 117-122 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  36. Published

    Non-compartmental estimation of pharmacokinetic parameters in serial sampling designs.

    Wolfsegger, M. J. & Jaki, T., 10/2009, In: Journal of Pharmacokinetics and Pharmacodynamics. 36, 5, p. 479-494

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  37. Published

    Assessing systemic drug exposure in repeated dose toxicity studies in the case of complete and incomplete sampling.

    Wolfsegger, M. J. & Jaki, T., 12/2009, In: Biometrical Journal. 51, 6, p. 1017-1026 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  38. Published

    Estimation of AUC from 0 to Infinity in Serial Sacrifice Designs.

    Wolfsegger, M. J. & Jaki, T., 12/2005, In: Journal of Pharmacokinetics and Pharmacodynamics. 32, 5-6, p. 757-766 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  39. Published

    Simultaneous confidence intervals by iteratively adjusted alpha for relative effects in the one-way layout.

    Wolfsegger, M. J. & Jaki, T., 2006, In: Statistics and Computing. 16, 1, p. 15-23 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  40. Published

    A hybrid method to estimate the minimum effective dose for monotone and non-monotone dose-response relationships

    Wolfsegger, M. J., Gutjahr, G., Engl, W. & Jaki, T., 2014, In: Biometrics. 70, 1, p. 103-109 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  41. Published

    Molecular analysis to detect pancreatic ductal adenocarcinoma in high-risk groups

    Yan, L., McFaul, C., Howes, N., Leslie, J., Lancaster, G., Wong, T., Threadgold, J., Evans, J., Gilmore, I., Smart, H., Lombard, M., Neoptolemos, J. & Greenhalf, W., 06/2005, In: Gastroenterology. 128, 7, p. 2124-2130 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  42. E-pub ahead of print

    A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials

    Zheng, H., Hampson, L. V. & Wandel, S., 16/01/2019, (E-pub ahead of print) In: Statistical Methods in Medical Research. 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  43. Published

    Bayesian adaptive methods to incorporate preclinical data into phase I clinical trials

    Zheng, H., 2019, Lancaster University. 176 p.

    Research output: ThesisDoctoral Thesis

  44. Published

    Bridging across patient subgroups in phase I oncology trials that incorporate animal data

    Zheng, H., Hampson, L. V. & Jaki, T., 1/04/2021, In: Statistical Methods in Medical Research. 30, 4, p. 1057-1071 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  45. Published

    Computation of an exact confidence set for a maximum point of a univariate polynomial function in a given interval

    Zhou, S., Wan, F., Liu, W. & Bretz, F., 03/2017, In: Statistics and Probability Letters. 122, p. 157-161 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  46. Published

    Confidence Intervals for the Treatment Effects in Adaptive Enrichment Designs

    Zhu, J., 2023, Lancaster University. 118 p.

    Research output: ThesisDoctoral Thesis

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