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Medical and Social Statistics

  1. 2021
  2. Forthcoming

    Comparing Data Collection Strategies via Input Uncertainty When Simulating Testing Policies Using Viral Load Profiles

    Parmar, D., Morgan, L., Titman, A., Sanchez, S. & Regnier, E., 18/06/2021, (Accepted/In press).

    Research output: Contribution to conference - Without ISBN/ISSN Conference paperpeer-review

  3. Published

    Optimizing subgroup selection in two-stage adaptive enrichment and umbrella designs

    Ballarini, N. M., Burnett, T., Jaki, T., Jennison, C., König, F. & Posch, M., 31/05/2021, In: Statistics in Medicine. 40, 12, p. 2939-2956 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Bridging across patient subgroups in phase I oncology trials that incorporate animal data

    Zheng, H., Hampson, L. V. & Jaki, T., 1/04/2021, In: Statistical Methods in Medical Research. 30, 4, p. 1057-1071 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Recurrent events modelling of haemophilia bleeding events

    Titman, A., Wolfsegger, M. J. & Jaki, T., 31/03/2021, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 70, 2, p. 351-371 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    To Adjust or Not to Adjust? When a "Confounder" Is Only Measured After Exposure

    Groenwold, R. H. H., Palmer, T. M. & Tilling, K., 31/03/2021, In: Epidemiology. 32, 2, p. 194-201 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Adaptive enrichment trials: What are the benefits?

    Burnett, T. & Jennison, C., 10/02/2021, In: Statistics in Medicine. 40, 3, p. 690-711 22 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. 2020
  9. Published

    Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs

    Burnett, T., Mozgunov, P., Pallmann, P., Villar, S. S., Wheeler, G. M. & Jaki, T., 19/11/2020, In: BMC Medicine. 18, 1, 21 p., 352.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    An information-theoretic approach for selecting arms in clinical trials

    Mozgunov, P. & Jaki, T. F., 10/11/2020, In: Journal of the Royal Statistical Society: Series B (Statistical Methodology). 82, 5, p. 1223-1247 25 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. E-pub ahead of print

    Whitehead et al. Response to “Misunderstandings of Multiple Systems Estimation.”

    Whitehead, J., Jackson, J., Balch, A. & Francis, B., 6/11/2020, In: Journal of Human Trafficking. 5 p.

    Research output: Contribution to journalComment/debatepeer-review

  12. Published

    Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

    Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T. S., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B. E., Chen, Y., Matic, L. & 63 others, Gale, J. D., Lee, J., Zhang, W., Quazi, A., Ala-Korpela, M., Choi, S. H., Claringbould, A., Danesh, J., Davey Smith, G., de Masi, F., Elmståhl, S., Engström, G., Fauman, E., Fernandez, C., Franke, L., Franks, P. W., Giedraitis, V., Haley, C., Hamsten, A., Ingason, A., Johansson, Å., Joshi, P. K., Lind, L., Lindgren, C. M., Lubitz, S., Palmer, T., Macdonald-Dunlop, E., Magnusson, M., Melander, O., Michaelsson, K., Morris, A. P., Mägi, R., Nagle, M. W., Nilsson, P. M., Nilsson, J., Orho-Melander, M., Polasek, O., Prins, B., Pålsson, E., Qi, T., Sjögren, M., Sundström, J., Surendran, P., Võsa, U., Werge, T., Wernersson, R., Westra, H-J., Yang, J., Zhernakova, A., Ärnlöv, J., Fu, J., Smith, J. G., Esko, T., Hayward, C., Gyllensten, U., Landen, M., Siegbahn, A., Wilson, J. F., Wallentin, L., Butterworth, A. S., Holmes, M. V., Ingelsson, E. & Mälarstig, A., 16/10/2020, In: Nature Metabolism. 2, 10, p. 1135-1148 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Statistics and the “little grey cells”

    Jackson, J., 1/10/2020, In: Significance. 17, 5, p. 10-11 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    A Critical Review of Graphics for Subgroup Analyses in Clinical Trials

    Ballarini, N. M., Chiu, Y-D., Koenig, F., Posch, M. & Jaki, T., 1/09/2020, In: Pharmaceutical Statistics. 19, 5, p. 541-560 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Bias induced during the estimation of quality-adjusted life-years

    Welsh, A., Costain, D. & Titman, A., 08/2020. 5 p.

    Research output: Contribution to conference - Without ISBN/ISSN Conference paper

  16. Published

    Covid-19 deaths: How are gender, age and underlying health condition related?

    Jackson, J., 27/07/2020, In: Significance. 680.

    Research output: Contribution to journalJournal article

  17. Published

    Attitudes to immigration and human values – a repeated cross-sectional study in three European countries

    Hoti, V., 14/07/2020, Lancaster University. 237 p.

    Research output: ThesisDoctoral Thesis

  18. Published

    Discussion on the paper by Silverman (2020): James Jackson (Lancaster University)

    Jackson, J., 1/06/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 3

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Estimation of treatment effects following a sequential trial of multiple treatments

    Whitehead, J., Desai, Y. & Jaki, T., 20/05/2020, In: Statistics in Medicine. 39, 11, p. 1593-1609 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    A benchmark for dose finding studies with continuous outcomes

    Mozgunov, P., Jaki, T. F. & Paoletti, X., 1/04/2020, In: Biostatistics. 21, 2, p. 189–201 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    A quantitative framework to inform extrapolation decisions in children

    Wadsworth, I., Hampson, L. V., Jaki, T., Sills, G. J., Marson, A. G. & Appleton, R., 1/02/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 2, p. 515-534 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. E-pub ahead of print

    Dynamic inference for non-Markov transition probabilities under random right-censoring

    Dobler, D. & Titman, A. C., 14/01/2020, In: Scandinavian Journal of Statistics. 47, 2, p. 572-586 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Confidentiality challenges in releasing longitudinally linked data

    Mitra, R., Blanchard, S., Dove, I., Tudor, C. & Spicer, K., 2020, In: Transactions on Data Privacy. 13, 2, p. 151-170 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published
  25. 2019
  26. Published

    A Review of the National Male Survivors Helpline and Online Service - Project Report

    Weare, S., Hulley, J. & Pattinson, B., 11/11/2019, Lancaster: Lancaster University. 40 p.

    Research output: Book/Report/ProceedingsCommissioned report

  27. Published

    A flexible design for advanced Phase I/II clinical trials with continuous efficacy endpoints

    Mozgunov, P. & Jaki, T., 1/11/2019, In: Biometrical Journal. 61, 6, p. 1477-1492 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Loss Functions in Restricted Parameter Spaces and Their Bayesian Applications

    Mozgunov, P., Jaki, T. F. & Gasparini, M., 3/10/2019, In: Journal of Applied Statistics. 46, 13, p. 2314-2337 24 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. E-pub ahead of print

    Bayesian estimation of IVW and MR-Egger models for two-sample Mendelian randomization studies

    Uche-Ikonne, O., Dondelinger, F. & Palmer, T., 21/09/2019, https://doi.org/10.1101/19005868: medRxiv.

    Research output: Working paper

  30. Published

    A novel measure of drug benefit–risk assessment based on Scale Loss Score

    Saint-Hilary, G., Robert, V., Gasparini, M., Jaki, T. F. & Mozgunov, P., 1/09/2019, In: Statistical Methods in Medical Research. 28, 9, p. 2738-2753 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    ‘Cost’ calculations as a barrier to gaining information under the Freedom of Information Act 2000 from the Police in England and Wales

    Kingston, S. E., Elliott, A. & Thomas, T., 1/08/2019, In: Policing and Society: An International Journal of Research and Policy. 29, 7, p. 834-847 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    A Bayesian model to estimate the cutoff and the clinical utility of a biomarker assay

    Vradi, E., Jaki, T. F., Vonk, R. & Brannath, W., 1/08/2019, In: Statistical Methods in Medical Research. 28, 8, p. 2538-2556 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    The effects of sample size on the estimation of regression mixture models

    Jaki, T. F., Kim, M., Lamont, A. E., George, M., Feaster, D. & Van Horn, M. L., 1/04/2019, In: Educational and Psychological Measurement. 79, 2, p. 358-384 27 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Instrumental variable estimation in semi-parametric additive hazards models

    Brueckner, M., Titman, A. C. & Jaki, T. F., 1/03/2019, In: Biometrics. 75, 1, p. 110-120 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    The influence of temperature on nutrient supply and demand: host plant quality is temperature dependent

    Clissold, F. J., Woodman, J. D., Wilson, K. & Simpson, S. J., 1/03/2019, In: INTEGRATIVE AND COMPARATIVE BIOLOGY. 59, Suppl. 1, p. E39-E39 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  36. Published

    The interactive impact of temperature and nutrition on disease resistance

    Clissold, F. J., Woodman, J. D., Wilson, K. & Simpson, S. J., 1/03/2019, In: INTEGRATIVE AND COMPARATIVE BIOLOGY. 59, Suppl. 1, p. E39-E39 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  37. Published

    Quantifying the association between progression-free survival and overall survival in oncology trials using Kendall's tau.

    Weber, E. & Titman, A. C., 28/02/2019, In: Statistics in Medicine. 38, 5, p. 703-719 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    The R package MAMS for designing multi-arm multi-stage clinical trials

    Jaki, T. F., Pallmann, P. S. & Magirr, D., 31/01/2019, In: Journal of Statistical Software. 88, 4, 25 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. E-pub ahead of print

    A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials

    Zheng, H., Hampson, L. V. & Wandel, S., 16/01/2019, In: Statistical Methods in Medical Research. 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Bayesian adaptive methods to incorporate preclinical data into phase I clinical trials

    Zheng, H., 2019, Lancaster University. 176 p.

    Research output: ThesisDoctoral Thesis

  41. Published

    Investigating the association between socio-economic position and stillbirth in Brazil and the UK

    Jones, A., 2019, Lancaster University. 318 p.

    Research output: ThesisDoctoral Thesis

  42. 2018
  43. Published

    An alternative method to analyse the Biomarker-strategy design

    Kunz, C. U., Jaki, T. F. & Stallard, N., 30/12/2018, In: Statistics in Medicine. 37, 30, p. 4636-4651 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Design and estimation in clinical trials with subpopulation selection

    Chiu, Y-D., Koenig, F., Posch, M. & Jaki, T. F., 20/12/2018, In: Statistics in Medicine. 37, 29, p. 4335-4352 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Data collection on trafficking in human beings in the EU: Final report

    Francis, B., Walby, S., Pattinson, B., Elliott, A., Hoti - Llabjani, V., Phoenix, J., Verrall, R. & Peelo, M., 4/12/2018, Luxembourg: European Commission. 272 p.

    Research output: Book/Report/ProceedingsCommissioned report

  46. E-pub ahead of print

    The role of the home environment in neurocognitive development of children living in extreme poverty and with frequent illnesses: a cross-sectional study

    Nampijja, M., Kizindo, R., Apule, B., Lule, S. A., Muhangi, L., Titman, A., Elliott, A., Alcock, K. J. & Lewis, C. N., 3/12/2018, In: Wellcome Open Research. 3, 17 p., 152.

    Research output: Contribution to journalJournal articlepeer-review

  47. E-pub ahead of print

    Randomized dose-escalation designs for drug combination cancer trials with immunotherapy

    Mozgunov, P., Jaki, T. F. & Paoletti, X., 23/10/2018, In: Journal of Biopharmaceutical Statistics. 29, 2, p. 359-377 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Creation of the WHO Indicators of Infant and Young Child Development (IYCD): metadata synthesis across 10 countries

    Lancaster, G. A., McCray, G., Kariger, P., Dua, T., Titman, A., Chandna, J., McCoy, D., Abubakar, A., Hamadani, J. D., Fink, G., Tofail, F., Gladstone, M. & Janus, M., 16/10/2018, In: BMJ Global Health. 3, 5, 15 p., e000747.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Optimal design when outcome values are not missing at random

    Lee, K., Mitra, R. & Biedermann, S., 1/10/2018, In: Statistica Sinica. 28, 4, p. 1821-1838 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. E-pub ahead of print

    Software Application Profile: mrrobust - A Tool For Performing Two-Sample Summary Mendelian Randomization Analyses

    Spiller, W., Davies, N. & Palmer, T. M., 12/09/2018, In: International Journal of Epidemiology.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Performance of different clinical trial designs to evaluate treatments during an epidemic

    Brueckner, M., Titman, A. C., Jaki, T. F., Rojek, A. & Horby, P. W., 11/09/2018, In: PLoS ONE. 13, 9, 19 p., e0203387.

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Bayesian spatial monotonic multiple regression

    Rohrbeck, C., Costain, D. A. & Frigessi, A., 1/09/2018, In: Biometrika. 105, 3, p. 691-707 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    A proposal for a new PhD level curriculum on quantitative methods for drug development

    Jaki, T. F., Gordon, A., Forster, P. S., Bijnens, L., Bornkamp, B., Brannath, W., Fontana, R., Gasparini, M., Hampson, L. V., Jacobs, T., Jones, B., Paoletti, X., Posch, M., Titman, A. C., Vonk, R. & Koenig, F., 09/2018, In: Pharmaceutical Statistics. 17, 5, p. 593-606 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Dose-escalation strategies which utilise subgroup information

    Cotterill, A. & Jaki, T. F., 09/2018, In: Pharmaceutical Statistics. 17, 5, p. 414-436 13 p.

    Research output: Contribution to journalJournal articlepeer-review

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