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Research

Dr Alan Shirras

Formerly at Lancaster University

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  1. 2022
  2. Published

    Reduced Insulin Signalling Targeted to Serotonergic Neurons but Not Other Neuronal Subtypes Extends Lifespan in Drosophila melanogaster

    Dravecz, N., Shaw, T., Davies, I., Brown, C., Ormerod, L., Vu, G., Walker, T., Taank, T., Shirras, A. & Broughton, S., 5/07/2022, In: Frontiers in Aging Neuroscience. 14, 16 p., 893444.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2019
  4. Published

    Loss of angiotensin-converting enzyme-related (ACER) peptidase disrupts behavioural and metabolic responses to diet in Drosophila melanogaster

    Glover, Z., Hodges, M. D. J., Dravecz, N., Cameron, J., Askwith, H., Shirras, A. D. & Broughton, S. J., 25/04/2019, In: Journal of Experimental Biology. 222, 8, 12 p., 194332.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. 2015
  6. Published

    Development of a real-time qPCR assay for quantification of covert baculovirus infections in a major african crop pest

    Graham, R. I., Tummala Munuswamy, Y., Rhodes, G., Cory, J. S., Shirras, A. D., Grzywacz, D. & Wilson, K., 25/08/2015, In: Insects. 6, 3, p. 746-759 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    The Drosophila insulin receptor independently modulates lifespan and locomotor senescence

    Hodges, M., Haji Ismail, M. Z. B., Boylan, M., Achall , R., Shirras, A. & Broughton, S., 28/05/2015, In: PLoS ONE. 10, 5, 21 p., 0125312.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. 2012
  9. Published

    lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2

    Nagy, O., Pal, M., Udvardy, A., Shirras, C. A. M., Boros, I., Shirras, A. D. & Deak, P., 14/03/2012, In: Cell Division. 7, n/a, 16 p., 9.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    A stress-specific calcium signature regulating an ozone-responsive gene expression network in Arabidopsis

    McAinsh, M., Short, E., North, K., Roberts, M., Shirras, A. & Hetherington, A., 2012, In: Plant Journal. 71, 6, p. 948–961 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. 2011
  12. Published

    Cytoplasmic male sterility in Drosophila melanogaster associated with a mitochondrial CYTB variant

    Clancy, D. J., Hime, G. R. & Shirras, A. D., 10/2011, In: Heredity. 107, 4, p. 374-376 3 p.

    Research output: Contribution to Journal/Magazine › Letter › peer-review

  13. Published

    Loss of Angiotensin-converting enzyme-related (ACER) peptidase disrupts night-time sleep in adult Drosophila melanogaster

    Carhan, A., Tang, K., Shirras, C. A., Shirras, A. D. & Isaac, R. E., 02/2011, In: Journal of Experimental Biology. 214, 4, p. 680-686 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. 2010
  15. Published

    Drosophila male sex peptide inhibits siesta sleep and promotes locomotor activity in the post-mated female

    Isaac, R. E., Li, C., Leedale, A. E. & Shirras, A. D., 7/01/2010, In: Proceedings of the Royal Society B: Biological Sciences. 277, 1678, p. 65-70 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. 2009
  17. Published

    Neuropeptidases and the metabolic inactivation of insect neuropeptides

    Isaac, R. E., Bland, N. D. & Shirras, A. D., 15/05/2009, In: General and Comparative Endocrinology. 162, 1, p. 8-17 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Locomotor and geotactic behavior of Drosophila melanogaster over-expressing neprilysin 2

    Bland, N. D., Robinson, P., Thomas, J. E., Shirras, A. D., Turner, A. J. & Isaac, R. E., 03/2009, In: Peptides. 30, 3, p. 571-574 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Increased fragmentation of night-time sleep in Drosophila melanogaster lacking the angiotensin-converting enzyme-related (ACER) peptidase

    Isaac, E., Carhan, A., Tang, K., Shirras, C. & Shirras, A., 2009, In: Journal of Neurogenetics. 23, Supplement 1, p. S70-S70 1 p.

    Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

  20. 2007
  21. Published

    Metabolic inactivation of the circadian transmitter, pigment dispersing factor (PDF), by neprilysin-like peptidases in Drosophila.

    Isaac, R. E., Johnson, E. C., Audsley, N. & Shirras, A. D., 15/12/2007, In: Journal of Experimental Biology. 210, 24, p. 4465-4470 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Male accessory glands of Drosophila melanogaster make a secreted angiotensin I-converting enzyme (ANCE), suggesting a role for the peptide-processing enzyme in seminal fluid.

    Rylett, C. M., Walker, M. J., Howell, G. J., Shirras, A. D. & Isaac, R. E., 15/10/2007, In: Journal of Experimental Biology. 210, 20, p. 3601-3606 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    An unsuspected ecdysteroid/steroid phosphatase activity in the key T-cell regulator, Sts-1: Surprising relationship to insect ecdysteroid phosphate phosphatase

    Davies, L., Anderson, I. P., Turner, P. C., Shirras, A. D., Rees, H. H. & Rigden, D. J., 15/04/2007, In: Proteins: Structure, Function, and Bioinformatics. 67, 3, p. 720-731 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Angiotensin-converting enzyme as a target for the development of novel insect growth regulators.

    Isaac, R. E., Lamango, N. S., Ekbote, U., Taylor, C. A., Hurst, D., Weaver, R. J., Carhan, A., Burnham, S. & Shirras, A. D., 01/2007, In: Peptides. 28, 1, p. 153-162 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Expression of NEP2, a soluble neprilysin-like endopeptidase, during embryogenesis in Drosophila melanogaster.

    Bland, N. D., Thomas, J. E., Audsley, N., Shirras, A. D., Turner, A. J. & Isaac, R. E., 01/2007, In: Peptides. 28, 1, p. 127-135 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. 2006
  27. Published

    Proteomic identification of Drosophila melanogaster male accessory gland proteins, including a pro-cathepsin and a soluble gamma-glutamyl transpeptidase.

    Walker, M. J., Rylett, C. M., Keen, J. N., Audsley, N., Sajid, M., Shirras, A. D. & Isaac, R. E., 2/05/2006, In: Proteome Science. 4, p. 9

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. Published

    Effect of hight rhizospheric calcium on root growth and structure in Arabidopsis.

    Cherukuri, S., McAinsh, M. & Shirras, A., 04/2006, In: Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology. 143, 4 Supp, p. S178

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  29. Published

    Structural diversity of angiotensin-converting enzyme : insights from structure-activity comparisons of two Drosophila enzymes.

    Bingham, R. D., Dive, V., Phillips, S. E. V., Shirras, A. D. & Isaac, R. E., 01/2006, In: FEBS Journal. 273, 2, p. 362-373 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  30. 2005
  31. Published

    Environmental genomics of calcicole-calcifuge physiology.

    Abram, B., Cherukuri, C., Pritchard, S. C., Rodwell, J. S., Shirras, A. D. & McAinsh, M., 07/2005, In: Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology. 141, 3 Supp, p. S276-S277

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  32. Published

    Expression and function of proctolin in Drosophila

    Shirras, A. D., Taylor, C. A. M., Nassel, D. R., Coast, G. M. & Isaac, R. E., 07/2005, In: Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology. 141, 3, p. S159-S160 2 p.

    Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

  33. Published

    Functional genomics of ozone stress in Arabidopsis.

    Short, E., Shirras, A. D. & McAinsh, M., 07/2005, In: Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology. 141, 3 Supp, p. S273-S274

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  34. Published

    Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function.

    Thomas, J. E., Rylett, C. M., Carhan, A., Bland, N. D., Bingham, R. J., Shirras, A. D., Turner, A. J. & Isaac, R. E., 2005, In: Biochemical Journal. 386, 2, p. 357-366 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  35. Published

    The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae.

    Burnham, S., Smith, J. A., Lee, A. J., Isaac, R. E. & Shirras, A. D., 2005, In: BMC Genomics. 6, p. 172

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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