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Dr Cheryl Hawkes

Senior Lecturer in Neuroscience

  1. 2025
  2. E-pub ahead of print

    EZH2 inhibition enhances the activity of Carboplatin in aggressive-variant prostate cancer cell lines

    Latarani, M., Pucci, P., Eccleston, M., Manzo, M., Gangadharannambiar, P., Fischetti, I., Alborelli, I., Mongiardini, V., Mahmood, N., Colombo, M. P., Grimaldi, B., Rigas, S., Akamatsu, S., Hawkes, C., Wang, Y., Jachetti, E. & Crea, F., 29/01/2025, (E-pub ahead of print) In: Epigenomics. 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. 2024
  4. Published

    Progress towards understanding risk factor mechanisms in the development of autism spectrum disorders

    Bryers, A., Hawkes, C. A., Parkin, E. & Dawson, N., 30/10/2024, In: Biochemical Society Transactions. 52, 5, p. 2047-2058 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Both Maternal High-Fat and Post-Weaning High-Carbohydrate Diets Increase Rates of Spontaneous Hepatocellular Carcinoma in Aged-Mouse Offspring

    Holt, D., Contu, L., Wood, A., Chadwick, H., Alborelli, I., Insilla, A. C., Crea, F. & Hawkes, C. A., 22/08/2024, In: Nutrients. 16, 16, 2805.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Clearance of interstitial fluid (ISF) and CSF (CLIC) group‐part of Vascular Professional Interest Area (PIA), updates in 2022‐2023. Cerebrovascular disease and the failure of elimination of Amyloid‐β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy

    Kelly, L., Brown, C., Michalik, D., Hawkes, C. A., Aldea, R., Agarwal, N., Salib, R., Alzetani, A., Ethell, D. W., Counts, S. E., de Leon, M., Fossati, S., Koronyo‐Hamaoui, M., Piazza, F., Rich, S. A., Wolters, F. J., Snyder, H., Ismail, O., Elahi, F. & Proulx, S. T. & 6 others, Verma, A., Wunderlich, H., Haack, M., Dodart, J. C., Mazer, N. & Carare, R. O., 21/02/2024, In: Alzheimer's and Dementia : the journal of the Alzheimer's Association. 20, 2, p. 1421-1435

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 “ ISMRM Imaging Neurofluids Study group” Workshop in Rome

    Agarwal, N., Lewis, L. D., Hirschler, L., Rivera, L. R., Naganawa, S., Levendovszky, S. R., Ringstad, G., Klarica, M., Wardlaw, J., Iadecola, C., Hawkes, C., Carare, R. O., Wells, J., Bakker, E. N. T. P., Kurtcuoglu, V., Bilston, L., Nedergaard, M., Mori, Y., Stoodley, M. & Alperin, N. & 2 others, de Leon, M. & van Osch, M. J. P., 16/01/2024, In: Journal of Magnetic Resonance Imaging. 59, 2, p. 431-449 19 p.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  8. 2023
  9. Published

    A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia

    Sri, S., Greenstein, A., Granata, A., Collcutt, A., Jochems, A. C. C., McColl, B. W., Castro, B. D., Webber, C., Reyes, C. A., Hall, C., Lawrence, C. B., Hawkes, C., Pegasiou-Davies, C.-M., Gibson, C., Crawford, C. L., Smith, C., Vivien, D., McLean, F. H., Wiseman, F. & Brezzo, G. & 37 others, Lalli, G., Pritchard, H. A. T., Markus, H. S., Bravo-Ferrer, I., Taylor, J., Leiper, J., Berwick, J., Gan, J., Gallacher, J., Moss, J., Goense, J., McMullan, L., Work, L., Evans, L., Stringer, M. S., Ashford, M. L. J., Abulfadl, M., Conlon, N., Malhotra, P., Bath, P., Canter, R., Brown, R., Ince, S., Anderle, S., Young, S., Quick, S., Szymkowiak, S., Hill, S., Allan, S., Wang, T., Quinn, T., Procter, T., Farr, T. D., Zhao, X., Yang, Z., Hainsworth, A. H. & Wardlaw, J. M., 31/12/2023, In: Cerebral Circulation - Cognition and Behavior. 5, 100189.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. 2022
  11. Published

    Appetitive Motivation and Associated Neurobiology Change Differentially across the Life Course of Mouse Offspring Exposed to Peri- and Postnatal High Fat Feeding

    Contu, L., Heath, C. J. & Hawkes, C. A., 4/12/2022, In: Nutrients. 14, 23, 21 p., 5161.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression

    Hawkes, C. A., Heath, C. J., Sharp, M. M., Górecki, D. C. & Carare, R. O., 31/08/2022, In: Acta Neuropathologica Communications. 10, 1, 15 p., 127.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Editorial: The Neurovascular Unit as a Potential Biomarker and Therapeutic Target in Cerebrovascular Disease

    Nizari, S., Hawkes, C. A., Hattori, Y. & Mishra, A., 5/05/2022, In: Frontiers in Aging Neuroscience. 14, 2 p., 908716.

    Research output: Contribution to Journal/MagazineEditorialpeer-review

  14. 2021
  15. Published

    Endothelial-derived extracellular vesicles induce cerebrovascular dysfunction in inflammation

    Roig-Carles, D., Willms, E., Fontijn, R. D., Martinez-Pacheco, S., Mäger, I., de Vries, H. E., Hirst, M., Sharrack, B., Male, D. K., Hawkes, C. A. & Romero, I. A., 21/09/2021, In: Pharmaceutics. 13, 9, 1525.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms

    Mather, R. L., Parolia, A., Carson, S. E., Venalainen, E., Roig-Carles, D., Jaber, M., Chu, S. C., Alborelli, I., Wu, R., Lin, D., Nabavi, N., Jachetti, E., Colombo, M. P., Xue, H., Pucci, P., Ci, X., Hawkes, C., Li, Y., Pandha, H. & Ulitsky, I. & 6 others, Marconett, C., Quagliata, L., Jiang, W., Romero, I., Wang, Y. & Crea, F., 31/07/2021, In: Molecular Oncology. 15, 7, p. 1921-1941 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Age-related ultrastructural neurovascular changes in the female mouse cortex and hippocampus

    Frías-Anaya, E., Gromnicova, R., Kraev, I., Rogachevsky, V., Male, D. K., Crea, F., Hawkes, C. A. & Romero, I. A., 31/05/2021, In: Neurobiology of Aging. 101, p. 273-284 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice

    Nizari, S., Wells, J. A., Carare, R. O., Romero, I. A. & Hawkes, C. A., 7/01/2021, In: Acta Neuropathologica Communications. 9, 1, 17 p., 12.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. 2020
  20. Published

    Clearance of interstitial fluid (ISF) and CSF (CLIC) group—part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy

    Carare, R. O., Aldea, R., Agarwal, N., Bacskai, B. J., Bechman, I., Boche, D., Bu, G., Bulters, D., Clemens, A., Counts, S. E., de Leon, M., Eide, P. K., Fossati, S., Greenberg, S. M., Hamel, E., Hawkes, C. A., Koronyo-Hamaoui, M., Hainsworth, A. H., Holtzman, D. & Ihara, M. & 25 others, Jefferson, A., Kalaria, R. N., Kipps, C. M., Kanninen, K. M., Leinonen, V., McLaurin, J. A., Miners, S., Malm, T., Nicoll, J. A. R., Piazza, F., Paul, G., Rich, S. M., Saito, S., Shih, A., Scholtzova, H., Snyder, H., Snyder, P., Thormodsson, F. R., van Veluw, S. J., Weller, R. O., Werring, D. J., Wilcock, D., Wilson, M. R., Zlokovic, B. V. & Verma, A., 3/08/2020, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 12, 1, 7 p., e12053.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Cerebrospinal fluid dynamics modulation by diet and cytokines in rats

    Alimajstorovic, Z., Pascual-Baixauli, E., Hawkes, C. A., Sharrack, B., Loughlin, A. J., Romero, I. A. & Preston, J. E., 10/02/2020, In: Fluids and Barriers of the CNS. 17, 1, 10 p., 10.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. 2019
  23. Published

    Knockout of apolipoprotein A-I decreases parenchymal and vascular β-amyloid pathology in the Tg2576 mouse model of Alzheimer's disease

    Contu, L., Carare, R. O. & Hawkes, C. A., 1/12/2019, In: Neuropathology and Applied Neurobiology. 45, 7, p. 698-714 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Pre- and Post-natal High Fat Feeding Differentially Affects the Structure and Integrity of the Neurovascular Unit of 16-Month Old Male and Female Mice

    Contu, L., Nizari, S., Heath, C. J. & Hawkes, C. A., 2/10/2019, In: Frontiers in Neuroscience. 13, 17 p., 1045.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Immune complex formation impairs the elimination of solutes from the brain: Implications for immunotherapy in Alzheimer's disease

    Carare, R. O., Teeling, J. L., Hawkes, C. A., Püntener, U., Weller, R. O., Nicoll, J. A. R. & Perry, V. H., 9/08/2019, In: Acta Neuropathologica Communications. 2, 1, 48.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  26. Published

    3D reconstruction of the neurovascular unit reveals differential loss of cholinergic innervation in the cortex and hippocampus of the adult mouse brain

    Nizari, S., Carare, R. O., Romero, I. A. & Hawkes, C. A., 4/07/2019, In: Frontiers in Aging Neuroscience. 11, 15 p., 172.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  27. 2018
  28. Published

    Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways

    Albargothy, N. J., Johnston, D. A., MacGregor-Sharp, M., Weller, R. O., Verma, A., Hawkes, C. A. & Carare, R. O., 1/07/2018, In: Acta Neuropathologica. 136, 1, p. 139-152 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  29. Published

    Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology

    Horsburgh, K., Wardlaw, J. M., van Agtmael, T., Allan, S. M., Ashford, M. L. J., Bath, P. M., Brown, R., Berwick, J., Cader, M. Z., Carare, R. O., Davis, J. B., Duncombe, J., Farr, T. D., Fowler, J. H., Goense, J., Granata, A., Hall, C. N., Hainsworth, A. H., Harvey, A. & Hawkes, C. A. & 26 others, Joutel, A., Kalaria, R. N., Kehoe, P. G., Lawrence, C. B., Lockhart, A., Love, S., Macleod, M. R., Macrae, I. M., Markus, H. S., McCabe, C., McColl, B. W., Meakin, P. J., Miller, A., Nedergaard, M., O'Sullivan, M., Quinn, T. J., Rajani, R., Saksida, L. M., Smith, C., Smith, K. J., Touyz, R. M., Trueman, R. C., Wang, T., Williams, A., Williams, S. C. R. & Work, L. M., 30/04/2018, In: Clinical Science. 132, 8, p. 851-868 18 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  30. 2017
  31. Published

    The role of perivascular innervation and neurally mediated vasoreactivity in the pathophysiology of Alzheimer's disease

    Nizari, S., Romero, I. A. & Hawkes, C. A., 1/06/2017, In: Clinical Science. 131, 12, p. 1207-1214 8 p.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  32. Published

    A review of the impact of maternal obesity on the cognitive function and mental health of the offspring

    Contu, L. & Hawkes, C. A., 19/05/2017, In: International Journal of Molecular Sciences. 18, 5, 11 p., 1093.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  33. Published

    Investigating the lymphatic drainage of the brain: Essential skills and tools

    Albargothy, N. J., Sharp, M. M., Gatherer, M., Morris, A., Weller, R. O., Hawkes, C. & Carare, R. O., 7/01/2017, Methods in Molecular Biology. New York: Humana Press Inc., p. 343-365 23 p. (Methods in Molecular Biology; vol. 1559).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  34. 2016
  35. Published

    Vascular basement membranes as pathways for the passage of fluid into and out of the brain

    Morris, A. W. J., Sharp, M. M. G., Albargothy, N. J., Fernandes, R., Hawkes, C. A., Verma, A., Weller, R. O. & Carare, R. O., 1/05/2016, In: Acta Neuropathologica. 131, 5, p. 725-736 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  36. Published

    Automatic detection of the hippocampal region associated with Alzheimer's disease from microscopic images of mice brain

    Albaidhani, T., Hawkes, C., Jassim, S. & Al-Assam, H., 17/04/2016, Mobile Multimedia/Image Processing, Security, and Applications 2016. Jassim, S. A. & Agaian, S. S. (eds.). SPIE, 98690D. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 9869).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  37. Published

    Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet

    Nizari, S., Carare, R. O. & Hawkes, C. A., 25/02/2016, In: Scientific Reports. 6, 10 p., 21981.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  38. Published

    A simulation model of periarterial clearance of amyloid-β from the brain

    Diem, A. K., Tan, M., Bressloff, N. W., Hawkes, C., Morris, A. W. J., Weller, R. O. & Carare, R. O., 12/02/2016, In: Frontiers in Aging Neuroscience. 8, FEB, 11 p., 18.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  39. 2015
  40. Published

    Pathophysiology of lymphatic drainage of the central nervous system: Implications for the pathophysiology of multiple sclerosis

    Weller, R. O., Carare, R. O., Hawkes, C. A. & Galea, I., 20/11/2015, Multiple Sclerosis: A Mechanistic View. Minagar, A. (ed.). Elsevier Inc., p. 479-501 23 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  41. Published

    Are you also what your mother eats? Distinct proteomic portrait as a result of maternal high-fat diet in the cerebral cortex of the adult mouse

    Manousopoulou, A., Woo, J., Woelk, C. H., Johnston, H. E., Singhania, A., Hawkes, C., Garbis, S. D. & Carare, R. O., 6/08/2015, In: International Journal of Obesity. 39, 8, p. 1325-1328 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  42. Published

    Does the difference between PART and Alzheimer’s disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau?

    Weller, R. O., Hawkes, C. A., Carare, R. O. & Hardy, J., 1/05/2015, In: Acta Neuropathologica. 129, 5, p. 763-766 4 p.

    Research output: Contribution to Journal/MagazineLetterpeer-review

  43. Published

    Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring

    Hawkes, C. A., Gentleman, S. M., Nicoll, J. A. & Carare, R. O., 1/03/2015, In: Journal of Pathology. 235, 4, p. 619-631 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  44. Published

    White matter changes in dementia: Role of impaired drainage of interstitial fluid

    Weller, R. O., Hawkes, C. A., Kalaria, R. N., Werring, D. J. & Carare, R. O., 1/01/2015, In: Brain Pathology. 25, 1, p. 63-78 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  45. 2014
  46. Published

    The cerebrovascular basement membrane: Role in the clearance of β-amyloid and cerebral amyloid angiopathy

    Morris, A. W. J., Carare, R. O., Schreiber, S. & Hawkes, C. A., 1/09/2014, In: Frontiers in Aging Neuroscience. 6, SEP, 9 p., 251.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  47. Published

    Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid

    Maki, T., Okamoto, Y., Carare, R. O., Hase, Y., Hattori, Y., Hawkes, C. A., Saito, S., Yamamoto, Y., Terasaki, Y., Ishibashi-Ueda, H., Taguchi, A., Takahashi, R., Miyakawa, T., Kalaria, R. N., Lo, E. H., Arai, K. & Ihara, M., 1/08/2014, In: Annals of Clinical and Translational Neurology. 1, 8, p. 519-533 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  48. Published

    Failure of perivascular drainage of β-amyloid in cerebral amyloid angiopathy

    Hawkes, C. A., Jayakody, N., Johnston, D. A., Bechmann, I. & Carare, R. O., 1/07/2014, In: Brain Pathology. 24, 4, p. 396-403 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  49. Published

    Amyloid and tau in the brain in sporadic Alzheimer's disease: Defining the chicken and the egg

    Hawkes, C. A., Carare, R. O. & Weller, R. O., 1/04/2014, In: Acta Neuropathologica. 127, 4, p. 617-618 2 p.

    Research output: Contribution to Journal/MagazineLetterpeer-review

  50. Published

    Afferent and efferent immunological pathways of the brain. Anatomy, Function and Failure

    Carare, R. O., Hawkes, C. A. & Weller, R. O., 1/02/2014, In: Brain, Behavior, and Immunity. 36, p. 9-14 6 p.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  51. Published

    Hypertension drives parenchymal β-amyloid accumulation in the brain parenchyma

    Bueche, C. Z., Hawkes, C., Garz, C., Vielhaber, S., Attems, J., Knight, R. T., Reymann, K., Heinze, H. J., Carare, R. O. & Schreiber, S., 1/01/2014, In: Annals of Clinical and Translational Neurology. 1, 2, p. 124-129 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  52. 2013
  53. Published

    MK886 reduces cerebral amyloid angiopathy severity in TgCRND8 mice

    Hawkes, C. A., Shaw, J. E., Brown, M., Sampson, A. P., McLaurin, J. & Carare, R. O., 1/12/2013, In: Neurodegenerative Diseases. 13, 1, p. 17-23 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  54. Published

    Stroke-induced opposite and age-dependent changes of vessel-associated markers in co-morbid transgenic mice with Alzheimer-like alterations

    Hawkes, C. A., Michalski, D., Anders, R., Nissel, S., Grosche, J., Bechmann, I., Carare, R. O. & Härtig, W., 1/12/2013, In: Experimental Neurology. 250, p. 270-281 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  55. Published

    Review: Cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a focus on therapy

    Carare, R. O., Hawkes, C. A., Jeffrey, M., Kalaria, R. N. & Weller, R. O., 1/10/2013, In: Neuropathology and Applied Neurobiology. 39, 6, p. 593-611 19 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  56. Published

    Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain

    Hawkes, C. A., Gatherer, M., Sharp, M. M., Dorr, A., Yuen, H. M., Kalaria, R., Weller, R. O. & Carare, R. O., 20/02/2013, In: Aging Cell. 12, 2, p. 224-236 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  57. 2012
  58. Published

    In vivo uptake of β-amyloid by non-plaque associated microglia

    Hawkes, C. A., Deng, L. H., Fenili, D., Nitz, M. & McLaurin, J. A., 26/10/2012, In: Current Alzheimer Research. 9, 8, p. 890-901 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  59. Published

    Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer's disease

    Dorr, A., Sahota, B., Chinta, L. V., Brown, M. E., Lai, A. Y., Ma, K., Hawkes, C. A., McLaurin, J. & Stefanovic, B., 1/10/2012, In: Brain. 135, 10, p. 3039-3050 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  60. Published

    Single-transmembrane domain IGF-II/M6P receptor: Potential interaction with g protein and its association with cholesterol-rich membrane domains

    Amritraj, A., Posse De Chaves, E. I., Hawkes, C., MacDonald, R. G. & Kar, S., 1/10/2012, In: Endocrinology. 153, 10, p. 4784-4798 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  61. Published

    Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele

    Hawkes, C. A., Sullivan, P. M., Hands, S., Weller, R. O., Nicoll, J. A. R. & Carare, R. O., 25/07/2012, In: PLoS ONE. 7, 7, e41636.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  62. 2011
  63. Published

    S1P is associated with protection in human and experimental cerebral malaria

    Finney, C. A. M., Hawkes, C. A., Kain, D. C., Dhabangi, A., Musoke, C., Cserti-Gazdewich, C., Oravecz, T., Conrad Liles, W. & Kain, K. C., 1/07/2011, In: Molecular Medicine. 17, 7-8, p. 717-725 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  64. Published

    Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

    Hawkes, C. A., Härtig, W., Kacza, J., Schliebs, R., Weller, R. O., Nicoll, J. A. & Carare, R. O., 1/04/2011, In: Acta Neuropathologica. 121, 4, p. 431-443 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  65. 2010
  66. Published

    Small molecule β-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease

    Hawkes, C. A., Deng, L. H., Shaw, J. E., Nitz, M. & McLaurin, J., 1/01/2010, In: European Journal of Neuroscience. 31, 2, p. 203-213 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  67. 2009
  68. Published

    Small molecule inhibitors of Aβ-aggregation and neurotoxicity

    Hawkes, C. A., Ng, V. & McLaurin, J., 1/03/2009, In: Drug Development Research. 70, 2, p. 111-124 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  69. Published

    Selective targeting of perivascular macrophages for clearance of β-amyloid in cerebral amyloid angiopathy

    Hawkes, C. A. & McLaurin, J., 27/01/2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 4, p. 1261-1266 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  70. Published

    Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains

    Amritraj, A., Hawkes, C., Phinney, A. L., Mount, H. T., Scott, C. D., Westaway, D. & Kar, S., 1/01/2009, In: Neurobiology of Aging. 30, 1, p. 54-70 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  71. 2008
  72. Published

    Clinical immunotherapy trials in Alzheimer's disease

    Hawkes, C. A. & McLaurin, J. A., 1/09/2008, In: Drug Discovery Today: Therapeutic Strategies. 5, 3, p. 177-183 7 p.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  73. Published

    Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation

    Sun, Y., Zhang, G., Hawkes, C. A., Shaw, J. E., McLaurin, J. A. & Nitz, M., 1/08/2008, In: Bioorganic and Medicinal Chemistry. 16, 15, p. 7177-7184 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  74. 2007
  75. Published

    Analysis of receptor localization in the central nervous system using in vitro and in vivo receptor autoradiography

    Kar, S. & Hawkes, C., 1/12/2007, Handbook of Neurochemistry and Molecular Neurobiology: Practical Neurochemistry Methods. Tsinghua University Press & Springer-Verlag, p. 275-292 18 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  76. Published

    Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria

    Lovegrove, F. E., Gharib, S. A., Patel, S. N., Hawkes, C. A., Kain, K. C. & Liles, W. C., 1/12/2007, In: American Journal of Pathology. 171, 6, p. 1894-1903 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  77. Published

    Immunotherapy as treatment for Alzheimer's disease

    Hawkes, C. A. & McLaurin, J., 1/11/2007, In: Expert Review of Neurotherapeutics. 7, 11, p. 1535-1548 14 p.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  78. Published

    Heterotrimeric G proteins and the single-transmembrane domain IGF-II/M6P receptor: Functional interaction and relevance to cell signaling

    Hawkes, C., Amritraj, A., MacDonald, R. G., Jhamandas, J. H. & Kar, S., 1/06/2007, In: Molecular Neurobiology. 35, 3, p. 329-345 17 p.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  79. Published

    Effect of kainic acid treatment on insulin-like growth factor-2 receptors in the IGF2-deficient adult mouse brain

    Dikkes, P., Hawkes, C., Kar, S. & Lopez, M. F., 2/02/2007, In: Brain Research. 1131, 1, p. 77-87 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  80. 2006
  81. Published

    Up-regulation of cation-independent mannose 6-phosphate receptor and endosomal-lysosomal markers in surviving neurons after 192-IgG-saporin administrations into the adult rat brain

    Hawkes, C., Kabogo, D., Amritraj, A. & Kar, S., 1/10/2006, In: American Journal of Pathology. 169, 4, p. 1140-1154 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  82. Published

    Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model

    McLaurin, J. A., Kierstead, M. E., Brown, M. E., Hawkes, C. A., Lambermon, M. H. L., Phinney, A. L., Darabie, A. A., Cousins, J. E., French, J. E., Lan, M. F., Chen, F., Wong, S. S. N., Mount, H. T. J., Fraser, P. E., Westaway, D. & George-Hyslop, P. S., 1/07/2006, In: Nature Medicine. 12, 7, p. 801-808 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  83. Published

    Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3β

    Li, T., Hawkes, C., Qureshi, H. Y., Kar, S. & Paudel, H. K., 1/03/2006, In: Biochemistry. 45, 10, p. 3134-3145 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  84. Published

    Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimer's disease pathology

    Kar, S., Poirier, J., Guevara, J., Dea, D., Hawkes, C., Robitaille, Y. & Quirion, R., 1/02/2006, In: Neurobiology of Aging. 27, 2, p. 199-210 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  85. Published

    Single transmembrane domain insulin-like growth factor-II/mannose-6- phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway

    Hawkes, C., Jhamandas, J. H., Harris, K. H., Fu, W., MacDonald, R. G. & Kar, S., 11/01/2006, In: Journal of Neuroscience. 26, 2, p. 585-596 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  86. 2005
  87. Published

    Selective loss of basal forebrain cholinergic neurons by 192 IgG-saporin is associated with decreased phosphorylation of Ser9 glycogen synthase kinase-3β

    Hawkes, C., Jhamandas, J. H. & Kar, S., 1/10/2005, In: Journal of Neurochemistry. 95, 1, p. 263-272 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  88. 2004
  89. Published

    The insulin-like growth factor-II/mannose-6-phosphate receptor: Structure, distribution and function in the central nervous system

    Hawkes, C. & Kar, S., 1/03/2004, In: Brain Research Reviews. 44, 2-3, p. 117-140 24 p.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  90. 2003
  91. Published

    Insulin-like growth factor-II/mannose-6-phosphate receptor: Widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype

    Hawkes, C. & Kar, S., 31/03/2003, In: Journal of Comparative Neurology. 458, 2, p. 113-127 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  92. 2002
  93. Published

    Insulin-like growth factor-II/mannose-6-phosphate receptor in the spinal cord and dorsal root ganglia of the adult rat

    Hawkes, C. & Kar, S., 31/01/2002, In: European Journal of Neuroscience. 15, 1, p. 33-39 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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