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Research

Professor Christian Holscher

Formerly at Lancaster University

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  1. Published

    Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice

    Gengler, S., McClean, P. L., McCurtin, R., Gault, V. A. & Holscher, C., 02/2012, In: Neurobiology of Aging. 33, 2, p. 265-276 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    Synaptic plasticity in the hippocampus of an APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice

    Gengler, S., Hamilton, A. & Holscher, C., 22/03/2010, In: PLoS ONE. 5, 3, 10 p., e9764.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    H-1 NMR metabolomics investigation of an Alzheimer's disease (AD) mouse model pinpoints important biochemical disturbances in brain and plasma

    Graham, S. F., Holscher, C., McClean, P., Elliot, C. T. & Green, B. D., 10/2013, In: Metabolomics. 9, 5, p. 974-983 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Investigation of the human brain metabolome to identify potential markers for early diagnosis and therapeutic targets of Alzheimer's disease

    Graham, S. F., Chevallier, O. P., Roberts, D., Hölscher, C., Elliott, C. T. & Green, B. D., 5/02/2013, In: Analytical Chemistry. 85, 3, p. 1803-1811 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Age-associated changes of brain copper, iron, and zinc in Alzheimer's disease and dementia with Lewy bodies

    Graham, S. F., Nasaruddin, M. B., Carey, M., Holscher, C., McGuinness, B., Kehoe, P. G., Love, S., Passmore, P., Elliott, C. T., Meharg, A. A. & Green, B. D., 2014, In: Journal of Alzheimer's Disease. 42, 4, p. 1407-1413 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Metabolic signatures of human Alzheimer's disease (AD): H-1 NMR analysis of the polar metabolome of post-mortem brain tissue

    Graham, S. F., Holscher, C. & Green, B. D., 08/2014, In: Metabolomics. 10, 4, p. 744-753 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Quantitative measurement of [Na+] and [K+] in postmortem human brain tissue indicates disturbances in subjects with Alzheimer's Disease and dementia with Lewy bodies

    Graham, S. F., Nasarauddin, M. B., Carey, M., McGuinness, B., Holscher, C., Kehoe, P. G., Love, S., Passmore, A. P., Elliott, C. T., Meharg, A. & Green, B. D., 2015, In: Journal of Alzheimer's Disease. 44, 3, p. 851-857 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease

    Graham, S. F., Chevallier, O. P., Elliott, C. T., Holscher, C., Johnston, J., McGuinness, B., Kehoe, P. G., Passmore, A. P. & Green, B. D., 24/03/2015, In: PLoS ONE. 10, 3, 16 p., e0119452.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease

    Hamilton, A. & Holscher, C., 17/04/2012, In: Brain Research. 1449, p. 83-93 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain

    Hamilton, A., Patterson, S., Porter, D., Gault, V. A. & Hölscher, C., 04/2011, In: Journal of Neuroscience Research. 89, 4, p. 481-489 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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