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Professor Christian Holscher

Formerly at Lancaster University

  1. Published

    A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinson's disease

    Jalewa, J., Sharma, M. K., Gengler, S. & Hölscher, C., 1/05/2017, In: Neuropharmacology. 117, p. 238-248 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    Neuroprotective effects of glucose-dependent insulinotropic polypeptide in Alzheimer's disease

    Ji, C., Xue, G-F., Li, G., Li, D. & Holscher, C., 01/2016, In: Reviews in the Neurosciences. 27, 1, p. 61-70 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    A novel dual GLP-1 and GIP receptor agonist is neuroprotective in the MPTP mouse model of Parkinson′s disease by increasing expression of BNDF

    Ji, C., Xue, G-F., Lijun, C., Feng, P., Li, D., Li, L., Li, G. & Holscher, C., 1/03/2016, In: Brain Research. 1634, p. 1-11 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    GLP-1/GIP/Gcg三受体激动剂改善3xTg-AD小鼠认知行为和病理特征研究

    Jiao, J-J., Hölscher, C., Li, T., Dong, X-F., Qu, X-S., Cao, Y., Wu, M-N., Wang, Z-J. & Qi, J-S., 25/04/2017, In: Acta Physiologica Sinica. 69, 2, p. 135-145 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Integrating microRNA and messenger RNA expression profiles in a rat model of deep vein thrombosis

    Jin, Q-Q., Sun, J-H., Du, Q-X., Lu, X-J., Zhu, X-Y., Fan, H-L., Holscher, C. & Wang, Y-Y., 10/2017, In: International Journal of Molecular Medicine. 40, 4, p. 1019-1028 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Restoration of cerebral and systemic microvascular architecture in APP/PS1 transgenic mice following treatment with Liraglutide™

    Kelly, P., McClean, P. L., Ackermann, M., Konerding, M. A., Holscher, C. & Mitchell, C. A., 02/2015, In: Microcirculation. 22, 2, p. 133-145 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Comparison of the independent and combined effects of sub-chronic therapy with metformin and a stable GLP-1 receptor agonist on cognitive function, hippocampal synaptic plasticity and metabolic control in high-fat fed mice

    Lennox, R., Porter, D. W., Flatt, P. R., Holscher, C., Irwin, N. & Gault, V. A., 11/2014, In: Neuropharmacology. 86, p. 22-30 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    (Val⁸) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains

    Li, L., Zhang, Z-F., Hölscher, C., Gao, C., Jiang, Y-H. & Liu, Y-Z., 15/01/2012, In: European Journal of Pharmacology. 674, 2-3, p. 280-286 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Hepcidin treatment modulates the expression of divalent metal transporter-1, ceruloplasmin, and ferroportin-1 in the rat cerebral cortex and hippocampus

    Li, L., Hölscher, C., Chen, B-B., Zhang, Z-F. & Liu, Y-Z., 12/2011, In: Biological Trace Element Research. 143, 3, p. 1581-1593 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Neuroprotective effects of a GIP analogue in the MPTP Parkinson's disease mouse model

    Li, Y., Liu, W., Li, L. & Holscher, C., 02/2016, In: Neuropharmacology. 101, p. 255-263 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Neuroprotective role of (Val8)GLP-1-Glu-PAL in an in vitro model of Parkinson’s disease

    Li, L., Liu, K., Holscher, C., Li, G. & Liu, Y-Z., 2016, In: Neural Regeneration Research. 11, 2, p. 326-331 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Therapeutic potential of genipin in central neurodegenerative diseases

    Li, Y., Li, L. & Holscher, C., 10/2016, In: CNS Drugs. 30, 10, p. 889-897 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Incretin-based therapy for type 2 diabetes mellitus is promising for treating neurodegenerative diseases

    Li, Y., Li, L. & Holscher, C., 10/2016, In: Reviews in the Neurosciences. 27, 7, p. 689-711 23 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    D-Ala2-GIP-glu-PAL is neuroprotective in a chronic Parkinson's disease mouse model and increases BNDF expression while reducing neuroinflammation and lipid peroxidation

    Li, Y., Liu, W., Li, L. & Holscher, C., 15/02/2017, In: European Journal of Pharmacology. 797, p. 162-172 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Therapeutic Potential of Baicalein in Alzheimer's Disease and Parkinson's Disease

    Li, Y., Zhao, J. & Holscher, C., 08/2017, In: CNS Drugs. 31, 8, p. 639-652 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    A novel dual GLP-1 and GIP incretin receptor agonist is neuroprotective in a mouse model of Parkinson’s disease by reducing chronic inflammation in the brain

    Lijun, C., Li, D., Feng, P., Li, L., Xue, G., Li, G. & Holscher, C., 13/04/2016, In: NeuroReport. 27, 6, p. 384-391 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease

    Liu, W., Li, Y., Jalewa, J., Saunders-Wood, T., Li, L. & Hölscher, C., 2015, In: European Journal of Pharmacology. 765, p. 284-290 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

    Liu, W., Jalewa, J., Sharma, M., Li, G., Li, L. & Holscher, C., 10/09/2015, In: Neuroscience. 303, p. 42-50 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Neuroprotective effects of geniposide on Alzheimer's disease pathology

    Liu, W., Li, G., Holscher, C. & Li, L., 08/2015, In: Reviews in the Neurosciences. 26, 4, p. 371-383 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    The diabetes drug liraglutide ameliorates aberrant insulin receptor localisation and signalling in parallel with decreasing both amyloid-β plaque and glial pathology in a mouse model of Alzheimer's disease

    Long-Smith, C. M., Manning, S., McClean, P. L., Coakley, M. F., O'Halloran, D. J., Holscher, C. & O'Neill, C., 03/2013, In: NeuroMolecular Medicine. 15, 1, p. 102-114 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-Amyloid oligomers in mice and monkeys

    Lourenco, M. V., Clarke, J. R., Frozza, R. L., Bomfim, T. R., Forny-Germano, L., Batista, A. F., Sathler, L. B., Brito-Moreira, J., Amaral, O. B., Silva, C. A., Freitas-Correa, L., Espírito-Santo, S., Campello-Costa, P., Houzel, J-C., Klein, W. L., Holscher, C., Carvalheira, J. B., Silva, A. M., Velloso, L. A., Munoz, D. P., & 2 othersFerreira, S. T. & De Felice, F. G., 3/12/2013, In: Cell Metabolism. 18, 6, p. 831-843 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Glucagon like peptide-1 receptor agonists as neuroprotective agents for ischemic stroke: a systematic scoping review

    Maskery, M. P., Holscher, C., Jones, S. P., Price, C. I., Strain, W. D., Watkins, C. L., Werring, D. J. & Emsley, H. C. A., 1/01/2021, In: Journal of Cerebral Blood Flow and Metabolism. 41, 1, p. 14-30 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    The diabetes drug Liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease

    McClean, P. L., Parthsarathy, V., Faivre, E. & Holscher, C., 27/04/2011, In: Journal of Neuroscience. 31, 17, p. 6587-6594 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer ‘s disease

    McClean, P. L. & Holscher, C., 2013, In: Neuropharmacology. 76, Part A, p. 57-67 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease

    McClean, P. L., Gault, V. A., Harriott, P. & Hölscher, C., 25/03/2010, In: European Journal of Pharmacology. 630, 1-3, p. 158-162 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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