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Research

Professor Christian Holscher

Formerly at Lancaster University

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  1. Published

    Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice

    Faivre, E., Hamilton, A. & Hölscher, C., 15/01/2012, In: European Journal of Pharmacology. 674, 2-3, p. 294-306 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    Effects of the glucagon-like polypeptide-1 analogue (Val8)GLP-1 on learning, progenitor cell proliferation and neurogenesis in the C57B/16 mouse brain

    McGovern, S. F. J., Hunter, K. & Hölscher, C., 14/09/2012, In: Brain Research. 1473, p. 204-213 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Entropy of city street networks linked to future spatial navigation ability

    Coutrot, A., Manley, E., Goodroe, S., Gahnstrom, C., Filomena, G., Yesiltepe, D., Conroy-Dalton, R., Wiener, J. M., Hölscher, C., Hornberger, M. & Spiers, H. J., 7/04/2022, In: Nature. 604, 7904, p. 104–110 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    First clinical data of the neuroprotective effects of nasal insulin application in patients with Alzheimer's disease

    Hölscher, C., 02/2014, In: Alzheimer's and Dementia. 10, 1 Supplement, p. S33-37 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance

    Porter, D. W., Kerr, B. D., Flatt, P. R., Hölscher, C. & Gault, V. A., 10/2010, In: Diabetes, Obesity and Metabolism. 12, 10, p. 891-899 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    GLP-1 receptor agonists show neuroprotective effects in animal models of diabetes

    Gault, V. A. & Hölscher, C., 02/2018, In: Peptides. 100, p. 101-107 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    GLP-1/GIP/Gcg三受体激动剂改善3xTg-AD小鼠认知行为和病理特征研究

    Jiao, J-J., Hölscher, C., Li, T., Dong, X-F., Qu, X-S., Cao, Y., Wu, M-N., Wang, Z-J. & Qi, J-S., 25/04/2017, In: Acta Physiologica Sinica. 69, 2, p. 135-145 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Glucagon like peptide-1 receptor agonists as neuroprotective agents for ischemic stroke: a systematic scoping review

    Maskery, M. P., Holscher, C., Jones, S. P., Price, C. I., Strain, W. D., Watkins, C. L., Werring, D. J. & Emsley, H. C. A., 1/01/2021, In: Journal of Cerebral Blood Flow and Metabolism. 41, 1, p. 14-30 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide analogues as novel treatments for Alzheimer's and Parkinson's disease

    Hölscher, C., 1/09/2016, In: Cardiovascular Endocrinology . 5, 3, p. 93-98 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease

    McClean, P. L., Gault, V. A., Harriott, P. & Hölscher, C., 25/03/2010, In: European Journal of Pharmacology. 630, 1-3, p. 158-162 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Glucose-dependent insulinotropic polypeptide receptor knockout mice are impaired in learning, synaptic plasticity, and neurogenesis

    Faivre, E., Gault, V. A., Thorens, B. & Hölscher, C., 1/04/2011, In: Journal of Neurophysiology. 105, 4, p. 1574-1580 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease

    Gao, C., Hölscher, C., Liu, Y. & Li, L., 02/2012, In: Reviews in the Neurosciences. 23, 1, p. 1-11 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    H-1 NMR metabolomics investigation of an Alzheimer's disease (AD) mouse model pinpoints important biochemical disturbances in brain and plasma

    Graham, S. F., Holscher, C., McClean, P., Elliot, C. T. & Green, B. D., 10/2013, In: Metabolomics. 9, 5, p. 974-983 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Hepcidin treatment modulates the expression of divalent metal transporter-1, ceruloplasmin, and ferroportin-1 in the rat cerebral cortex and hippocampus

    Li, L., Hölscher, C., Chen, B-B., Zhang, Z-F. & Liu, Y-Z., 12/2011, In: Biological Trace Element Research. 143, 3, p. 1581-1593 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Incretin analogues that have been developed to treat type 2 diabetes hold promise as a novel treatment strategy for Alzheimer's disease

    Hölscher, C., 06/2010, In: Recent Patents on CNS Drug Discovery. 5, 2, p. 109-117 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Incretin-based therapy for type 2 diabetes mellitus is promising for treating neurodegenerative diseases

    Li, Y., Li, L. & Holscher, C., 10/2016, In: Reviews in the Neurosciences. 27, 7, p. 689-711 23 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases

    Hölscher, C., 1/04/2014, In: Biochemical Society Transactions. 42, 2, p. 593-599 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Integrating microRNA and messenger RNA expression profiles in a rat model of deep vein thrombosis

    Jin, Q-Q., Sun, J-H., Du, Q-X., Lu, X-J., Zhu, X-Y., Fan, H-L., Holscher, C. & Wang, Y-Y., 10/2017, In: International Journal of Molecular Medicine. 40, 4, p. 1019-1028 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Intranasal insulin as a treatment for Alzheimer’s Disease: a review of basic research and clinical evidence

    Freiherr, J., Hallschmid, M., Frey, W., Brünner, Y., Chapman, C., Holscher, C., Craft, S., De Felice, F. & Benedict, C., 07/2013, In: CNS Drugs. 27, 7, p. 505-514 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Investigation of the human brain metabolome to identify potential markers for early diagnosis and therapeutic targets of Alzheimer's disease

    Graham, S. F., Chevallier, O. P., Roberts, D., Hölscher, C., Elliott, C. T. & Green, B. D., 5/02/2013, In: Analytical Chemistry. 85, 3, p. 1803-1811 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Levo-tetrahydropalmatine inhibits the acquisition of ketamine-induced conditioned place preference by regulating the expression of ERK and CREB phosphorylation in rats

    Du, Y., Du, L., Cao, J., Holscher, C., Feng, Y., Su, H., Wang, Y. & Yun, K-M., 15/01/2017, In: Behavioural Brain Research. 317, p. 367-373 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Liraglutide and a lipidized analog of prolactin-releasing peptide show neuroprotective effects in a mouse model of β-amyloid pathology

    Holubová, M., Hrubá, L., Popelová, A., Bencze, M., Pražienková, V., Gengler, S., Kratochvílová, H., Haluzík, M., Železná, B., Kuneš, J., Hölscher, C. & Maletínská, L., 01/2019, In: Neuropharmacology. 144, p. 377-387 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Liraglutide Attenuates the Depressive- and Anxiety-like Behaviour in the Corticosterone Induced Depression Model Via Improving Hippocampal Neural Plasticity

    Weina, H., Yuhu, N., Hölscher, C., Birong, L., Feiyu, S. & Le, W., 1/09/2018, In: Brain Research. 1694, p. 55-62 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer ‘s disease

    McClean, P. L. & Holscher, C., 2013, In: Neuropharmacology. 76, Part A, p. 57-67 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Liraglutide improves hippocampal synaptic plasticity associated with increased expression of Mash1 in ob/ob mice

    Porter, W. D., Flatt, P. R., Hölscher, C. & Gault, V. A., 05/2013, In: International Journal of Obesity. 37, 5, p. 678-684 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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