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Dr Christopher Gaffney

Senior Lecturer in Integrative Physiology

  1. 2019
  2. Published

    NemaLife Machine: An automated microfluidic system for whole-life studies in C. elegans

    Anupom, T., Rahman, M., Gupta, S., Edwards, H., Soni, P., LeBlanc, M., Koblah, D., Gaffney, C., Etheridge, T., Szewczyk, N., Driscoll, M. & Vanapalli, S. A., 20/06/2019.

    Research output: Contribution to conference - Without ISBN/ISSN Poster

  3. Published

    Space Race 2.0: Hostile Space

    Gaffney, C., 8/05/2019, Down to Earth.

    Research output: Other contribution

  4. Published

    Our experience with national and international outreach and engagement for #wormsinspace

    Deane, C., Gaffney, C., Etheridge, T., Szewczyk, N. & Phillips, B., 27/04/2019.

    Research output: Contribution to conference - Without ISBN/ISSN Abstract

  5. 2018
  6. Published

    Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of C. elegans and its functional response to drugs

    Hewitt, J., Pollard, A., Lesanpezeshki, L., Deane, C., Gaffney, C. J., Etheridge, T., Szewczyk, N. & Vanapalli, S., 31/12/2018, In: Disease Models & Mechanisms. 11, 11, 13 p., 36137.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Worms in space: why we are launching them

    Gaffney, C. & Phillips, B., 3/12/2018, The Conversation.

    Research output: Other contribution

  8. Published

    C. elegans as a model for understanding spaceflight induced muscle decline

    Pollard, A., Gaffney, C., Deane, C., Cooke, M., Hewitt, J., Phillips, B., Szewczyk, N., Vanapalli, S. & Etheridge, T., 18/06/2018.

    Research output: Contribution to conference - Without ISBN/ISSN Abstractpeer-review

  9. Published

    Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in C. elegans

    Gaffney, C. J., Pollard, A., Barratt, T., Constantin-Teodosiu, D., Greenhaff, P. L. & Szewczyk, N., 2018, In: Aging. 10, 11, p. 3382—3396 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Worms in Space for Outreach on Earth: Space Life Science Activities for the Classroom

    Gaffney, C. J., Pollard, A., Deane, C., Cooke, M., Balsamo, M., Hewitt, J., Vanapalli, S., Szewczyk, N., Etheridge, T. & Phillips, B., 2018, In: Gravitational and Space Research. 6, 2, p. 74-82 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. 2017
  12. Published

    The effect of long-term confinement and the efficacy of exercise countermeasures on muscle strength during a simulated mission to Mars: data from the Mars500 study

    Gaffney, C. J., Fomina, E., Babich, D., Kitov, V., Uskov, K. & Green, D. A., 13/11/2017, In: Sports Medicine - Open. 3, 1, 11 p., 40.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Mitochondria-targeting hydrogen sulfide donors prolong healthspan: lifespan ratio in Caenorhabditis elegans

    Etheridge, T., Gaffney, C., Szewczyk, N., Torregrossa, R., Wood, M. E. & Whiteman, M., 11/2017, In: Free Radical Biology and Medicine. 112, Suppl. 1, p. 51-51 1 p.

    Research output: Contribution to Journal/MagazineMeeting abstractpeer-review

  14. Published

    FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans

    Samms, R. J., Lewis, J. E., Norton, L., Stephens, F. B., Gaffney, C. J., Butterfield, T., Smith, D. P., Cheng, C. C., Perfield, J. W., Adams, A. C., Ebling, F. J. P. & Tsintzas, K., 1/10/2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 10, p. 3806-3813 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Exercise Metabolism in Nonobese Patients with Type 2 Diabetes Following the Acute Restoration of Normoglycaemia

    Gaffney, C. J., Mansell, P., Stephens, F. B., Macdonald, I. A. & Tsintzas, K., 29/05/2017, In: Journal of Diabetes Research. 2017, 8 p., 8248725.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. 2016
  17. Published

    Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development

    Mora-Lorca, J. A., Sáenz-Narciso, B., Gaffney, C. J., Naranjo-Galindo, F. J., Pedrajas, J. R., Guerrero-Gómez, D., Dobrzynska, A., Askjaer, P., Szewczyk, N. J., Cabello, J. & Miranda-Vizuete, A., 07/2016, In: Free Radical Biology and Medicine. 96, p. 446-461 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Degenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle

    Gaffney, C. J., Shephard, F., Chu, J., Baillie, D. L., Rose, A., Constantin-Teodosiu, D., Greenhaff, P. L. & Szewczyk, N. J., 05/2016, In: Journal of Cachexia, Sarcopenia and Muscle. 7, 2, p. 181-192 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. 2015
  20. Published

    The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans

    Etheridge, T., Rahman, M., Gaffney, C. J., Shaw, D., Shephard, F., Magudia, J., Solomon, D. E., Milne, T., Blawzdziewicz, J., Constantin-Teodosiu, D., Greenhaff, P. L., Vanapalli, S. A. & Szewczyk, N. J., 04/2015, In: FASEB Journal. 29, 4, p. 1235-1246 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Unpublished

    The impact of physiological stressors on mitochondrial function in Caenorhabditis elegans and in humans

    Gaffney, C. J., 2015, (Unpublished) University of Nottingham. 281 p.

    Research output: ThesisDoctoral Thesis

  22. 2014
  23. Published

    Methods to assess subcellular compartments of muscle in C. elegans

    Gaffney, C. J., Bass, J. J., Barratt, T. F. & Szewczyk, N. J., 13/11/2014, In: Journal of Visualized Experiments. 93, p. e52043

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases

    Muñoz-Lobato, F., Rodríguez-Palero, M. J., Naranjo-Galindo, F. J., Shephard, F., Gaffney, C. J., Szewczyk, N. J., Hamamichi, S., Caldwell, K. A., Caldwell, G. A., Link, C. D. & Miranda-Vizuete, A., 10/01/2014, In: Antioxidants and Redox Signaling. 20, 2, p. 217-235 19 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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