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Professor David Middleton

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  1. Published

    Average orientation of a fluoroaromatic molecule in lipid bilayers from DFT-informed NMR measurements of 1H-19F dipolar couplings

    Hughes, E., Griffin, J. M., Coogan, M. P. & Middleton, D. A., 21/07/2018, In: Physical Chemistry Chemical Physics. 20, 27, p. 18207-18215 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    Membrane interactions of peptides representing the polybasic regions of three Rho GTPases are sensitive to the distribution of arginine and lysine residues

    Jack, E. R., Madine, J., Lian, L-Y. & Middleton, D. A., 01/2008, In: Molecular Membrane Biology. 25, 1, p. 14-22 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR

    Lau, S., Griffin, J., Hughes, E. & Middleton, D., 14/11/2019, In: Chemical Communications. 55, 88, p. 13287-13290 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Sensitive morphological characterization of oriented high‐density lipoprotein nanoparticles using 31P NMR spectroscopy

    Lau, S. & Middleton, D., 5/10/2020, In: Angewandte Chemie International Edition. 59, 41, p. 18126-18130 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Forthcoming

    Analysis of the orientation of cholesterol in high-density lipoprotein nanodiscs using solid-state NMR

    Lau, S. & Middleton, D., 7/09/2022, (Accepted/In press) In: Physical Chemistry Chemical Physics.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Site-specific identification of an aβ fibril-heparin interaction site by using solid-state NMR spectroscopy

    Madine, J., Pandya, M. J., Hicks, M. R., Rodger, A., Yates, E. A., Radford, S. E. & Middleton, D. A., 21/12/2012, In: Angewandte Chemie International Edition. 51, 52, p. 13140-3 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Fibrils and nanotubes assembled from a modified amyloid-β peptide fragment differ in the packing of the same β-sheet building blocks

    Madine, J., Davies, H. A., Shaw, C., Hamley, I. W. & Middleton, D. A., 21/03/2012, In: Chemical Communications. 48, 24, p. 2976-8 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Comparison of aggregation enhancement and inhibition as strategies for reducing the cytotoxicity of the aortic amyloid polypeptide medin

    Madine, J. & Middleton, D. A., 08/2010, In: June 2002. ISSN 1460-4582. 39, 9, p. 1281-8 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Evaluation of beta-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation

    Madine, J., Wang, X., Brown, D. R. & Middleton, D. A., 17/08/2009, In: June 2002. ISSN 1460-4582. 10, 12, p. 1982-7 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Exploiting a (13)C-labelled heparin analogue for in situ solid-state NMR investigations of peptide-glycan interactions within amyloid fibrils

    Madine, J., Clayton, J. C., Yates, E. A. & Middleton, D. A., 7/06/2009, In: Organic and Biomolecular Chemistry . 7, 11, p. 2414-20 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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