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Professor David Middleton

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  1. Journal article
  2. Published

    The conformation of ATP within the Na,K-ATPase nucleotide site: a statistically constrained analysis of REDOR solid-state NMR data

    Middleton, D. A., Hughes, E. & Esmann, M., 25/07/2011, In: Angewandte Chemie International Edition. 50, 31, p. 7041-4 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    A study of the membrane association and regulatory effect of the phospholemman cytoplasmic domain

    Hughes, E., Whittaker, C. A. P., Barsukov, I. L., Esmann, M. & Middleton, D. A., 04/2011, In: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1808, 4, p. 1021-31 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Solid-state NMR detection of 14N-13C dipolar couplings between amino acid side groups provides constraints on amyloid fibril architecture

    Middleton, D. A., 02/2011, In: June 2002. ISSN 1460-4582. 49, 2, p. 65-9 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Measurement of multiple torsional angles from one-dimensional solid-state NMR spectra: application to the conformational analysis of a ligand in its biological receptor site

    Edwards, R., Madine, J., Fielding, L. & Middleton, D. A., 14/11/2010, In: June 2002. ISSN 1460-4582. 12, 42, p. 13999-4008 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Heparin-derived oligosaccharides interact with the phospholamban cytoplasmic domain and stimulate SERCA function

    Hughes, E., Edwards, R. & Middleton, D. A., 22/10/2010, In: Biochemical and Biophysical Research Communications. 401, 3, p. 370-5 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Comparison of aggregation enhancement and inhibition as strategies for reducing the cytotoxicity of the aortic amyloid polypeptide medin

    Madine, J. & Middleton, D. A., 08/2010, In: June 2002. ISSN 1460-4582. 39, 9, p. 1281-8 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Evaluation of beta-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation

    Madine, J., Wang, X., Brown, D. R. & Middleton, D. A., 17/08/2009, In: June 2002. ISSN 1460-4582. 10, 12, p. 1982-7 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Inhibitors of protein aggregation and toxicity

    Amijee, H., Madine, J., Middleton, D. A. & Doig, A. J., 08/2009, In: Biochemical Society Transactions. 37, Pt 4, p. 692-6 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Structural analysis of uniformly (13)C-labelled solids from selective angle measurements at rotational resonance

    Patching, S. G., Edwards, R. & Middleton, D. A., 08/2009, In: June 2002. ISSN 1460-4582. 199, 2, p. 242-6 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Solid-state NMR studies of adenosine 5'-triphosphate freeze-trapped in the nucleotide site of Na,K-ATPase

    Middleton, D. A., Hughes, E., Fedosova, N. U. & Esmann, M., 20/07/2009, In: June 2002. ISSN 1460-4582. 10, 11, p. 1789-92 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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