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Professor David Middleton

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  1. 2015
  2. Published

    Long-range effects of Na+ binding in Na,K-ATPase reported by ATP

    Middleton, D. A., Fedosova, N. U. & Esmann, M., 1/12/2015, In: Biochemistry. 54, 47, p. 7041-7047 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Comparisons with amyloid-β reveal an aspartate residue that stabilizes fibrils of the aortic amyloid peptide medin

    Davies, H., Madine, J. & Middleton, D., 20/03/2015, In: Journal of Biological Chemistry. 290, p. 7791-7803 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Ligand orientation in a membrane-embedded receptor site revealed by solid-state NMR with paramagnetic relaxation enhancement.

    Whittaker, C., Patching, S., Esmann, M. & Middleton, D., 7/03/2015, In: Organic and Biomolecular Chemistry . 13, 9, p. 2664-2668 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. 2014
  6. Published

    Comparison of the structure and function of phospholamban and the Arginine-14 deficient mutant associated with dilated cardiomyopathy

    Hughes, E. & Middleton, D. A., 16/09/2014, In: PLoS ONE. 9, 9, 10 p., 106746.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Synthesis of bufalin derivatives with inhibitory activity against prostate cancer cells

    Yuan, X.-F., Tian, H.-Y., Li, J., Jin, L., Jiang, S.-T., Liu, K. W.-K., Luo, C., Middleton, D. A., Esmann, M., Ye, W.-C. & Jiang, R.-W., 3/06/2014, In: Natural Product Research. 28, 11, p. 843-847 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Expression and purification of the aortic amyloid polypeptide medin

    Davies, H. A., Wilkinson, M. C., Gibson, R. P. & Middleton, D. A., 06/2014, In: Protein Expression and Purification. 98, p. 32-37 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Structures, chemotaxonomic significance, cytotoxic and Na+, K+-ATPase inhibitory activities of new cardenolides from Asclepias curassavica

    Zhang, R.-R., Tian, H.-Y., Tan, Y.-F., Chung, T.-Y., Sun, X.-H., Xia, X., Ye, W.-C., Middleton, D. A., Fedosova, N., Esmann, M., Tzen, J. T. C. & Jiang, R.-W., 2014, In: Organic and Biomolecular Chemistry . 12, 44, p. 8919-8929 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. 2013
  11. Published

    Heparin promotes the rapid fibrillization of a peptide with low intrinsic amyloidogenicity

    Madine, J., Davies, H. A., Hughes, E. & Middleton, D. A., 17/12/2013, In: Biochemistry. 52, 50, p. 8984-8992 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Insights into the Molecular Architecture of a Peptide Nanotube Using FTIR and Solid-State NMR Spectroscopic Measurements on an Aligned Sample

    Middleton, D. A., Madine, J., Castelletto, V. & Hamley, I. W., 27/09/2013, In: Angewandte Chemie International Edition. 52, 40, p. 10537-10540

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Probing the contacts of a low-affinity substrate with a membrane-embedded transport protein using 1H-13C cross-polarisation magic-angle spinning solid-state NMR

    Patching, S. G., Henderson, P. J. F., Sharples, D. J. & Middleton, D. A., 03/2013, In: Molecular Membrane Biology. 30, 2, p. 129-37 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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