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Ian Wadsworth

Formerly at Lancaster University

  1. Doctoral Thesis
  2. Published

    Bridging the gap: using extrapolation to reduce the experimental burden in children

    Wadsworth, I., 2018, Lancaster University. 254 p.

    Research output: ThesisDoctoral Thesis

  3. Journal article
  4. Published

    Study to evaluate the optimal dose of remifentanil required to ensure apnea during magnetic resonance imaging of the heart under general anesthesia

    Arnold, P., Sanaulla, S., Hampson, L. V., Davis, A., Tan, J., Cowen, R., Kaleem, M., Williams, A., Wadsworth, I. & Jaki, T., 31/05/2021, In: Paediatric Anesthesia. 31, 5, p. 548-556 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Exposure–response modelling approaches for determining optimal dosing rules in children

    Wadsworth, I., Hampson, L. V., Bornkamp, B. & Jaki, T., 1/09/2020, In: Statistical Methods in Medical Research. 29, 9, p. 2583-2602 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    A quantitative framework to inform extrapolation decisions in children

    Wadsworth, I., Hampson, L. V., Jaki, T., Sills, G. J., Marson, A. G. & Appleton, R., 1/02/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 2, p. 515-534 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Extrapolation of efficacy and other data to support the development of new medicines for children: a systematic review of methods

    Wadsworth, I., Hampson, L. V. & Jaki, T. F., 1/02/2018, In: Statistical Methods in Medical Research. 27, 2, p. 398-413 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Clinical drug development in epilepsy revisited: a proposal for a new paradigm streamlined using extrapolation

    Wadsworth, I., Jaki, T. F., Sills, G. J., Appleton, R., Cross, J. H., Marson, A. G., Martland, T., McLellan, A., Smith, P. E. M., Pellock, J. M. & Hampson, L. V., 11/2016, In: CNS Drugs. 30, 11, p. 1011-1017 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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