Home > Research > Researchers > Professor Joanne Knight > Publications

Professor Joanne Knight

Chair in Applied Data Science, Reader in Applied Data Science

  1. Published

    Biological insights from 108 schizophrenia-associated genetic loci

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 24/07/2014, In: Nature. 511, 7510, p. 421-427 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, 01/2017, In: Nature Genetics. 49, p. 27-35 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, 14/06/2018, In: Cell. 173, 7, p. 1705-1715.e16 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

    Schizophrenia Working Group of the Psychiatric Genomics Consortium & Bipolar Disorders Working Group of the Psychiatric Genomics Consortium, 20/06/2017, In: Translational Psychiatry. 7, 6, 9 p., e1155.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

    UK NIHR BioResource Rare Diseases Consortium, UK PAH Cohort Study Consortium, US PAH Biobank Consortium, Rhodes, C. J., Batai, K., Bleda, M., Haimel, M., Southgate, L., Germain, M., Pauciulo, M. W., Hadinnapola, C., Aman, J., Girerd, B., Arora, A., Knight, J., Hanscombe, K. B., Karnes, J. H., Kaakinen, M., Gall, H., Ulrich, A. & 33 others, Harbaum, L., Cebola, I., Ferrer, J., Lutz, K., Swietlik, E. M., Ahmad, F., Amouyel, P., Archer, S. L., Argula, R., Austin, E. D., Badesch, D., Bakshi, S., Barnett, C., Benza, R., Bhatt, N., Bogaard, H. J., Burger, C. D., Chakinala, M., Church, C., Coghlan, J. G., Condliffe, R., Corris, P. A., Danesino, C., Debette, S., Elliott, C. G., Elwing, J., Eyries, M., Fortin, T., Franke, A., Frantz, R. P., Frost, A., Garcia, J. G. N. & Ghio, S., 1/03/2019, In: Lancet Respiratory Medicine. 7, 3, p. 227-238 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

    CommonMind Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium & iPSYCH-GEMS Schizophrenia Working Group, 1/04/2019, In: Nature Genetics. 51, 4, p. 659-674 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

    M.R.C.Psych & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1/08/2019, In: American Journal of Psychiatry. 176, 8, p. 651-660 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia

    Schizophrenia Working Group of the Psychiatric Genomics Consortium 2, 1/08/2019, In: Neuropsychopharmacology. 44, 9, p. 1562-1569 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

    Wellcome Trust Case Control Consortium 2 & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1/04/2019, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 180, 3, p. 223-231 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia

    GROUP Investigators & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1/03/2020, In: Schizophrenia Bulletin. 46, 2, p. 336-344 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    A polygenic resilience score moderates the genetic risk for schizophrenia

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 6/09/2019, In: Molecular Psychiatry. 2019, 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Cross-Disorder Group of the Psychiatric Genomics Consortium. Electronic address: plee0@mgh.harvard.edu, 12/12/2019, In: Cell. 179, 7, p. 1469-1482.e11 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Comparative genetic architectures of schizophrenia in East Asian and European populations

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 31/12/2019, In: Nature Genetics. 51, 12, p. 1670-1678 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

    ADHD Working Group of the Psychiatric Genomics Consortium, 18/12/2019, In: Nature Communications. 10, 1, 12 p., 5765.

    Research output: Contribution to journalJournal articlepeer-review

  15. E-pub ahead of print

    Complement genes contribute sex-biased vulnerability in diverse disorders

    Schizophrenia Working Group of the Psychiatric Genomics Consortium 2, 11/05/2020, In: Nature. 28 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Attention-Deficit Hyperactivity Disorder in the post-genomic era

    Asherson, P., Knight, J. & IMAGE Consortium, 07/2004, In: European Child and Adolescent Psychiatry. 13 , Suppl 1, p. I50-70 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

    Beall, C. M., Cavalleri, G. L., Deng, L., Elston, R. C., Gao, Y., Knight, J., Li, C., Li, J. C., Liang, Y., McCormack, M., Montgomery, H. E., Pan, H., Robbins, P. A., Shianna, K. V., Tam, S. C., Tsering, N., Veeramah, K. R., Wang, W., Wangdui, P., Weale, M. E. & 9 others, Xu, Y., Xu, Z., Yang, L., Zaman, M. J., Zeng, C., Zhang, L., Zhang, X., Zhaxi, P. & Zheng, Y. T., 22/06/2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11459-11464 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 03/2016, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 171B, 2, p. 276-89 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Routinely collected patient data in neurology research: a systematic mapping review

    Biggin, F., Emsley, H. & Knight, J., 27/11/2020, In: BMC Neurology. 20, 9 p., 431.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Variation in waiting times by diagnostic category: an observational study of 1,951 referrals to a neurology outpatient clinic

    Biggin, F., Howcroft, T., Davies, Q., Knight, J. & Emsley, H., 31/05/2021, In: BMJ Neurology Open. 3, 1, 8 p., 000133.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    A genome-wide significant linkage for severe depression on chromosome 3: the depression network study

    Breen, G., Webb, B. T., Butler, A. W., van den Oord, E. J. C. G., Tozzi, F., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., Mors, O., Owen, M. J., Cohen-Woods, S., Perry, J., Galwey, N. W., Upmanyu, R., Craig, I., Lewis, C. M., Ng, M., Brewster, S. & 8 others, Preisig, M., Rietschel, M., Jones, L., Knight, J., Rice, J., Muglia, P., Farmer, A. E. & McGuffin, P., 08/2011, In: American Journal of Psychiatry. 168, 8, p. 840-847 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

    Brookes, K., Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., Anney, R., Franke, B., Gill, M., Ebstein, R., Buitelaar, J., Sham, P., Campbell, D., Knight, J., Andreou, P., Altink, M., Arnold, R., Boer, F., Buschgens, C., Butler, L. & 42 others, Christiansen, H., Feldman, L., Fleischman, K., Fliers, E., Howe-Forbes, R., Goldfarb, A., Heise, A., Gabriëls, I., Korn-Lubetzki, I., Johansson, L., Marco, R., Medad, S., Minderaa, R., Mulas, F., Müller, U., Mulligan, A., Rabin, K., Rommelse, N., Sethna, V., Sorohan, J., Uebel, H., Psychogiou, L., Weeks, A., Barrett, R., Craig, I., Banaschewski, T., Sonuga-Barke, E., Eisenberg, J., Kuntsi, J., Manor, I., McGuffin, P., Miranda, A., Oades, R. D., Plomin, R., Roeyers, H., Rothenberger, A., Sergeant, J., Steinhausen, H-C., Taylor, E., Thompson, M., Faraone, S. V. & Asherson, P., 10/2006, In: Molecular Psychiatry. 11, 10, p. 934-953 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy

    Brookes, K-J., Mill, J., Guindalini, C., Curran, S., Xu, X., Knight, J., Chen, C-K., Huang, Y-S., Sethna, V., Taylor, E., Chen, W., Breen, G. & Asherson, P., 01/2006, In: Archives of General Psychiatry. 63, 1, p. 74-81 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    DNA pooling analysis of ADHD and genes regulating vesicle release of neurotransmitters

    Brookes, K. J., Knight, J., Xu, X. & Asherson, P., 5/11/2005, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 139B, 1, p. 33-37 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 03/2015, In: Nature Genetics. 47, 3, p. 291-295 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children

    Butcher, L. M., Meaburn, E., Knight, J., Sham, P. C., Schalkwyk, L. C., Craig, I. W. & Plomin, R., 15/05/2005, In: Human Molecular Genetics. 14, 10, p. 1315-1325 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Software for generating liability distributions for pedigrees conditional on their observed disease states and covariates

    Campbell, D. D., Sham, P. C., Knight, J., Wickham, H. & Landau, S., 02/2010, In: Genetic Epidemiology. 34, 2, p. 159-170 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Genome-wide mapping of human loci for essential hypertension

    Caulfield, M., Munroe, P., Pembroke, J., Samani, N., Dominiczak, A., Brown, M., Benjamin, N., Webster, J., Ratcliffe, P., O'Shea, S., Papp, J., Taylor, E., Dobson, R., Knight, J., Newhouse, S., Hooper, J., Lee, W., Brain, N., Clayton, D., Lathrop, G. M. & 3 others, Farrall, M., Connell, J. & MRC British Genetics of Hypertension Study, 21/06/2003, In: The Lancet. 361, 9375, p. 2118-2123 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Genes for hypertension

    Caulfield, M., Knight, J., Gardener, G., O’Shea, S. & Monroe, P., 2002, An introduction to vascular biology: from basic science to clinical practice. Hunt, B. J. (ed.). 2nd ed ed. Cambridge: Cambridge University Press

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  30. Published

    DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkage

    Chen, W., Zhou, K., Sham, P., Franke, B., Kuntsi, J., Campbell, D., Fleischman, K., Knight, J., Andreou, P., Arnold, R., Altink, M., Boer, F., Boholst, M. J., Buschgens, C., Butler, L., Christiansen, H., Fliers, E., Howe-Forbes, R., Gabriëls, I., Heise, A. & 30 others, Korn-Lubetzki, I., Marco, R., Medad, S., Minderaa, R., Müller, U. C., Mulligan, A., Psychogiou, L., Rommelse, N., Sethna, V., Uebel, H., McGuffin, P., Plomin, R., Banaschewski, T., Buitelaar, J., Ebstein, R., Eisenberg, J., Gill, M., Manor, I., Miranda, A., Mulas, F., Oades, R. D., Roeyers, H., Rothenberger, A., Sergeant, J., Sonuga-Barke, E., Steinhausen, H-C., Taylor, E., Thompson, M., Faraone, S. V. & Asherson, P., 5/12/2008, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 147B, 8, p. 1450-1460 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences

    Chenoweth, M. J., Ware, J. J., Zhu, A. Z. X., Cole, C. B., Cox, L. S., Nollen, N., Ahluwalia, J. S., Benowitz, N. L., Schnoll, R. A., Hawk, L. W., Cinciripini, P. M., George, T. P., Lerman, C., Knight, J., Tyndale, R. F. & PGRN-PNAT Research Group, 03/2018, In: Addiction. 113, 3, p. 509-523 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    A genome-wide association study of nausea incidence in varenicline-treated cigarette smokers

    Chenoweth, M. J., Lerman, C., Knight, J. & Tyndale, R. F., 31/10/2021, In: Nicotine and Tobacco Research. 23, 10, p. 1805-1809 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans

    Chenoweth, M. J., Cox, L. S., Nollen, N. L., Ahluwalia, J. S., Benowitz, N. L., Lerman, C., Knight, J. & Tyndale, R. F., 1/10/2021, In: Scientific Reports. 11, 1, 12 p., 19572.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Haplotype and linkage disequilibrium analysis to characterise a region in the calcium channel gene CACNA1A associated with idiopathic generalised epilepsy

    Chioza, B., Osei-Lah, A., Nashef, L., Suarez-Merino, B., Wilkie, H., Sham, P., Knight, J., Asherson, P. & Makoff, A. J., 12/2002, In: European Journal of Human Genetics. 10, 12, p. 857-864 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    The Bipolar Association Case-Control Study (BACCS) and meta-analysis: no association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder

    Cohen-Woods, S., Craig, I., Gaysina, D., Gray, J., Gunasinghe, C., Craddock, N., Elkin, A., Jones, L., Kennedy, J., King, N., Korszun, A., Knight, J., Owen, M., Parikh, S., Strauss, J., Sterne, A., Tozzi, F., Perry, J., Muglia, P., Vincent, J. & 2 others, McGuffin, P. & Farmer, A., 5/10/2010, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 153B, 7, p. 1298-1304 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Depression Case Control (DeCC) study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder

    Cohen-Woods, S., Gaysina, D., Craddock, N., Farmer, A., Gray, J., Gunasinghe, C., Hoda, F., Jones, L., Knight, J., Korszun, A., Owen, M. J., Sterne, A., Craig, I. W. & McGuffin, P., 15/04/2009, In: Human Molecular Genetics. 18, 8, p. 1504-1509 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Program report: GENECOUNTING support programs

    Curtis, D., Knight, J. & Sham, P. C., 03/2006, In: Annals of Human Genetics. 70, Pt 2, p. 277-279 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    A new method of linkage analysis using LOD scores for quantitative traits supports linkage of monoamine oxidase activity to D17S250 in the Collaborative Study on the Genetics of Alcoholism pedigrees

    Curtis, D., Knight, J. & Sham, P. C., 09/2005, In: Psychiatric Genetics. 15, 3, p. 181-187 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Investigation into the ability of SNP chipsets and microsatellites to detect association with a disease locus

    Curtis, D., Vine, A. E. & Knight, J., 07/2008, In: Annals of Human Genetics. 72, 4, p. 547-556 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Study of regions of extended homozygosity provides a powerful method to explore haplotype structure of human populations

    Curtis, D., Vine, A. E. & Knight, J., 03/2008, In: Annals of Human Genetics. 72, 2, p. 261-278 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    A simple method for assessing the strength of evidence for association at the level of the whole gene

    Curtis, D., Vine, A. E. & Knight, J., 17/11/2008, In: Advances and Applications in Bioinformatics and Chemistry : AABC. 1, p. 115-120 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    A pragmatic suggestion for dealing with results for candidate genes obtained from genome wide association studies

    Curtis, D., Vine, A. E. & Knight, J., 10/05/2007, In: Genetics. 8, 6 p., 20.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Dopamine genes and pathological gambling in discordant sib-pairs

    da Silva Lobo, D. S., Vallada, H. P., Knight, J., Martins, S. S., Tavares, H., Gentil, V. & Kennedy, J. L., 12/2007, In: Journal of Gambling Studies. 23, 4, p. 421-433 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    The effect of haplotype-block definitions on inference of haplotype-block structure and htSNPs selection

    Ding, K., Zhou, K., Zhang, J., Knight, J., Zhang, X. & Shen, Y., 01/2005, In: Molecular Biology and Evolution. 22, 1, p. 148-159 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Profiling Medical Journal Articles Using a Gene Ontology Semantic Tagger

    El Haj, M., Rayson, P. E., Piao, S. S. & Knight, J., 11/05/2018, LREC 2018, Eleventh International Conference on Language Resources and Evaluation. Calzolari, N., Choukri, K., Cieri, C., Declerck, T., Goggi, S., Hasida, K., Isahara, H., Maegaard, B., Mariani, J., Mazo, H., Moreno, A., Odijk, J., Piperidis, S. & Tokunaga, T. (eds.). European Language Resources Association (ELRA), p. 4593-4597 5 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  46. Published

    Transferability Of Ancestry-Specific And Cross-Ancestry CYP2A6 Activity Genetic Risk Scores In African And European Populations

    El-Boraie, A., Chenoweth, M. J., Pouget, J. G., Benowitz, N. L., Fukunaga, K., Mushiroda, T., Kubo, M., Nollen, N. L., Cox, L. S., Lerman, C., Knight, J. & Tyndale, R. F., 31/10/2021, In: Clinical pharmacology and therapeutics. 110, 4, p. 975-985 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    A Comparison Between Genetics Papers Relating to Immune Disorders and Psychiatric Disorders

    El-Haj, M., Piao, S. S., Rayson, P. E. & Knight, J., 11/09/2017.

    Research output: Contribution to conference - Without ISBN/ISSN Posterpeer-review

  48. Published

    Infrastructure for Semantic Annotation in the Genomics Domain

    El-Haj, M., Rutherford, N., Coole, M., Ezeani, I., Prentice, S., Ide, N., Knight, J., Piao, S., Mariani, J., Rayson, P. & Suderman, K., 11/05/2020, LREC 2020, Twelfth International Conference on Language Resources and Evaluation: LREC'20. Paris: European Language Resources Association (ELRA), p. 6921-6929 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  49. Published

    Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., Karaman, I., Ng, F. L., Evangelou, M., Witkowska, K., Tzanis, E., Hellwege, J. N., Giri, A., Velez Edwards, D. R., Sun, Y. V., Cho, K., Gaziano, J. M. & 31 others, Wilson, P. W. F., Tsao, P. S., Kovesdy, C. P., Esko, T., Mägi, R., Milani, L., Almgren, P., Boutin, T., Debette, S., Ding, J., Giulianini, F., Holliday, E. G., Jackson, A. U., Li-Gao, R., Lin, W-Y., Luan, J., Mangino, M., Oldmeadow, C., Prins, B. P., Qian, Y., Sargurupremraj, M., Shah, N., Surendran, P., Thériault, S., Verweij, N., Willems, S. M., Zhao, J-H., Amouyel, P., Connell, J., Knight, J. & Million Veteran Program, 17/09/2018, In: Nature Genetics. 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Genetic epistasis regulates amyloid deposition in resilient aging

    Felsky, D., Xu, J., Chibnik, L., Schneider, J., Knight, J., Kennedy, J. L., Bennett, D. A., De Jager, P. L. & Voineskos, A. N., 10/2017, In: Alzheimer's and Dementia. 13, 10, p. 1107-1116 10 p.

    Research output: Contribution to journalJournal articlepeer-review

Previous 1 2 3 Next

Back to top