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Professor Joanne Knight

Chair in Applied Data Science, Reader in Applied Data Science

  1. Published

    A genome-wide association study of suicide severity scores in bipolar disorder

    Zai, C. C., Gonçalves, V. F., Tiwari, A. K., Gagliano, S. A., Hosang, G., de Luca, V., Shaikh, S. A., King, N., Chen, Q., Xu, W., Strauss, J., Breen, G., Lewis, C. M., Farmer, A. E., McGuffin, P., Knight, J., Vincent, J. B. & Kennedy, J. L., 06/2015, In: Journal of Psychiatric Research. 65, p. 23-29 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa

    Yilmaz, Z., Kaplan, A. S., Tiwari, A. K., Levitan, R. D., Piran, S., Bergen, A. W., Kaye, W. H., Hakonarson, H., Wang, K., Berrettini, W. H., Brandt, H. A., Bulik, C. M., Crawford, S., Crow, S., Fichter, M. M., Halmi, K. A., Johnson, C. L., Keel, P. K., Klump, K. L., Magistretti, P. & 7 others, Mitchell, J., Strober, M., Thornton, L. M., Treasure, J., Woodside, D. B., Knight, J. & Kennedy, J. L., 08/2014, In: Journal of Psychiatric Research. 55, p. 77-86 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1

    Xu, W., Cohen-Woods, S., Chen, Q., Noor, A., Knight, J., Hosang, G., Parikh, S. V., De Luca, V., Tozzi, F., Muglia, P., Forte, J., McQuillin, A., Hu, P., Gurling, H. M. D., Kennedy, J. L., McGuffin, P., Farmer, A., Strauss, J. & Vincent, J. B., 4/01/2014, In: Journal of Medical Genetics. 15, 13 p., 2.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: no evidence for association

    Xu, X., Knight, J., Brookes, K., Mill, J., Sham, P., Craig, I., Taylor, E. & Asherson, P., 5/04/2005, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 134B, 1, p. 115-118 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Can we accurately classify schizophrenia patients from healthy controls using magnetic resonance imaging and machine learning? A multi-method and multi-dataset study

    Winterburn, J. L., Voineskos, A. N., Devenyi, G. A., Plitman, E., de la Fuente-Sandoval, C., Bhagwat, N., Graff-Guerrero, A., Knight, J. & Chakravarty, M. M., 1/12/2019, In: Schizophrenia Research. 214, p. 3-10 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Predictors of outcome in ulcerative colitis

    Waterman, M., Knight, J., Dinani, A., Xu, W., Stempak, J. M., Croitoru, K., Nguyen, G. C., Cohen, Z., McLeod, R. S., Greenberg, G. R., Steinhart, A. H. & Silverberg, M. S., 09/2015, In: Inflammatory Bowel Diseases. 21, 9, p. 2097-2105 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    CYP2A6 reduced activity gene variants confer reduction in lung cancer risk in African American smokers: findings from two independent populations

    Wassenaar, C. A., Ye, Y., Cai, Q., Aldrich, M. C., Knight, J., Spitz, M. R., Wu, X., Blot, W. J. & Tyndale, R. F., 01/2015, In: Carcinogenesis. 36, 1, p. 99-103 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., Ntalla, I., Surendran, P., Liu, C., Cook, J. P., Kraja, A. T., Drenos, F., Loh, M., Verweij, N., Marten, J., Karaman, I., Lepe, M. P. S., O'Reilly, P. F., Knight, J., Snieder, H. & 31 others, Kato, N., He, J., Tai, E. S., Said, M. A., Porteous, D., Alver, M., Poulter, N., Farrall, M., Gansevoort, R. T., Padmanabhan, S., Mägi, R., Stanton, A., Connell, J., Bakker, S. J. L., Metspalu, A., Shields, D. C., Thom, S., Brown, M., Sever, P., Esko, T., Hayward, C., van der Harst, P., Saleheen, D., Chowdhury, R., Chambers, J. C., Chasman, D. I., Chakravarti, A., Newton-Cheh, C., Lindgren, C. M., Levy, D. & International Consortium of Blood Pressure (ICBP) 1000G Analyses, 20/02/2017, In: Nature Genetics. 49, p. 403-415 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS

    Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, 01/2016, In: PLoS Genetics. 12, 1, 22 p., e1005803.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Late-onset epilepsy predicts stroke: Systematic review and meta-analysis

    Wall, J., Knight, J. & Emsley, H. C. A., 1/02/2021, In: Epilepsy and Behavior. 115, 6 p., 107634.

    Research output: Contribution to journalReview articlepeer-review

  11. Published

    Modeling linkage disequilibrium increases accuracy of polygenic risk scores

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study, 1/10/2015, In: American Journal of Human Genetics. 97, 4, p. 576-592 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Application of multi-locus analytical methods to identify interacting loci in case-control studies

    Vermeulen, S. H. H. M., Den Heijer, M., Sham, P. C. & Knight, J., 09/2007, In: Annals of Human Genetics. 71, 5, p. 689-700 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Common variants in DGKK are strongly associated with risk of hypospadias

    van der Zanden, L. F. M., van Rooij, I. A. L. M., Feitz, W. F. J., Knight, J., Donders, A. R. T., Renkema, K. Y., Bongers, E. M. H. F., Vermeulen, S. H. H. M., Kiemeney, L. A. L. M., Veltman, J. A., Arias-Vásquez, A., Zhang, X., Markljung, E., Qiao, L., Baskin, L. S., Nordenskjöld, A., Roeleveld, N., Franke, B. & Knoers, N. V. A. M., 01/2011, In: Nature Genetics. 43, 1, p. 48-50 3 p.

    Research output: Contribution to journalLetterpeer-review

  14. Published

    Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

    Tsoi, L. C., Spain, S. L., Ellinghaus, E., Stuart, P. E., Capon, F., Knight, J., Tejasvi, T., Kang, H. M., Allen, M. H., Lambert, S., Stoll, S. W., Weidinger, S., Gudjonsson, J. E., Koks, S., Kingo, K., Esko, T., Das, S., Metspalu, A., Weichenthal, M., Enerback, C. & 13 others, Krueger, G. G., Voorhees, J. J., Chandran, V., Rosen, C. F., Rahman, P., Gladman, D. D., Reis, A., Nair, R. P., Franke, A., Barker, J. N. W. N., Abecasis, G. R., Trembath, R. C. & Elder, J. T., 5/05/2015, In: Nature Communications. 6, 8 p., 7001.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Tsoi, L. C., Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, J. E., Kang, H. M., Allen, M. H., McManus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Ståhle, M., Burden, A. D., Smith, C. H., Cork, M. J. & 31 others, Estivill, X., Bowcock, A. M., Krueger, G. G., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, F. O., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, R. D., Vukcevic, D., Spencer, C. C. A., Deloukas, P., Mrowietz, U., Schreiber, S., Weidinger, S., Koks, S., Kingo, K., Esko, T., Metspalu, A., Lim, H. W., Voorhees, J. J. & Collaborative Association Study of Psoriasis (CASP), 12/2012, In: Nature Genetics. 44, 12, p. 1341-1348 8 p.

    Research output: Contribution to journalLetterpeer-review

  16. Published

    Genetic association analysis of N-methyl-d-aspartate receptor subunit gene GRIN2B and clinical response to clozapine

    Taylor, D. L., Tiwari, A. K., Lieberman, J. A., Potkin, S. G., Meltzer, H. Y., Knight, J., Remington, G., Müller, D. J. & Kennedy, J. L., 03/2016, In: Human Psychopharmacology: Clinical and Experimental. 31, 2, p. 121-134 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

    Strange, A., Capon, F., Spencer, C. C. A., Knight, J., Weale, M. E., Allen, M. H., Barton, A., Band, G., Bellenguez, C., Bergboer, J. G. M., Blackwell, J. M., Bramon, E., Bumpstead, S. J., Casas, J. P., Cork, M. J., Corvin, A., Deloukas, P., Dilthey, A., Duncanson, A., Edkins, S. & 31 others, Estivill, X., Fitzgerald, O., Freeman, C., Giardina, E., Gray, E., Hofer, A., Hüffmeier, U., Hunt, S. E., Irvine, A. D., Jankowski, J., Kirby, B., Langford, C., Lascorz, J., Leman, J., Leslie, S., Mallbris, L., Markus, H. S., Mathew, C. G., McLean, W. H. I., McManus, R., Mössner, R., Moutsianas, L., Naluai, A. T., Nestle, F. O., Novelli, G., Onoufriadis, A., Palmer, C. N. A., Perricone, C., Pirinen, M., Plomin, R. & Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2, 11/2010, In: Nature Genetics. 42, 11, p. 985-990 6 p.

    Research output: Contribution to journalLetterpeer-review

  18. Published

    Genetic Markers of Human Evolution Are Enriched in Schizophrenia

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, 15/08/2016, In: Biological Psychiatry. 80, 4, p. 284-92 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

    Simpson, C. L., Lemmens, R., Miskiewicz, K., Broom, W. J., Hansen, V. K., van Vught, P. W. J., Landers, J. E., Sapp, P., Van Den Bosch, L., Knight, J., Neale, B. M., Turner, M. R., Veldink, J. H., Ophoff, R. A., Tripathi, V. B., Beleza, A., Shah, M. N., Proitsi, P., Van Hoecke, A., Carmeliet, P. & 10 others, Horvitz, H. R., Leigh, P. N., Shaw, C. E., van den Berg, L. H., Sham, P. C., Powell, J. F., Verstreken, P., Brown, R. H., Robberecht, W. & Al-Chalabi, A., 1/02/2009, In: Human Molecular Genetics. 18, 3, p. 472-481 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays

    Simpson, C. L., Knight, J., Butcher, L. M., Hansen, V. K., Meaburn, E., Schalkwyk, L. C., Craig, I. W., Powell, J. F., Sham, P. C. & Al-Chalabi, A., 2005, In: Nucleic Acids Research. 33, 3, e25.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Haplotype association analysis of discrete and continuous traits using mixture of regression models

    Sham, P. C., Rijsdijk, F. V., Knight, J., Makoff, A., North, B. & Curtis, D., 03/2004, In: Behavior Genetics. 34, 2, p. 207-214 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Schizophrenia risk from complex variation of complement component 4

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 11/02/2016, In: Nature. 530, 7589, p. 177-183 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    APOE-ɛ4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

    Saeed Mirza, S., Saeed, U., Knight, J., Ramirez, J., Stuss, D., Keith, J., Nestor, S. M., Yu, D., Swardfager, W., Rogaeva, E., George-Hyslop, P. S., Black, S. E. & Masellis, M., 5/11/2019, In: Neurology. 93, 19, p. e1807-e1819 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies

    Saeed, U., Mirza, S. S., MacIntosh, B. J., Herrmann, N., Keith, J., Ramirez, J., Nestor, S. M., Yu, Q., Knight, J., Swardfager, W., Potkin, S. G., Rogaeva, E., George-Hyslop, P. S., Black, S. E. & Masellis, M., 09/2018, In: Alzheimer's and Dementia. 14, 9, p. 1137-1147 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Differential methylation of the X-chromosome is a possible source of discordance for bipolar disorder female monozygotic twins

    Rosa, A., Picchioni, M. M., Kalidindi, S., Loat, C. S., Knight, J., Toulopoulou, T., Vonk, R., van der Schot, A. C., Nolen, W., Kahn, R. S., McGuffin, P., Murray, R. M. & Craig, I. W., 5/06/2008, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 147B, 4, p. 459-462 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium Mendelian randomization study

    Prins, B. P., Abbasi, A., Wong, A., Vaez, A., Nolte, I., Franceschini, N., Stuart, P. E., Guterriez Achury, J., Mistry, V., Bradfield, J. P., Valdes, A. M., Bras, J., Shatunov, A., Lu, C., Han, B., Raychaudhuri, S., Bevan, S., Mayes, M. D., Tsoi, L. C., Evangelou, E. & 28 others, Nair, R. P., Grant, S. F. A., Polychronakos, C., Radstake, T. R. D., van Heel, D. A., Dunstan, M. L., Wood, N. W., Al-Chalabi, A., Dehghan, A., Hakonarson, H., Markus, H. S., Elder, J. T., Knight, J., Arking, D. E., Spector, T. D., Koeleman, B. P. C., van Duijn, C. M., Martin, J., Morris, A. P., Weersma, R. K., Wijmenga, C., Munroe, P. B., Perry, J. R. B., Pouget, J. G., Jamshidi, Y., Snieder, H., Alizadeh, B. Z. & PAGE Consortium, 21/06/2016, In: PLoS Medicine. 13, 6, 29 p., e1001976.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

    Prescott, N. J., Lehne, B., Stone, K., Lee, J. C., Taylor, K., Knight, J., Papouli, E., Mirza, M. M., Simpson, M. A., Spain, S. L., Lu, G., Fraternali, F., Bumpstead, S. J., Gray, E., Amar, A., Bye, H., Green, P., Chung-Faye, G., Hayee, BH., Pollok, R. & 10 others, Satsangi, J., Parkes, M., Barrett, J. C., Mansfield, J. C., Sanderson, J., Lewis, C. M., Weale, M. E., Schlitt, T., Mathew, C. G. & UK IBD Genetics Consortium, 11/02/2015, In: PLoS Genetics. 11, 2, e1004955.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Problematising Characteristicness: A Biomedical Association Case Study

    Prentice, S., Knight, J., Rayson, P., El-Haj, M. & Rutherford, N., 31/08/2021, In: International Journal of Corpus Linguistics. 26, 3, p. 305-335 31 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Forthcoming

    A Domain Based Approach to Semantic Lexicon Expansion

    Prentice, S., Rayson, P., Knight, J., El-Haj, M. & Elstein, S., 4/11/2021, (Accepted/In press) In: International Journal of Lexicography.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Genome-wide association studies suggest limited immune gene enrichment in schizophrenia compared to 5 autoimmune diseases

    Pouget, J. G., Gonçalves, V. F., Spain, S. L., Finucane, H. K., Raychaudhuri, S., Kennedy, J. L., Knight, J. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 09/2016, In: Schizophrenia Bulletin. 42, 5, p. 1176-1184 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Investigation of TSPO variants in schizophrenia and antipsychotic treatment outcomes

    Pouget, J. G., Gonçalves, V. F., Nurmi, E. L., Laughlin, C. P., Mallya, K. S., McCracken, J. T., Aman, M. G., McDougle, C. J., Scahill, L., Misener, V. L., Tiwari, A. K., Zai, C. C., Brandl, E. J., Felsky, D., Leung, A. Q., Lieberman, J. A., Meltzer, H. Y., Potkin, S. G., Niedling, C., Steimer, W. & 4 others, Leucht, S., Knight, J., Müller, D. J. & Kennedy, J. L., 01/2015, In: Pharmacogenomics. 16, 1, p. 5-22 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

    Pouget, J. G., Han, B., Wu, Y., Mignot, E., Ollila, H. M., Barker, J., Spain, S., Dand, N., Trembath, R., Martin, J., Mayes, M. D., Bossini-Castillo, L., López-Isac, E., Jin, Y., Santorico, S. A., Spritz, R. A., Hakonarson, H., Polychronakos, C., Raychaudhuri, S., Knight, J. & 1 others, Schizophrenia Working Group of the Psychiatric Genomics Consortium, 15/10/2019, In: Human Molecular Genetics. 28, 20, p. 3498-3513 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Gene prioritization for imaging genetics studies using gene ontology and a stratified false discovery rate approach

    Patel, S., Park, M. T. M., Chakravarty, M. M., Knight, J. & Alzheimer's Disease Neuroimaging Initiative, 7/04/2016, In: Frontiers in Neuroinformatics. 10, 13 p., 14.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Heritability of hippocampal subfield volumes using a twin and non-twin siblings design

    Patel, S., Park, M. T. M., Devenyi, G. A., Patel, R., Masellis, M., Knight, J. & Chakravarty, M. M., 09/2017, In: Human Brain Mapping. 38, 9, p. 4337-4352 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Heritability estimates of cortical anatomy: The influence and reliability of different estimation strategies

    Patel, S., Patel, R., Park, M. T. M., Masellis, M., Knight, J. & Chakravarty, M. M., 09/2018, In: NeuroImage. 178, p. 78-91 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis

    Onoufriadis, A., Simpson, M. A., Pink, A. E., Di Meglio, P., Smith, C. H., Pullabhatla, V., Knight, J., Spain, S. L., Nestle, F. O., Burden, A. D., Capon, F., Trembath, R. C. & Barker, J. N. W. N., 9/09/2011, In: American Journal of Human Genetics. 89, 3, p. 432-437 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Association of the serotonin transporter gene, neuroticism and smoking behaviours

    O'Gara, C., Knight, J., Stapleton, J., Luty, J., Neale, B., Nash, M., Heuzo-Diaz, P., Hoda, F., Cohen, S., Sutherland, G., Collier, D., Sham, P., Ball, D., McGuffin, P. & Craig, I., 2008, In: Journal of Human Genetics . 53, 3, p. 239-246 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Investigation of the ability of haplotype association and logistic regression to identify associated susceptibility loci

    North, B. V., Sham, P. C., Knight, J., Martin, E. R. & Curtis, D., 11/2006, In: Annals of Human Genetics. 70, 6, p. 893-906 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    NADPH oxidase (CYBA) and FcgammaR polymorphisms as risk factors for aggressive periodontitis: a case-control association study

    Nibali, L., Parkar, M., Brett, P., Knight, J., Tonetti, M. S. & Griffiths, G. S., 08/2006, In: Journal of Clinical Periodontology. 33, 8, p. 529-539 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Age at first birth in women is genetically associated with increased risk of schizophrenia

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 5/07/2018, In: Scientific Reports. 8, 1, 14 p., 10168.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 7/06/2018, In: American Journal of Human Genetics. 102, 6, p. 1185-1194 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris

    Navarini, A. A., Simpson, M. A., Weale, M., Knight, J., Carlavan, I., Reiniche, P., Burden, D. A., Layton, A., Bataille, V., Allen, M., Pleass, R., Pink, A., Creamer, D., English, J., Munn, S., Walton, S., Willis, C., Déret, S., Voegel, J. J., Spector, T. & 4 others, Smith, C. H., Trembath, R. C., Barker, J. N. W. N. & Acne Genetic Study Group, 13/06/2014, In: Nature Communications. 5, 6 p., 4020.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    CEREBRAL PERFUSION AS AN IMAGING BIOMARKER OF PRESYMPTOMATIC GENETIC FRONTOTEMPORAL DEMENTIA: PRELIMINARY RESULTS FROM THE GENETIC FRONTOTEMPORAL DEMENTIA INITIATIVE (GENFI)

    Mutsaerts, H. J. M. M. & Knight, J., 07/2016, In: Alzheimer's and Dementia. 12, 7 Suppl., p. P409-P411 3 p.

    Research output: Contribution to journalMeeting abstract

  44. Published

    1990-2000: progress in determining high blood pressure genes

    Munroe, P. B., Knight, J. & Caulfield, M. J., 05/2000, In: Annals of the Academy of Medicine, Singapore. 29, 3, p. 357-363 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP-25, and 5HT1B

    Mill, J., Xu, X., Ronald, A., Curran, S., Price, T., Knight, J., Craig, I., Sham, P., Plomin, R. & Asherson, P., 5/02/2005, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 133B, 1, p. 68-73 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Haplotype analysis of SNAP-25 suggests a role in the aetiology of ADHD

    Mill, J., Richards, S., Knight, J., Curran, S., Taylor, E. & Asherson, P., 08/2004, In: Molecular Psychiatry. 9, 8, p. 801-810 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

    Project MinE GWAS Consortium & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 21/03/2017, In: Nature Communications. 8, 12 p., 14774.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Whole genome linkage scan of recurrent depressive disorder from the depression network study

    McGuffin, P., Knight, J., Breen, G., Brewster, S., Boyd, P. R., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., Mors, O., Owen, M. J., Perry, J., Preisig, M., Reich, T., Rice, J., Rietschel, M., Jones, L., Sham, P. & Farmer, A. E., 15/11/2005, In: Human Molecular Genetics. 14, 22, p. 3337-3345 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Homing in on depression genes

    McGuffin, P., Cohen, S. & Knight, J., 02/2007, In: American Journal of Psychiatry. 164, 2, p. 195-197 3 p.

    Research output: Contribution to journalEditorialpeer-review

  50. Published

    Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson's disease: a pharmacogenetic study

    Masellis, M., Collinson, S., Freeman, N., Tampakeras, M., Levy, J., Tchelet, A., Eyal, E., Berkovich, E., Eliaz, R. E., Abler, V., Grossman, I., Fitzer-Attas, C., Tiwari, A., Hayden, M. R., Kennedy, J. L., Lang, A. E., Knight, J. & ADAGIO investigators, 07/2016, In: Brain. 139, 7, p. 2050-2062 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Unraveling DNA sequence to identify cerebral indicators of dementia risk

    Masellis, M. & Knight, J., 16/01/2018, In: Neurology. 90, 3, p. 109 1 p.

    Research output: Contribution to journalComment/debate

  52. Published

    Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

    Schizophrenia Working Group of Psychiatric Genomics Consortium, 12/2015, In: Nature Genetics. 47, 12, p. 1385-1392 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Addiction-related genes in gambling disorders: new insights from parallel human and pre-clinical models

    Lobo, D. S. S., Aleksandrova, L., Knight, J., Casey, D. M., el-Guebaly, N., Nobrega, J. N. & Kennedy, J. L., 08/2015, In: Molecular Psychiatry. 20, 8, p. 1002-1010 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 06/2018, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 177, 4, p. 454-467 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Introduction to genetic association studies

    Lewis, C. M. & Knight, J., 03/2012, In: Cold Spring Harbor Protocols. 2012, 3, p. 297-306 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 26/06/2016, In: Schizophrenia Bulletin. 43, 3, p. 654-664 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Complex host genetics influence the microbiome in inflammatory bowel disease

    Knights, D., Silverberg, M. S., Weersma, R. K., Gevers, D., Dijkstra, G., Huang, H., Tyler, A. D., van Sommeren, S., Imhann, F., Stempak, J. M., Huang, H., Vangay, P., Al-Ghalith, G. A., Russell, C., Sauk, J., Knight, J., Daly, M. J., Huttenhower, C. & Xavier, R. J., 2/12/2014, In: Genome Biology. 6, 12, 11 p., 107.

    Research output: Contribution to journalJournal articlepeer-review

  58. Published

    Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis

    Knight, J., Spain, S. L., Capon, F., Hayday, A., Nestle, F. O., Clop, A., Barker, J. N. W. N., Weale, M. E., Trembath, R. C. & Wellcome Trust Case Control Consortium, 1/12/2012, In: Human Molecular Genetics. 21, 23, p. 5185-5192 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published

    Human chromosome 17 in essential hypertension

    Knight, J., Munroe, P. B., Pembroke, J. C. & Caulfield, M. J., 03/2003, In: Annals of Human Genetics. 67, 2, p. 193-206 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans

    Knight, J., Gardner, G. T., Clark, A. J. & Caulfield, M. J., 06/2000, In: Journal of Human Hypertension. 14, 6, p. 385-387 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  61. Published

    CLUMPHAP: a simple tool for performing haplotype-based association analysis

    Knight, J., Curtis, D. & Sham, P. C., 09/2008, In: Genetic Epidemiology. 32, 6, p. 539-545 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  62. Published

    Design and analysis of association studies using pooled DNA from large twin samples

    Knight, J. & Sham, P., 09/2006, In: Behavior Genetics. 36, 5, p. 665-677 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  63. Published

    Mapping loci influencing blood pressure in the Framingham pedigrees using model-free LOD score analysis of a quantitative trait

    Knight, J., North, B. V., Sham, P. C. & Curtis, D., 31/12/2003, In: Genetics. 4 , Suppl. 1, 4 p., S74.

    Research output: Contribution to journalJournal articlepeer-review

  64. Published

    Using functional annotation for the empirical determination of Bayes Factors for genome-wide association study analysis

    Knight, J., Barnes, M. R., Breen, G. & Weale, M. E., 27/04/2011, In: PLoS ONE. 6, 4, 8 p., e14808.

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    An investigation of candidate regions for association with bipolar disorder

    Knight, J., Rochberg, N. S., Saccone, S. F., Nurnberger, J. I., Rice, J. P. & NIMH Genetics Initiative Bipolar Disorder Consortium, 5/10/2010, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 153B, 7, p. 1292-1297 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    A comparison of association statistics between pooled and individual genotypes

    Knight, J., Saccone, S. F., Zhang, Z., Ballinger, D. G. & Rice, J. P., 03/2009, In: Human Heredity. 67, 4, p. 219-225 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    A survey of current software for genetic power calculations

    Knight, J., 2/03/2004, In: BMC Genomics. 1, 3, p. 225-227 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    Regional multi-locus association models

    Knight, J., Sham, P., Shaun, P. & Neale, B., 2007, Statistical genetics: gene mapping through linkage and association. Neale, B., Ferreira, M., Medland, S. & Posthuma, D. (eds.). London: Taylor and Francis

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  69. Published

    Connected Health Cities – Lancaster – the north west coast and beyond

    Knight, J. & King, N. S., 23/04/2018, In: Morecambe Bay Medical Journal. 7, 12, p. 310-310 1 p.

    Research output: Contribution to journalJournal article

  70. Published

    IBD genetic risk profile in healthy first-degree relatives of Crohn's disease patients

    Kevans, D., Silverberg, M. S., Borowski, K., Griffiths, A., Xu, W., Onay, V., Paterson, A. D., Knight, J., Croitoru, K. & GEM Project, 02/2016, In: Journal of Crohn's and Colitis. 10, 2, p. 209-215 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  71. Published

    COVID-19 exposes the urgent need for coding of outpatient neurology episodes

    Kemp, M., Biggin, F., Dayanandan, R., Knight, J. & Emsley, H. C. A., 31/08/2020, In: BMJ Neurology Open. 2, 2, 2 p., e000080.

    Research output: Contribution to journalEditorialpeer-review

  72. Published

    No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 28/10/2016, In: PLoS Genetics. 12, 10, 20 p., e1006343.

    Research output: Contribution to journalJournal articlepeer-review

  73. Published

    A modelling framework for developing early warning systems of COPD emergency admissions

    Johnson, O., Knight, J. & Giorgi, E., 1/02/2021, In: Spatial and Spatio-temporal Epidemiology. 36, 9 p., 100392.

    Research output: Contribution to journalJournal articlepeer-review

  74. Published

    Fine-mapping inflammatory bowel disease loci to single-variant resolution

    Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D'Amato, M., Deffontaine, V., Dmitrieva, J., Docampo, E., Elansary, M., Farh, K. K-H., Franke, A., Gori, A-S., Goyette, P., Halfvarson, J. & 27 others, Haritunians, T., Knight, J., Lawrance, I. C., Lees, C. W., Louis, E., Mariman, R., Meuwissen, T., Mni, M., Momozawa, Y., Parkes, M., Spain, S. L., Théâtre, E., Trynka, G., Satsangi, J., van Sommeren, S., Vermeire, S., Xavier, R. J., Weersma, R. K., Duerr, R. H., Mathew, C. G., Rioux, J. D., McGovern, D. P. B., Cho, J. H., Georges, M., Daly, M. J., Barrett, J. C. & International Inflammatory Bowel Disease Genetics Consortium, 13/07/2017, In: Nature. 547, 7662, p. 173-178 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  75. Published

    Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 16/02/2016, In: Frontiers in Genetics. 7, 13 p., 15.

    Research output: Contribution to journalJournal articlepeer-review

  76. Published

    Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 04/2016, In: JAMA Psychiatry. 73, 4, p. 369-377 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  77. Published

    Endothelial nitric oxide gene haplotypes and risk of cerebral small-vessel disease

    Hassan, A. E. M., Gormley, K., O'Sullivan, M., Knight, J., Sham, P. C., Vallance, P., Bamford, J. & Markus, H. S., 03/2004, In: Stroke; a journal of cerebral circulation. 35, 3, p. 654-659 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  78. Published

    Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease

    Hamilton, G., Samedi, F., Knight, J., Archer, N., Foy, C., Walter, S., Turic, D., Jehu, L., Moore, P., Hollingworth, P., O'Donovan, M. C., Williams, J., Owen, M. J., Lovestone, S. & Powell, J. F., 19/06/2006, In: Neuroscience Letters. 401, 1-2, p. 77-80 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  79. Published

    Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 6/11/2014, In: American Journal of Human Genetics. 95, 5, p. 535-552 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  80. Published

    Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 04/2018, In: Nature Genetics. 50, 4, p. 538-548 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  81. Published

    Examining the role of common and rare mitochondrial variants in schizophrenia

    Gonçalves, V. F., Giamberardino, S. N., Crowley, J. J., Vawter, M. P., Saxena, R., Bulik, C. M., Yilmaz, Z., Hultman, C. M., Sklar, P., Kennedy, J. L., Sullivan, P. F. & Knight, J., 25/01/2018, In: PLoS ONE. 13, 1, e0191153.

    Research output: Contribution to journalJournal articlepeer-review

  82. Published

    TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease

    Garcia-Barcelo, M., Ganster, R. W., Lui, V. C. H., Leon, T. Y. Y., So, M-T., Lau, A. M. F., Fu, M., Sham, M-H., Knight, J., Zannini, M. S., Sham, P. C. & Tam, P. K. H., 15/01/2005, In: Human Molecular Genetics. 14, 2, p. 191-204 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    Allele-skewed DNA modification in the brain: relevance to a schizophrenia GWAS

    Gagliano, S. A., Ptak, C., Mak, D. Y. F., Shamsi, M., Oh, G., Knight, J., Boutros, P. C. & Petronis, A., 5/05/2016, In: American Journal of Human Genetics. 98, 5, p. 956-962 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  84. Published

    Smoking gun or circumstantial evidence? comparison of statistical learning methods using functional annotations for prioritizing risk variants

    Gagliano, S. A., Ravji, R., Barnes, M. R., Weale, M. E. & Knight, J., 24/08/2015, In: Scientific Reports. 5, 11 p., 13373.

    Research output: Contribution to journalJournal articlepeer-review

  85. Published

    Assessing models for genetic prediction of complex traits: a comparison of visualization and quantitative methods

    Gagliano, S. A., Paterson, A. D., Weale, M. E. & Knight, J., 22/05/2015, In: BMC Genomics. 16, 11 p., 405.

    Research output: Contribution to journalJournal articlepeer-review

  86. Published

    A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization

    Gagliano, S. A., Barnes, M. R., Weale, M. E. & Knight, J., 20/05/2014, In: PLoS ONE. 9, 5, 14 p., e98122.

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    Protein kinase cAMP-dependent regulatory type II beta (PRKAR2B) gene variants in antipsychotic-induced weight gain

    Gagliano, S. A., Tiwari, A. K., Freeman, N., Lieberman, J. A., Meltzer, H. Y., Kennedy, J. L., Knight, J. & Müller, D. J., 07/2014, In: Human Psychopharmacology: Clinical and Experimental. 29, 4, p. 330-335 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  88. Published

    Genomics implicates adaptive and innate immunity in Alzheimer’s and Parkinson’s diseases

    Gagliano, S. A., Pouget, J. G., Hardy, J., Knight, J., Barnes, M. R., Ryten, M. & Weale, M., 12/2016, In: Annals of Clinical and Translational Neurology. 3, 12, p. 924-933 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  89. Published

    Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, 03/2016, In: Nature Reviews Neuroscience. 19, 3, p. 420-431 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  90. Published

    Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality

    Fogh, I., Rijsdijk, F., Andersen, P. M., Sham, P. C., Knight, J., Neale, B., McKenna-Yasek, D., Silani, V., Brown, R. H., Powell, J. F. & Al-Chalabi, A., 08/2007, In: Neurogenetics. 8, 3, p. 235-236 2 p.

    Research output: Contribution to journalLetterpeer-review

  91. Published

    Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene

    Flomen, R., Knight, J., Sham, P., Kerwin, R. & Makoff, A., 1/04/2004, In: Nucleic Acids Research. 32, 7, p. 2113-2122 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  92. Published

    Genetic epistasis regulates amyloid deposition in resilient aging

    Felsky, D., Xu, J., Chibnik, L., Schneider, J., Knight, J., Kennedy, J. L., Bennett, D. A., De Jager, P. L. & Voineskos, A. N., 10/2017, In: Alzheimer's and Dementia. 13, 10, p. 1107-1116 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  93. Published

    Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., Karaman, I., Ng, F. L., Evangelou, M., Witkowska, K., Tzanis, E., Hellwege, J. N., Giri, A., Velez Edwards, D. R., Sun, Y. V., Cho, K., Gaziano, J. M. & 31 others, Wilson, P. W. F., Tsao, P. S., Kovesdy, C. P., Esko, T., Mägi, R., Milani, L., Almgren, P., Boutin, T., Debette, S., Ding, J., Giulianini, F., Holliday, E. G., Jackson, A. U., Li-Gao, R., Lin, W-Y., Luan, J., Mangino, M., Oldmeadow, C., Prins, B. P., Qian, Y., Sargurupremraj, M., Shah, N., Surendran, P., Thériault, S., Verweij, N., Willems, S. M., Zhao, J-H., Amouyel, P., Connell, J., Knight, J. & Million Veteran Program, 17/09/2018, In: Nature Genetics. 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  94. Published

    A Comparison Between Genetics Papers Relating to Immune Disorders and Psychiatric Disorders

    El-Haj, M., Piao, S. S., Rayson, P. E. & Knight, J., 11/09/2017.

    Research output: Contribution to conference - Without ISBN/ISSN Posterpeer-review

  95. Published

    Infrastructure for Semantic Annotation in the Genomics Domain

    El-Haj, M., Rutherford, N., Coole, M., Ezeani, I., Prentice, S., Ide, N., Knight, J., Piao, S., Mariani, J., Rayson, P. & Suderman, K., 11/05/2020, LREC 2020, Twelfth International Conference on Language Resources and Evaluation: LREC'20. Paris: European Language Resources Association (ELRA), p. 6921-6929 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  96. Published

    Transferability Of Ancestry-Specific And Cross-Ancestry CYP2A6 Activity Genetic Risk Scores In African And European Populations

    El-Boraie, A., Chenoweth, M. J., Pouget, J. G., Benowitz, N. L., Fukunaga, K., Mushiroda, T., Kubo, M., Nollen, N. L., Cox, L. S., Lerman, C., Knight, J. & Tyndale, R. F., 31/10/2021, In: Clinical pharmacology and therapeutics. 110, 4, p. 975-985 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  97. Published

    Profiling Medical Journal Articles Using a Gene Ontology Semantic Tagger

    El Haj, M., Rayson, P. E., Piao, S. S. & Knight, J., 11/05/2018, LREC 2018, Eleventh International Conference on Language Resources and Evaluation. Calzolari, N., Choukri, K., Cieri, C., Declerck, T., Goggi, S., Hasida, K., Isahara, H., Maegaard, B., Mariani, J., Mazo, H., Moreno, A., Odijk, J., Piperidis, S. & Tokunaga, T. (eds.). European Language Resources Association (ELRA), p. 4593-4597 5 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  98. Published

    The effect of haplotype-block definitions on inference of haplotype-block structure and htSNPs selection

    Ding, K., Zhou, K., Zhang, J., Knight, J., Zhang, X. & Shen, Y., 01/2005, In: Molecular Biology and Evolution. 22, 1, p. 148-159 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  99. Published

    Dopamine genes and pathological gambling in discordant sib-pairs

    da Silva Lobo, D. S., Vallada, H. P., Knight, J., Martins, S. S., Tavares, H., Gentil, V. & Kennedy, J. L., 12/2007, In: Journal of Gambling Studies. 23, 4, p. 421-433 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  100. Published

    Program report: GENECOUNTING support programs

    Curtis, D., Knight, J. & Sham, P. C., 03/2006, In: Annals of Human Genetics. 70, Pt 2, p. 277-279 3 p.

    Research output: Contribution to journalJournal articlepeer-review

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