Transferability Of Ancestry-Specific And Cross-Ancestry CYP2A6 Activity Genetic Risk Scores In African And European Populations

El-Boraie, A., Chenoweth, M. J., Pouget, J. G., Benowitz, N. L., Fukunaga, K., Mushiroda, T., Kubo, M., Nollen, N. L., Cox, L. S., Lerman, C., Knight, J. & Tyndale, R. F., 31/10/2021, In: Clinical pharmacology and therapeutics. 110, 4, p. 975-985 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., Karaman, I., Ng, F. L., Evangelou, M., Witkowska, K., Tzanis, E., Hellwege, J. N., Giri, A., Velez Edwards, D. R., Sun, Y. V., Cho, K., Gaziano, J. M., & 31 othersWilson, P. W. F., Tsao, P. S., Kovesdy, C. P., Esko, T., Mägi, R., Milani, L., Almgren, P., Boutin, T., Debette, S., Ding, J., Giulianini, F., Holliday, E. G., Jackson, A. U., Li-Gao, R., Lin, W-Y., Luan, J., Mangino, M., Oldmeadow, C., Prins, B. P., Qian, Y., Sargurupremraj, M., Shah, N., Surendran, P., Thériault, S., Verweij, N., Willems, S. M., Zhao, J-H., Amouyel, P., Connell, J., Knight, J. & Million Veteran Program, 17/09/2018, In: Nature Genetics. 20 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic epistasis regulates amyloid deposition in resilient aging

Felsky, D., Xu, J., Chibnik, L., Schneider, J., Knight, J., Kennedy, J. L., Bennett, D. A., De Jager, P. L. & Voineskos, A. N., 10/2017, In: Alzheimer's and Dementia. 13, 10, p. 1107-1116 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene

Flomen, R., Knight, J., Sham, P., Kerwin, R. & Makoff, A., 1/04/2004, In: Nucleic Acids Research. 32, 7, p. 2113-2122 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality

Fogh, I., Rijsdijk, F., Andersen, P. M., Sham, P. C., Knight, J., Neale, B., McKenna-Yasek, D., Silani, V., Brown, R. H., Powell, J. F. & Al-Chalabi, A., 08/2007, In: Neurogenetics. 8, 3, p. 235-236 2 p.

Research output: Contribution to Journal/Magazine › Letter › peer-review

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 03/2016, In: Nature Reviews Neuroscience. 19, 3, p. 420-431 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Allele-skewed DNA modification in the brain: relevance to a schizophrenia GWAS

Gagliano, S. A., Ptak, C., Mak, D. Y. F., Shamsi, M., Oh, G., Knight, J., Boutros, P. C. & Petronis, A., 5/05/2016, In: American Journal of Human Genetics. 98, 5, p. 956-962 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Smoking gun or circumstantial evidence? comparison of statistical learning methods using functional annotations for prioritizing risk variants

Gagliano, S. A., Ravji, R., Barnes, M. R., Weale, M. E. & Knight, J., 24/08/2015, In: Scientific Reports. 5, 11 p., 13373.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Assessing models for genetic prediction of complex traits: a comparison of visualization and quantitative methods

Gagliano, S. A., Paterson, A. D., Weale, M. E. & Knight, J., 22/05/2015, In: BMC Genomics. 16, 11 p., 405.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization

Gagliano, S. A., Barnes, M. R., Weale, M. E. & Knight, J., 20/05/2014, In: PLoS ONE. 9, 5, 14 p., e98122.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Protein kinase cAMP-dependent regulatory type II beta (PRKAR2B) gene variants in antipsychotic-induced weight gain

Gagliano, S. A., Tiwari, A. K., Freeman, N., Lieberman, J. A., Meltzer, H. Y., Kennedy, J. L., Knight, J. & Müller, D. J., 07/2014, In: Human Psychopharmacology: Clinical and Experimental. 29, 4, p. 330-335 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genomics implicates adaptive and innate immunity in Alzheimer’s and Parkinson’s diseases

Gagliano, S. A., Pouget, J. G., Hardy, J., Knight, J., Barnes, M. R., Ryten, M. & Weale, M., 12/2016, In: Annals of Clinical and Translational Neurology. 3, 12, p. 924-933 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease

Garcia-Barcelo, M., Ganster, R. W., Lui, V. C. H., Leon, T. Y. Y., So, M-T., Lau, A. M. F., Fu, M., Sham, M-H., Knight, J., Zannini, M. S., Sham, P. C. & Tam, P. K. H., 15/01/2005, In: Human Molecular Genetics. 14, 2, p. 191-204 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Impact of digital technology in care homes on Emergency Department attendances

Garner, A., Knight, J., Preston, N., Dixon, S., Watchorn, S., Caiado, C., McShane, C., King, G. & Mason, S., 22/11/2022, In: Emergency Medicine Journal. 39, 12, 1 p., A974.

Research output: Contribution to Journal/Magazine › Meeting abstract

The impact of digital technology in care homes on unplanned secondary care usage and associated costs

Garner, A., Lewis, J., Dixon, S., Preston, N., Caiado, C. C. S., Hanratty, B., Jones, M., Knight, J. & Mason, S. M., 29/02/2024, In: Age and Ageing. afae004.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

CYP2A6 associates with respiratory disease risk and younger age of diagnosis: a phenome-wide association Mendelian randomization study

Giratallah, H., Chenoweth, M. J., Pouget, J. G., El-Boraie, A., Alsaafin, A., Lerman, C., Knight, J. & Tyndale, R. F., 15/01/2024, In: Human Molecular Genetics. 33, 2, p. 198-210

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Examining the role of common and rare mitochondrial variants in schizophrenia

Gonçalves, V. F., Giamberardino, S. N., Crowley, J. J., Vawter, M. P., Saxena, R., Bulik, C. M., Yilmaz, Z., Hultman, C. M., Sklar, P., Kennedy, J. L., Sullivan, P. F. & Knight, J., 25/01/2018, In: PLoS ONE. 13, 1, e0191153.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 6/11/2014, In: American Journal of Human Genetics. 95, 5, p. 535-552 18 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 04/2018, In: Nature Genetics. 50, 4, p. 538-548 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease

Hamilton, G., Samedi, F., Knight, J., Archer, N., Foy, C., Walter, S., Turic, D., Jehu, L., Moore, P., Hollingworth, P., O'Donovan, M. C., Williams, J., Owen, M. J., Lovestone, S. & Powell, J. F., 19/06/2006, In: Neuroscience Letters. 401, 1-2, p. 77-80 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Endothelial nitric oxide gene haplotypes and risk of cerebral small-vessel disease

Hassan, A. E. M., Gormley, K., O'Sullivan, M., Knight, J., Sham, P. C., Vallance, P., Bamford, J. & Markus, H. S., 03/2004, In: Stroke; a journal of cerebral circulation. 35, 3, p. 654-659 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 04/2016, In: JAMA Psychiatry. 73, 4, p. 369-377 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review