Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 24/07/2014, In: Nature. 511, 7510, p. 421-427 7 p.

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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, 01/2017, In: Nature Genetics. 49, p. 27-35 9 p.

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Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, 14/06/2018, In: Cell. 173, 7, p. 1705-1715.e16 11 p.

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Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium & Bipolar Disorders Working Group of the Psychiatric Genomics Consortium, 20/06/2017, In: Translational Psychiatry. 7, 6, 9 p., e1155.

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Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

UK NIHR BioResource Rare Diseases Consortium, UK PAH Cohort Study Consortium, US PAH Biobank Consortium, Rhodes, C. J., Batai, K., Bleda, M., Haimel, M., Southgate, L., Germain, M., Pauciulo, M. W., Hadinnapola, C., Aman, J., Girerd, B., Arora, A., Knight, J., Hanscombe, K. B., Karnes, J. H., Kaakinen, M., Gall, H., Ulrich, A., & 33 othersHarbaum, L., Cebola, I., Ferrer, J., Lutz, K., Swietlik, E. M., Ahmad, F., Amouyel, P., Archer, S. L., Argula, R., Austin, E. D., Badesch, D., Bakshi, S., Barnett, C., Benza, R., Bhatt, N., Bogaard, H. J., Burger, C. D., Chakinala, M., Church, C., Coghlan, J. G., Condliffe, R., Corris, P. A., Danesino, C., Debette, S., Elliott, C. G., Elwing, J., Eyries, M., Fortin, T., Franke, A., Frantz, R. P., Frost, A., Garcia, J. G. N. & Ghio, S., 1/03/2019, In: Lancet Respiratory Medicine. 7, 3, p. 227-238 12 p.

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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

CommonMind Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium & iPSYCH-GEMS Schizophrenia Working Group, 1/04/2019, In: Nature Genetics. 51, 4, p. 659-674 16 p.

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GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

M.R.C.Psych & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1/08/2019, In: American Journal of Psychiatry. 176, 8, p. 651-660 10 p.

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The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium 2, 1/08/2019, In: Neuropsychopharmacology. 44, 9, p. 1562-1569 8 p.

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Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

Wellcome Trust Case Control Consortium 2 & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1/04/2019, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 180, 3, p. 223-231 9 p.

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The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia

GROUP Investigators & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1/03/2020, In: Schizophrenia Bulletin. 46, 2, p. 336-344 9 p.

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A polygenic resilience score moderates the genetic risk for schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 6/09/2019, In: Molecular Psychiatry. 2019, 16 p.

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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium. Electronic address: plee0@mgh.harvard.edu, 12/12/2019, In: Cell. 179, 7, p. 1469-1482.e11 14 p.

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Comparative genetic architectures of schizophrenia in East Asian and European populations

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 31/12/2019, In: Nature Genetics. 51, 12, p. 1670-1678 9 p.

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Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

ADHD Working Group of the Psychiatric Genomics Consortium, 18/12/2019, In: Nature Communications. 10, 1, 12 p., 5765.

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Complement genes contribute sex-biased vulnerability in diverse disorders

Schizophrenia Working Group of the Psychiatric Genomics Consortium 2, 11/05/2020, (E-pub ahead of print) In: Nature. 28 p.

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Attention-Deficit Hyperactivity Disorder in the post-genomic era

Asherson, P., Knight, J. & IMAGE Consortium, 07/2004, In: European Child and Adolescent Psychiatry. 13 , Suppl 1, p. I50-70 21 p.

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Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

Beall, C. M., Cavalleri, G. L., Deng, L., Elston, R. C., Gao, Y., Knight, J., Li, C., Li, J. C., Liang, Y., McCormack, M., Montgomery, H. E., Pan, H., Robbins, P. A., Shianna, K. V., Tam, S. C., Tsering, N., Veeramah, K. R., Wang, W., Wangdui, P., Weale, M. E., & 9 othersXu, Y., Xu, Z., Yang, L., Zaman, M. J., Zeng, C., Zhang, L., Zhang, X., Zhaxi, P. & Zheng, Y. T., 22/06/2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11459-11464 6 p.

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Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 03/2016, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 171B, 2, p. 276-89 14 p.

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Routinely collected patient data in neurology research: a systematic mapping review

Biggin, F., Emsley, H. & Knight, J., 27/11/2020, In: BMC Neurology. 20, 9 p., 431.

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Variation in waiting times by diagnostic category: an observational study of 1,951 referrals to a neurology outpatient clinic

Biggin, F., Howcroft, T., Davies, Q., Knight, J. & Emsley, H., 31/05/2021, In: BMJ Neurology Open. 3, 1, 8 p., 000133.

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Outpatient neurology diagnostic coding: a proposed scheme for standardised implementation

Biggin, F., Knight, J., Dayanandan, R., Marson, A., Wilson, M., Nitkunan, A., Rog, D., Kipps, C., Mummery, C., Williams, A. & Emsley, H. C. A., 1/08/2023, In: Practical Neurology. 23, 4, p. 317-322 6 p.

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Discovering patterns in outpatient neurology appointments using state sequence analysis

Biggin, F., Ashcroft, Q., Howcroft, T., Knight, J. & Emsley, H., 6/11/2023, In: BMC Health Services Research. 23, 1, 1208.

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A genome-wide significant linkage for severe depression on chromosome 3: the depression network study

Breen, G., Webb, B. T., Butler, A. W., van den Oord, E. J. C. G., Tozzi, F., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., Mors, O., Owen, M. J., Cohen-Woods, S., Perry, J., Galwey, N. W., Upmanyu, R., Craig, I., Lewis, C. M., Ng, M., Brewster, S., & 8 othersPreisig, M., Rietschel, M., Jones, L., Knight, J., Rice, J., Muglia, P., Farmer, A. E. & McGuffin, P., 08/2011, In: American Journal of Psychiatry. 168, 8, p. 840-847 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

Brookes, K., Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., Anney, R., Franke, B., Gill, M., Ebstein, R., Buitelaar, J., Sham, P., Campbell, D., Knight, J., Andreou, P., Altink, M., Arnold, R., Boer, F., Buschgens, C., Butler, L., & 42 othersChristiansen, H., Feldman, L., Fleischman, K., Fliers, E., Howe-Forbes, R., Goldfarb, A., Heise, A., Gabriëls, I., Korn-Lubetzki, I., Johansson, L., Marco, R., Medad, S., Minderaa, R., Mulas, F., Müller, U., Mulligan, A., Rabin, K., Rommelse, N., Sethna, V., Sorohan, J., Uebel, H., Psychogiou, L., Weeks, A., Barrett, R., Craig, I., Banaschewski, T., Sonuga-Barke, E., Eisenberg, J., Kuntsi, J., Manor, I., McGuffin, P., Miranda, A., Oades, R. D., Plomin, R., Roeyers, H., Rothenberger, A., Sergeant, J., Steinhausen, H-C., Taylor, E., Thompson, M., Faraone, S. V. & Asherson, P., 10/2006, In: Molecular Psychiatry. 11, 10, p. 934-953 20 p.

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A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy

Brookes, K-J., Mill, J., Guindalini, C., Curran, S., Xu, X., Knight, J., Chen, C-K., Huang, Y-S., Sethna, V., Taylor, E., Chen, W., Breen, G. & Asherson, P., 01/2006, In: Archives of General Psychiatry. 63, 1, p. 74-81 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review