Mammographic dysplasia as entry criterion for breast cancer prevention trials

Berridge, D., Whitehead, J. & Cuzick, J., 18/05/1991, In: The Lancet. 337, 8751, p. 1225 1 p.

Research output: Contribution to Journal/Magazine › Letter › peer-review

Analysis of failure time data with ordinal categories of response

Berridge, D. & Whitehead, J., 11/1991, In: Statistics in Medicine. 10, 11, p. 1703-1710 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Easy-to-implement Bayesian methods for dose-escalation studies in healthy volunteers.

Whitehead, J., Patterson, S., Webber, D. & Zhou, Y., 03/2001, In: Biostatistics. 2, 1, p. 47-61 15 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Incorporating data received after a sequential trial has stopped into the final analysis: implementation and comparison of methods.

Whitehead, J., Bollard, K., Matsushita, T., Sooriyarachchi, M. R. & Whitehead, A., 09/2003, In: Biometrics. 59, 3, p. 701-709 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The sequential analysis of repeated binary responses: a score test for the case of three time points.

Sooriyarachchi, M. R., Whitehead, J., Whitehead, A. & Bolland, K., 15/07/2006, In: Statistics in Medicine. 25, 13, p. 2196-2214 19 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Sequential genome-wide association studies for monitoring adverse events in clinical evaluation of new drugs.

Whitehead, J., Kelly, P. J., Stallard, N., Zhou, Y. & Bowman, C., 30/09/2006, In: Statistics in Medicine. 25, 18, p. 3081-3092 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Bayesian approach for dose-escalation in a phase I clinical trial incorporating pharmacodynamic endpoints .

Whitehead, J., Hampson, L., Zhou, Y., Ledent, E. & Pereira, A., 11/2007, In: Journal of Biopharmaceutical Statistics. 17, 6, p. 1117-1129 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Implementation of a Bayesian design in a dose-escalation study of an experimental agent in healthy volunteers.

Whitehead, J., Korhonen, P., Mustonen, M. & Zhou, Y., 03/2008, In: Biometrics. 64, 1, p. 299-308 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Incorporating intermediate binary responses into interim analyses of clinical trials : a comparison of four methods.

Whitehead, A., Sooriyarachchi, M. R., Whitehead, J. & Bolland, K., 10/05/2008, In: Statistics in Medicine. 27, 10, p. 1646-1666 21 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Sequentially testing for a gene-drug interaction in a genomewide analysis.

Kelly, P., Zhou, Y., Whitehead, J., Stallard, N. & Bowman, C., 20/05/2008, In: Statistics in Medicine. 27, 11, p. 2022-2034 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bayesian sample size for exploratory clinical trials incorporating historical data.

Whitehead, J., Valdés-Márquez, E., Johnson, P. & Graham, G., 06/2008, In: Statistics in Medicine. 27, 13, p. 2307-2327 21 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A safety monitoring procesure for a clinical drug development programme, with application to the accessment of a novel COX-2 inhibitor.

Bolland, K., Whitehead, J. & Oldham, M., 07/2008, In: Journal of Biopharmaceutical Statistics. 18, 4, p. 737-749 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Estimation following selection of the largest of two normal means. Journal of Statistical Planning and Inference 138, 1629-1638.

Stallard, N., Todd, S. & Whitehead, J., 1/07/2008, In: Journal of Statistical Planning and Inference. 138, 6, p. 1629-1638 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Fitting models for the joint action of two drugs using SAS(R).

Whitehead, A., Whitehead, J., Todd, S., Zhou, Y. & Smith, M. K., 10/2008, In: Pharmaceutical Statistics. 7, 4, p. 272-284 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint.

Whitehead, J. & Jaki, T., 28/02/2009, In: Statistics in Medicine. 28, 5, p. 828-847 20 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A simple two-stage design for quantitative responses with appliction to a study in diabectic neuropathic pain.

Whitehead, J., Valdés-Márquez, E. & Lissmats, A., 04/2009, In: Pharmaceutical Statistics. 8, 2, p. 125-135 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Evaluation of a sequential global test of improved recovery following stroke as applied to the ICTUS trial of citicoline.

Bolland, K., Whitehead, J., Cobo, E. & Secades, J. J., 04/2009, In: Pharmaceutical Statistics. 8, 2, p. 136-149 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Using historical lesion volume data in the design of a new phase II clinical trial in acute stroke.

Whitehead, J., Bolland, K., Valdés-Márquez, E., Lihic, A., Ali, M. & Lees, K., 04/2009, In: Stroke. 40, 4, p. 1347-1352 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme.

Whitehead, J., Kelly, P., Zhou, Y., Stallard, N., Thygesen, H. & Bowman, C., 10/2009, In: Pharmaceutical Statistics. 8, 4, p. 287-300 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A combined score test for binary and ordinal endpoints from clinical trials.

Whitehead, J., Branson, M. & Todd, S., 28/02/2010, In: Statistics in Medicine. 29, 5, p. 521-532 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Bayesian dose-escalation procedure for phase I clinical trials based only on the assumption of monotonicity.

Whitehead, J., Thygesen, H. & Whitehead, A., 30/07/2010, In: Statistics in Medicine. 29, 17, p. 1808-1824 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bayesian procedures for phase I/II clinical trials investigating the safety and efficacy of drug combinations

Whitehead, J., Thygesen, H. & Whitehead, A., 20/07/2011, In: Statistics in Medicine. 30, 16, p. 1952-1970 19 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A generalized Dunnett Test for Multi-arm Multi-stage Clinical Studies with Treatment Selection

Magirr, D., Jaki, T. & Whitehead, J., 06/2012, In: Biometrika. 99, 2, p. 494-501 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A novel phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer

Whitehead, J., Thygesen, H., Jaki, T., Davis, S., Halford, S., Turner, H., Cook, N. & Jodrell, D., 15/08/2012, In: Statistics in Medicine. 31, 18, p. 1931-1943 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A bivariate Bayesian dose-finding procedure applied to a seamless phase I/II trial in rheumatoid arthritis

Thygesen, H., Dragalin, V., Whitehead, A. & Whitehead, J., 11/2012, In: Pharmaceutical Statistics. 11, 6, p. 476-484 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Designing exploratory cancer trials using change in tumour size as primary endpoint

Jaki, T., Andre, V., Su, T-L. & Whitehead, J., 10/07/2013, In: Statistics in Medicine. 32, 15, p. 2544-2554 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bayesian methods for the design and interpretation of clinical trials in very rare diseases

Hampson, L., Whitehead, J., Eleftheriou, D. & Brogan, P., 30/10/2014, In: Statistics in Medicine. 33, 24, p. 4186-4201 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Elicitation of expert prior opinion: application to the MYPAN trial in childhood polyarteritis nodosa

Beresford, M. W., Bracaglia, C., Caldas, A., Cimaz, R., Dehoorne, J., Dolezalova, P., Friswell, M., Jelusic, M., Marks, S. D., Martin, N., McMahon, A-M., Peitz, J., van Royen-Kirkhof, A., Soylemezoglu, O., Brogan, P. & MYPAN Vasculitis Expert Group, 30/03/2015, In: PLoS ONE. 10, 3, 14 p., e0120981.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bayesian sample sizes for exploratory clinical trials comparing multiple experimental treatments with a control

Whitehead, J., Cleary, F. & Turner, A., 30/05/2015, In: Statistics in Medicine. 34, 12, p. 2048-2061 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Partial stochastic dominance for the multivariate Gaussian distribution

Turner, A. & Whitehead, J., 08/2015, In: Statistics and Probability Letters. 103, p. 80-85 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of Telmisartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on combination antiretroviral therapy

Pushpakom, S. P., Taylor, C., Kolamunnage-Dona, R., Spowart, C., Vora, J., Garcıa-Finana, M., Kemp, G. J., Whitehead, J., Jaki, T., Khoo, S., Williamson, P. & Pirmohamed, M., 15/10/2015, In: BMJ Open. 5, 10, 13 p., e009566.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function

Yeung, W. Y., Whitehead, J. R., Reigner, B., Beyer, U., Diack, C. & Jaki, T. F., 11/2015, In: Pharmaceutical Statistics. 14, 6, p. 479-487 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol

Arabi, Y., Balkhy, H., Hajeer, A. H., Bouchama, A., Hayden, F. G., Al-Omari, A., Al-Hameed, F. M., Taha, Y., Shindo, N., Whitehead, J. R., Merson, L., AlJohani, S., Al-Khairy, K., Carson, G., Luke, T. C., Hensley, L., Al-Dawood, A., Al-Qahtani, S., Modjarrad, K., Sadat, M., & 3 othersRohde, G., Leport, C. & Fowler, R., 19/11/2015, In: SpringerPlus. 2015, 4, 8 p., 709.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Trial design for evaluating novel treatments during an outbreak of an infectious disease

Whitehead, J. R., Olliaro, P., Lang, T. & Horby, P. W., 02/2016, In: Clinical Trials. 13, 1, p. 31-38 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Experimental treatment of Ebola virus disease with TKM-130803: a single-arm phase 2 clinical trial

RAPIDE-TKM trial team, 19/04/2016, In: PLoS Medicine. 13, 4, 19 p., e1001997.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A comparison of the barely Bayesian design with the triangular test for clinical trials in infectious diseases

Whitehead, J. R., 08/2016, In: Clinical Trials. 13, 4, p. 451-453 3 p.

Research output: Contribution to Journal/Magazine › Letter › peer-review

Experimental treatment of Ebola virus disease with Brincidofovir

Rapide-BCV trial team, 9/09/2016, In: PLoS ONE. 11, 9, 10 p., e162199.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Estimation of treatment effects following a sequential trial of multiple treatments

Whitehead, J., Desai, Y. & Jaki, T., 20/05/2020, In: Statistics in Medicine. 39, 11, p. 1593-1609 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Efficient Adaptive Designs for Clinical Trials of Interventions for COVID-19

Stallard, N., Hampson, L., Benda, N., Brannath, W., Burnett, T., Friede, T., Kimani, P. K., Koenig, F., Krisam, J., Mozgunov, P., Posch, M., Wason, J., Wassmer, G., Whitehead, J., Williamson, S. F., Zohar, S. & Jaki, T., 1/10/2020, In: Statistics in Biopharmaceutical Research. 12, 4, p. 483-497 15 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

On the Unreliability of Multiple Systems Estimation for Estimating the Number of Potential Victims of Modern Slavery in the UK

Whitehead, J., Jackson, J., Balch, A. & Francis, B., 2/01/2021, In: Journal of Human Trafficking. 7, 1, p. 1-13 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial

Brogan, P. A., Arch, B., Hickey, H., Anton, J., Iglesias, E., Baildam, E., Mahmood, K., Cleary, G., Moraitis, E., Papadopoulou, C., Beresford, M. W., Riley, P., Demir, S., Ozen, S., Culeddu, G., Hughes, D. A., Dolezalova, P., Hampson, L., Whitehead, J., Jayne, D., & 3 othersRuperto, N., Tudur-Smith, C. & Eleftheriou, D., 30/09/2021, In: Arthritis and Rheumatology. 73, 9, p. 1673-1682 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Whitehead et al. Response to “Misunderstandings of Multiple Systems Estimation.”

Whitehead, J., Jackson, J., Balch, A. & Francis, B., 31/10/2022, In: Journal of Human Trafficking. 8, 4, p. 469-473 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Discussion on “The central role of the identifying assumption in population size estimation” by Serge Aleshin-Guendel, Mauricio Sadinle, and Jon Wakefield

Whitehead, J., 31/03/2024, In: Biometrics. 80, 1, ujad031.

Research output: Contribution to Journal/Magazine › Journal article › peer-review