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Research

Dr Karen Wright

Senior Lecturer in Biomedicine

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  1. 2008
  2. Published

    Cannabinoid CB2 receptors in the gastrointestinal tract : a regulatory system in states of inflammation.

    Wright, K. L., Duncan, M. & Sharkey, K. A., 01/2008, In: British Journal of Pharmacology. 153, 2, p. 263-270 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2007
  4. Published

    Temporal variation in CB2R levels following T lymphocyte activation : evidence that cannabinoids modulate CXCL12-induced chemotaxis.

    Coopman, K., Smith, L. D., Wright, K. L. & Ward, S. G., 03/2007, In: International Immunopharmacology. 7, 3, p. 360-371 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. 2006
  6. Published

    Peripheral cannabinoid receptor, CB2, regulates bone mass.

    Ofek, O., Karsak, M., Leclerc, N., Fogel, M., Frenkel, B., Wright, K., Tam, J., Attar-Namdar, M., Kram, V., Shohami, E., Mechoulam, R., Zimmer, A. & Bab, I., 17/01/2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 3, p. 696-701 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. 2005
  8. Published

    The Chemokines CXCL9, CXCL10, and CXCL11 Differentially Stimulate Gαi-Independent Signaling and Actin Responses in Human Intestinal Myofibroblasts.

    Kouroumalis, A., Nibbs, R. J., Aptel, H., Wright, K. L., Kolios, G. & Ward, S. G., 15/10/2005, In: Journal of Immunology. 175, 8, p. 5403-5411 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPARγ agonists: evidence for disparate functional effects which are independent of NF-κB and PPARγ

    Patel, K. M., Wright, K. L., Whittaker, P., Chakravarty, P., Watson, M. L. & Ward, S. G., 09/2005, In: Cellular Signalling. 17, 9, p. 1098-1110 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Differential Expression of Cannabinoid Receptors in the Human Colon : Cannabinoids Promote Epithelial Wound Healing.

    Wright, K., Rooney, N., Feeney, M., Tate, J., Robertson, D., Welham, M. & Ward, S., 08/2005, In: Gastroenterology. 129, 2, p. 437-453 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. 2004
  12. Published

    Differential regulation of prostaglandin E biosynthesis by interferon-γ in colonic epithelial cells.

    Wright, K. L., Weaver, S. A., Patel, K., Coopman, K., Feeney, M., Kolios, G., Robertson, D. A. F. & Ward, S. G., 04/2004, In: British Journal of Pharmacology. 141, 7, p. 1091-1097 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. 2003
  14. Published

    Optimal Chemotactic Responses of Leukemic T Cells to Stromal Cell-Derived Factor-1 Requires the Activation of Both Class IA and IB Phosphoinositide 3-Kinases.

    Curnock, A. P., Sotsios, Y., Wright, K. L. & Ward, S. G., 15/04/2003, In: Journal of Immunology. 170, 8, p. 4021-4030 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. 2002
  16. Published

    Evidence That SHIP-1 Contributes to Phosphatidylinositol 3,4,5-Trisphosphate Metabolism in T Lymphocytes and Can Regulate Novel Phosphoinositide 3-Kinase Effectors.

    Freeburn, R. W., Wright, K. L., Burgess, S. J., Astoul, E., Cantrell, D. A. & Ward, S. G., 15/11/2002, In: Journal of Immunology. 169, 10, p. 5441-5450 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. 2001
  18. Published

    Regulatory role of phosphatidylinositol 3-kinase on TNF-α-induced cyclooxygenase 2 expression in colonic epithelial cells.

    Weaver, S. A., Russo, M. P., Wright, K. L., Kolios, G., Jobin, C., Robertson, D. A. F. & Ward, S. G., 04/2001, In: Gastroenterology. 120, 5, p. 1117-1127 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. 2000
  20. Published

    Interactions between Phosphatidylinositol 3-Kinase and Nitric Oxide: Explaining the Paradox

    Wright, K. L. & Ward, S. G., 09/2000, In: Molecular Cell Biology Research Communications. 4, 3, p. 137-143 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Interleukin-13 inhibits nitric oxide production in human colonic mucosa.

    Kolios, G., Wright, K. L., Linehan, J. D., Robertson, D. A. F. & Westick, J., 2000, In: Hepato-Gastroenterology. 47, p. 714-717 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. 1999
  23. Published

    Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation : evidence for an IL-13-driven PI3-kinase-dependent survival mechanism.

    Wright, K., Kolios, G., Westwick, J. & Ward, S. G., 11/06/1999, In: Journal of Biological Chemistry. 274, 24, p. 17193-17201 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    C-X-C and C-C chemokine expression and secretion by the human colonic epithelial cell line, HT-29 : differential effect of T lymphocyte-derived cytokines.

    Kolios, G., Wright, K. L., Jordan, N. J., Leithead, J. B., Robertson, D. A. F. & Westwick, J., 02/1999, In: European Journal of Immunology. 29, 2, p. 530-536 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. 1997
  26. Published

    Activation of phosphatidylinositol 3-kinase by interleukin-13 - An inhibitory signal for inducible nitric-oxide synthase expression in the epithelial, cell line HT-29.

    Wright, K., Ward, S. G., Kolios, G. & Westwick, J., 9/05/1997, In: Journal of Biological Chemistry. 272, p. 12626-12633 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  27. Published

    Regulation of inflammatory mediator production in human colonic epithelial cells.

    Kolios, G., Wright, K. L., Jordan, N. J., Leithead, J. B., Murphy, C. T., Robertson, D. A. F. & Westwick, J., 1997, In: Hellenic Journal of Gastroenterology. 10, 2, p. 135-147 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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