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Dr Lisa Hampson

Formerly at Lancaster University

  1. Published

    A Bayesian approach for dose-escalation in a phase I clinical trial incorporating pharmacodynamic endpoints .

    Whitehead, J., Hampson, L., Zhou, Y., Ledent, E. & Pereira, A., 11/2007, In: Journal of Biopharmaceutical Statistics. 17, 6, p. 1117-1129 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    A Bayesian decision-theoretic approach to incorporate preclinical information into phase I oncology trials

    Zheng, H. & Hampson, L. V., 1/10/2020, In: Biometrical Journal. 62, 6, p. 1408-1427 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    A proposal for a new PhD level curriculum on quantitative methods for drug development

    Jaki, T. F., Gordon, A., Forster, P. S., Bijnens, L., Bornkamp, B., Brannath, W., Fontana, R., Gasparini, M., Hampson, L. V., Jacobs, T., Jones, B., Paoletti, X., Posch, M., Titman, A. C., Vonk, R. & Koenig, F., 09/2018, In: Pharmaceutical Statistics. 17, 5, p. 593-606 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    A quantitative framework to inform extrapolation decisions in children

    Wadsworth, I., Hampson, L. V., Jaki, T., Sills, G. J., Marson, A. G. & Appleton, R., 1/02/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 2, p. 515-534 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. E-pub ahead of print

    A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials

    Zheng, H., Hampson, L. V. & Wandel, S., 16/01/2019, (E-pub ahead of print) In: Statistical Methods in Medical Research. 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children

    Hampson, L. V., Fisch, R., Van, L. M. & Jaki, T. F., 10/02/2017, In: Statistics in Medicine. 36, 3, p. 426-441 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Bayesian methods for the design and interpretation of clinical trials in very rare diseases

    Hampson, L., Whitehead, J., Eleftheriou, D. & Brogan, P., 30/10/2014, In: Statistics in Medicine. 33, 24, p. 4186-4201 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Bayesian survival analysis in clinical trials: what methods are used in practice?

    Brard, C., Le Teuff, G., Le Deley, M-C. & Hampson, L. V., 1/02/2017, In: Clinical Trials. 14, 1, p. 78-87 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Bridging across patient subgroups in phase I oncology trials that incorporate animal data

    Zheng, H., Hampson, L. V. & Jaki, T., 1/04/2021, In: Statistical Methods in Medical Research. 30, 4, p. 1057-1071 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Bridging the gap: a review of dose investigations in paediatric investigation plans

    Hampson, L., Herold, R., Posch, M., Saperia, J. & Whitehead, A., 10/2014, In: British Journal of Clinical Pharmacology. 78, 4, p. 898-907 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    C Code to design error spending tests for delayed responses

    Hampson, L. & Jennison, C., 3/09/2012

    Research output: Exhibits, objects and web-based outputsSoftware

  12. Published

    Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - The development of the DELTA2 guidance

    Sones, W., Julious, S. A., Rothwell, J. C., Ramsay, C. R., Hampson, L. V., Emsley, R., Walters, S. J., Hewitt, C., Bland, M., Fergusson, D. A., Berlin, J. A., Altman, D., Vale, L. D. & Cook, J. A., 10/10/2018, In: Trials. 19, 1, 11 p., 542.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Clinical drug development in epilepsy revisited: a proposal for a new paradigm streamlined using extrapolation

    Wadsworth, I., Jaki, T. F., Sills, G. J., Appleton, R., Cross, J. H., Marson, A. G., Martland, T., McLellan, A., Smith, P. E. M., Pellock, J. M. & Hampson, L. V., 11/2016, In: CNS Drugs. 30, 11, p. 1011-1017 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Cost-utility analysis conducted alongside randomized controlled trials: Are economic end points considered in sample size calculations and does it matter?

    Hollingworth, W., McKell-Redwood, D., Hampson, L. & Metcalfe, C., 02/2013, In: Clinical Trials. 10, 1, p. 43-53 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    DELTA 2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

    Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C. F., MacLennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., & 1 othersVale, L. D., 5/11/2018, In: BMJ. 363, 7 p., 363.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial Suzie Cro

    Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C. F., Maclennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., & 1 othersVale, L. D., 5/11/2018, In: Trials. 19, 1, 8 p., 606.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Designing and evaluating dose-escalation studies made easy: The MoDEsT web app

    Pallmann, P., Wan, F., Mander, A. P., Wheeler, G. M., Yap, C., Clive, S., Hampson, L. V. & Jaki, T., 1/04/2020, In: Clinical Trials. 17, 2, p. 147-156 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection

    Jaki, T. & Hampson, L., 20/02/2016, In: Statistics in Medicine. 35, 4, p. 522-533 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Elicitation of expert prior opinion: application to the MYPAN trial in childhood polyarteritis nodosa

    Beresford, M. W., Bracaglia, C., Caldas, A., Cimaz, R., Dehoorne, J., Dolezalova, P., Friswell, M., Jelusic, M., Marks, S. D., Martin, N., McMahon, A-M., Peitz, J., van Royen-Kirkhof, A., Soylemezoglu, O., Brogan, P. & MYPAN Vasculitis Expert Group, 30/03/2015, In: PLoS ONE. 10, 3, 14 p., e0120981.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Exercise and self-management for people with chronic knee, hip or lower back pain: a cluster randomised controlled trial of clinical and cost-effectiveness. Study protocol

    Walsh, N., Cramp, F., Palmer, S., Pollock, J., Hampson, L., Gooberman-Hill, R., Green, C., Jones, L., Phillips, S., Johnson, L. & Hurley, M., 12/2013, In: Physiotherapy. 99, 4, p. 352-357 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Exposure–response modelling approaches for determining optimal dosing rules in children

    Wadsworth, I., Hampson, L. V., Bornkamp, B. & Jaki, T., 1/09/2020, In: Statistical Methods in Medical Research. 29, 9, p. 2583-2602 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Extrapolation of efficacy and other data to support the development of new medicines for children: a systematic review of methods

    Wadsworth, I., Hampson, L. V. & Jaki, T. F., 1/02/2018, In: Statistical Methods in Medical Research. 27, 2, p. 398-413 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Group sequential tests for delayed responses

    Hampson, L. & Jennison, C., 01/2013, In: Journal of the Royal Statistical Society: Series B (Statistical Methodology). 75, 1, p. 3-54 52 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Incorporating prognostic factors into causal estimators: a comparison of methods for RCTs with a time to event outcome

    Hampson, L. & Metcalfe, C., 20/11/2012, In: Statistics in Medicine. 31, 26, p. 3073-3088 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial

    Brogan, P. A., Arch, B., Hickey, H., Anton, J., Iglesias, E., Baildam, E., Mahmood, K., Cleary, G., Moraitis, E., Papadopoulou, C., Beresford, M. W., Riley, P., Demir, S., Ozen, S., Culeddu, G., Hughes, D. A., Dolezalova, P., Hampson, L., Whitehead, J., Jayne, D., & 3 othersRuperto, N., Tudur-Smith, C. & Eleftheriou, D., 30/09/2021, In: Arthritis and Rheumatology. 73, 9, p. 1673-1682 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  26. Published

    Optimising the data combination rule for seamless phase II/III clinical trials

    Hampson, L. & Jennison, C., 01/2015, In: Statistics in Medicine. 34, 1, p. 39-58 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  27. Published

    Planification d’un essai randomisé bayésien avec critère de survie: spécification du modèle incorporant les données historiques

    Brard, C., Hampson, L. V., Le Deley, M-C. & Le Teuff, G., 05/2016, In: Revue d'Épidémiologie et de Santé Publique. 64, Suppl. 3

    Research output: Contribution to Journal/MagazineMeeting abstractpeer-review

  28. Published
  29. Published

    Response to comments on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharm Stat 17(5):593-606, Sep/Oct 2018., DOI https://doi.org/10.1002/pst.1873

    Jaki, T., Gordon, A., Forster, P., Bijnens, L., Bornkamp, B., Brannath, W., Fontana, R., Gasparini, M., Hampson, L. V., Jacobs, T., Jones, B., Paoletti, X., Posch, M., Titman, A., Vonk, R. & Koenig, F., 1/05/2019, In: Pharmaceutical Statistics. 18, 3, p. 284-286 3 p.

    Research output: Contribution to Journal/MagazineLetterpeer-review

  30. Published

    Study to evaluate the optimal dose of remifentanil required to ensure apnea during magnetic resonance imaging of the heart under general anesthesia

    Arnold, P., Sanaulla, S., Hampson, L. V., Davis, A., Tan, J., Cowen, R., Kaleem, M., Williams, A., Wadsworth, I. & Jaki, T., 31/05/2021, In: Paediatric Anesthesia. 31, 5, p. 548-556 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  31. Published

    'Threshold crossing': a useful way to establish the counterfactual in clinical trials?

    Eichler, H-G., Bloechl-Daum, B., Bauer, P., Bretz, F., Brown, J., Hampson, L. V., Honig, P., Krams, M., Leufkens, H., Lim, R., Lumpkin, M., Murphy, M., Pignatti, F., Posch, M., Schneeweiss, S., Trusheim, M. & Koenig, F., 12/2016, In: Clinical Pharmacology & Therapeutics. 100, p. 699-712 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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