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Research

Professor Mick Urbaniak

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  1. 2008
  2. Published

    Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues

    Urbaniak, M. D., Yashunsky, D. V., Crossman, A., Nikolaev, A. V. & Ferguson, M. A. J., 17/10/2008, In: ACS Chemical Biology. 3, 10, p. 625-634 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2009
  4. Published

    Casein kinase 1 isoform 2 is essential for bloodstream form Trypanosoma brucei

    Urbaniak, M. D., 08/2009, In: Molecular and Biochemical Parasitology. 166, 2, p. 183-185 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Chapter 3 The GlcNAc-PI de-N-acetylase. Structure, function, and activity

    Urbaniak, M. D. & Ferguson, M. A. J., 1/12/2009, In: Enzymes. 26, C, p. 49-64 16 p.

    Research output: Contribution to Journal/Magazine › Review article › peer-review

  6. 2010
  7. Published

    A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology

    Durrant, J. D., Amaro, R. E., Xie, L., Urbaniak, M. D., Ferguson, M. A. J., Haapalainen, A., Chen, Z., Di Guilmi, A. M., Wunder, F., Bourne, P. E. & McCammon, J. A., 22/01/2010, In: PLoS Computational Biology. 6, 1, 8 p., e1000648.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors: toward the development of novel therapies for African sleeping sickness

    Durrant, J. D., Urbaniak, M. D., Ferguson, M. A. J. & McCammon, J. A., 8/07/2010, In: Journal of Medicinal Chemistry. 53, 13, p. 5025-5032 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2011
  10. Published

    Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei

    Abdelwahab, N. Z., Urbaniak, M. D., Ferguson, M. A. J. & Crossman, A. T., 1/05/2011, In: Carbohydrate Research. 346, 6, p. 708-714 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. 2012
  12. Published

    Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

    Abdelwahab, N. Z., Crossman, A. T., Sullivan, L., Ferguson, M. A. J. & Urbaniak, M., 03/2012, In: Chemical Biology and Drug Design. 79, 3, p. 270-278 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Comparative SILAC proteomic analysis of Trypanosoma brucei bloodstream and procyclic lifecycle stages

    Urbaniak, M., Guther, M. L. S. & Ferguson, M. A. J., 4/05/2012, In: PLoS ONE. 7, 5, 8 p., e36619.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei

    Urbaniak, M. D., Mathieson, T., Bantscheff, M., Eberhard, D., Grimaldi, R., Miranda-Saavedra, D., Wyatt, P., Ferguson, M. A. J., Frearson, J. & Drewes, G., 16/11/2012, In: ACS Chemical Biology. 7, 11, p. 1858-1865 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. 2013
  16. Published

    Global quantitative SILAC phosphoproteomics reveals differential phosphorylation is widespread between the procyclic and bloodstream form lifecycle stages of Trypanosoma brucei

    Urbaniak, M., Ferguson, M. A. J. & Martin, D. M. A., 14/03/2013, In: Journal of Proteome Research. 12, p. 2233-2244 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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