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Research

Professor Mick Urbaniak

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  1. 2014
  2. Published

    High-confidence glycosome proteome for procyclic form Trypanosoma brucei by epitope-tag organelle enrichment and SILAC proteomics

    Güther, M. L. S., Urbaniak, M. D., Tavendale, A., Prescott, A. & Ferguson, M. A. J., 2014, In: Journal of Proteome Research. 13, 6, p. 2796-2806 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues

    Capes, A. S., Crossman, A., Urbaniak, M. D., Gilbert, S. H., Ferguson, M. A. J. & Gilbert, I. H., 2014, In: Organic and Biomolecular Chemistry . 2014, 12, p. 1919-1934 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Trypanosomatid Phosphoproteomics

    Urbaniak, M., 2014, Protein phosphorylation in parasites: novel targets for antiparasitic intervention. Doerig, C., Spath, G. & Wiese, M. (eds.). Chichester: Wiley Blackwell, p. 63-78 16 p. (Drug Discovery in Infectious Diseases).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  5. 2013
  6. Published

    A novel allosteric inhibitor of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei.

    Urbaniak, M., Collie, I. T., Fang, W., Aristotelous, T., Eskilsson, S., Raimi, O. G., Harrison, J., Hopkins Navratilova, I., Frearson, J. A., van Aalten, D. M. F. & Ferguson, M. A. J., 20/09/2013, In: ACS Chemical Biology. 8, 9, p. 1981-1987 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as a potential antifungal target

    Fang, W., Du, T., Raimi, O. G., Hurtado-Guerrero, R., Urbaniak, M., Ibrahim, A. F. M., Ferguson, M. A. J. & van Aalten, D. M. F., 08/2013, In: Molecular Microbiology. 89, 3, p. 479-493 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Global quantitative SILAC phosphoproteomics reveals differential phosphorylation is widespread between the procyclic and bloodstream form lifecycle stages of Trypanosoma brucei

    Urbaniak, M., Ferguson, M. A. J. & Martin, D. M. A., 14/03/2013, In: Journal of Proteome Research. 12, p. 2233-2244 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2012
  10. Published

    Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei

    Urbaniak, M. D., Mathieson, T., Bantscheff, M., Eberhard, D., Grimaldi, R., Miranda-Saavedra, D., Wyatt, P., Ferguson, M. A. J., Frearson, J. & Drewes, G., 16/11/2012, In: ACS Chemical Biology. 7, 11, p. 1858-1865 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Comparative SILAC proteomic analysis of Trypanosoma brucei bloodstream and procyclic lifecycle stages

    Urbaniak, M., Guther, M. L. S. & Ferguson, M. A. J., 4/05/2012, In: PLoS ONE. 7, 5, 8 p., e36619.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

    Abdelwahab, N. Z., Crossman, A. T., Sullivan, L., Ferguson, M. A. J. & Urbaniak, M., 03/2012, In: Chemical Biology and Drug Design. 79, 3, p. 270-278 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. 2011
  14. Published

    Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei

    Abdelwahab, N. Z., Urbaniak, M. D., Ferguson, M. A. J. & Crossman, A. T., 1/05/2011, In: Carbohydrate Research. 346, 6, p. 708-714 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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