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Professor Paul McKean

Head of Department, Senior Lecturer

  1. Published

    A centriolar FGR1 oncogene partner-like protein required for paraflagellar rod assembly, but not axoneme assembly in African trypanosomes

    Harmer, J., Towers, K., Addison, M., Vaughan, S., Ginger, M. L. & McKean, P. G., 07/2018, In: Open biology. 8, 7, 13 p., 170218.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    A single amino acid determines the specificity of a monoclonal antibody which inhibits Plasmodium chabaudi AS in vivo.

    McKean, P. G., O'Dea, K. P. & Brown, K. N., 12/1993, In: Molecular and Biochemical Parasitology. 62, 2, p. 211-221 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    A single gene copy merozoite surface antigen and immune evasion?

    O’Dea, K. P., McKean, P. G., Jarra, W. & Brown, K. N., 04/1996, In: Parasite Immunology. 18, 4, p. 165-172 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    An alternative model for the role of RP2 in flagellum assembly in the African trypanosome: RP2 function in T. brucei

    Andre, J., Kerry, L., Qi, X., Hawkins, E., Drižytė, K., Ginger, M. & McKean, P., 3/01/2014, In: Journal of Biological Chemistry. 289, 1, p. 464 –475 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    An essential quality control mechanism at the eukaryotic basal body prior to intraflagellar transport.

    Stephan, A., Vaughan, S., Shaw, M. K., Gull, K. & McKean, P. G., 10/2007, In: Traffic. 8, 10, p. 1323-1330 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    An immunological and biochemical comparison of hookworm species.

    Pritchard, D. I., McKean, P. G. & Schad, G. A., 05/1990, In: Parasitology Today. 6, 5, p. 154-156 3 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Analysis of the trypanosome flagellar proteome using a combined electron transfer collisionally activated dissociation strategy.

    Hart, S. R., Wai Lau, K. W., Hao, Z., Broadhead, R., Portman, N., Huhmer, A., Gull, K., McKean, P. G., Hubbard, S. J. & Gaskell, S. J., 02/2009, In: Journal of The American Society for Mass Spectrometry. 20, 2, p. 167-175 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Antigenic cross-reactivity between Necator americanus and Ascaris lumbricoides in a community in Papua New Guinea infected predominantly with hookworm.

    Pritchard, D. I., Quinnell, R. J., McKean, P. G., Walsh, L., Leggett, K. V., Slater, A. F., Raiko, A., Dale, D. D. & Keymer, A. E., 07/1991, In: Transactions of The Royal Society of Tropical Medicine and Hygiene. 85, 4, p. 511-514 4 p.

    Research output: Contribution to Journal/MagazineJournal article

  9. Published

    Basal body and flagellum mutants reveal a rotational constraint of the central pair microtubules in the axonemes of trypanosomes.

    Gadelha, C., Wickstead, B., McKean, P. G. & Gull, K., 15/06/2006, In: Journal of Cell Science. 119, 12, p. 2405-2413 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Cell cycle synchronisation of Trypanosoma brucei by centrifugal counter-flow elutriation reveals the timing of nuclear and kinetoplast DNA replication

    Benz, C., Dondelinger, F., McKean, P. G. & Urbaniak, M. D., 14/12/2017, In: Scientific Reports. 7, 10 p., 17599.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Cell structure, cell division and cell cycle.

    Hammarton, T., Wickstead, B. & McKean, P. G., 2007, Trypanosomes : after the genome. Barry, D., McCulloch, R., Mottram, J. & Acosta-Serrano, A. (eds.). Wymondham: Horizon Bioscience, p. 239-280 42 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  12. Published

    Characterisation of a differentially expressed protein that shows an unusual localisation to intracellular membranes in Leishmania major.

    Kneupfer, E., Stierhof, Y. D., McKean, P. G. & Smith, D. F., 1/06/2001, In: Biochemical Journal. 356, 2, p. 335-344 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Characterisation of a second protein encoded by the differentially regulated LmcDNA16 gene family of Leishmania major.

    McKean, P. G., Delahay, R., Pimenta, P. F. & Smith, D. F., 04/1997, In: Molecular and Biochemical Parasitology. 85, 2, p. 221-231 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Combining RNA interference mutants and comparative proteomics to identify protein component interactions and dependencies in a eukaryotic flagellum.

    Portman, N., Lacomble, S., Thomas, B., McKean, P. G. & Gull, K., 02/2009, In: Journal of Biological Chemistry. 284, 9, p. 5610-5619 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Coordination of cell cycle progression and cytokinesis in Trypanosoma brucei.

    McKean, P. G., 12/2003, In: Current Opinion in Microbiology. 6, 6, p. 600-607 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Cuticle preparations from Necator americanus and their immunogenicity in the infected host.

    Pritchard, D. I., McKean, P. G. & Rogan, M. T., 04/1988, In: Molecular and Biochemical Parasitology. 28, 3, p. 275-283 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Cuticular collagens – a concealed target for immune attack in hookworms.

    Pritchard, D. I., McKean, P. G. & Rogan, M. T., 09/1988, In: Parasitology Today. 4, 9, p. 239-241 3 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Diversity in repeat-containing surface proteins of Leishmania major.

    McKean, P. G., Trenholme, K. R., Rangarajan, D., Keen, J. K. & Smith, D. F., 06/1997, In: Molecular and Biochemical Parasitology. 86, 2, p. 225-235 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Epidemiology and immunology of Necator americanus infection in a community in Papua New Guinea: humoral responses to excretory-secretory and cuticular collagen antigens.

    Pritchard, D. I., Quinnell, R. J., Slater, A. F., McKean, P. G., Dale, D. D., Raiko, A. & Keymer, A. E., 1990, In: Parasitology. 100, 2, p. 317-326 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Eukaryotic flagella: variations in form, function, and composition during evolution

    Moran, J., McKean, P. & Ginger, M., 1/12/2014, In: Bioscience. 64, 12, p. 1103-1114 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Flagellar motility is required for the viability of the bloodstream trypanosome.

    Broadhead, R., Dawe, H. R., Farr, H., Griffiths, S., Hart, S. R., Portman, N., Shaw, M. K., Ginger, M. L., Gaskell, S. J., McKean, P. G. & Gull, K., 9/03/2006, In: Nature. 440, 7081, p. 224-227 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Flagellum function and assembly during the Leishmania life cycle.

    Gluenz, E., Ginger, M. L. & McKean, P. G., 08/2010, In: Current Opinion in Microbiology. 13, 4, p. 473-479 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Hookworm (Necator americanus) infection and storage iron depletion.

    Pritchard, D. I., Quinnell, R. J., Moustafa, M., McKean, P. G., Slater, A. F., Raiko, A., Dale, D. D. & Keymer, A. E., 1991, In: Transactions of The Royal Society of Tropical Medicine and Hygiene. 85, 2, p. 235-238 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Identification and characterisation of a RAD51 gene from Leishmania major.

    McKean, P. G., Keen, J. G., Smith, D. F. & Benson, F. E., 07/2001, In: Molecular and Biochemical Parasitology. 115, 2, p. 209-216 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Modulation of flagellum attachment zone protein FLAM3 and regulation of the cell shape in Trypanosoma brucei life cycle transitions

    Sunter, J. D., Benz, C., Andre, J., Whipple, S., McKean, P. G., Gull, K., Ginger, M. L. & Lukeš, J., 15/08/2015, In: Journal of Cell Science. 128, 16, p. 3117-3130 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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