Home > Research > Projects > High-resolution spatiotemporal mapping of brain...
View graph of relations

High-resolution spatiotemporal mapping of brain and gut organismal death processes in C. elegans.

Project: Research

Description

1-year HHMI-funded Janelia Frams Visiting Scientist program, which included a 6-month secondment in the team of Dr Hari Shroff at the HHMI Janelia Farms.

The project aims to (1) leverage unique advantages of C. elegans as an ethical and powerful model to study organismal death processes in vivo (a field pioneered by Dr Benedetto during postdoctoral work at UCL) and the unique expertise in fast and gentle 4D live-imaging (diSPIM) and image-analysis of C. elegans from the Shroff laboratory to perform light-sheet microscopy experiments and process worm data (with possible help from the AIC and the scientific computing team, as needed), and (2) take advantage of the proximity with the Ahrens and Wang laboratories to establish collaborations on deciphering conserved aspects of death-associated neurological processes (Ahrens group) and cognitive frailty in old worms (Wang group).
StatusFinished
Effective start/end date17/07/2317/07/24

Project relations

Project relations

Activities

Facilities/Equipment

  • Tecan mNano+ plate based spectrophotometer

    Facility/Equipment: Equipment

  • Tecan Spark plate based spectrophotometer

    Facility/Equipment: Equipment

  • Zeiss Axiozoom V16 automated Macroscope

    Facility/Equipment: Equipment

  • Crest X-light V3 Spinning disk confocal Mircoscope

    Facility/Equipment: Equipment

Research outputs