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Results for Immunity, Innate

Publications & Outputs

  1. Induction of innate immunity and its perturbation by influenza viruses

    Goraya, M. U., Wang, S., Munir, M. & Chen, J-L., 10/2015, In: Protein and Cell. 6, 10, p. 712-721 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. The interferon response to intracellular DNA: why so many receptors?

    Unterholzner, L., 11/2013, In: Immunobiology. 218, 11, p. 1312-1321 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Tsoi, L. C., Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, J. E., Kang, H. M., Allen, M. H., McManus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Ståhle, M., Burden, A. D., Smith, C. H., Cork, M. J. & 31 others, Estivill, X., Bowcock, A. M., Krueger, G. G., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, F. O., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, R. D., Vukcevic, D., Spencer, C. C. A., Deloukas, P., Mrowietz, U., Schreiber, S., Weidinger, S., Koks, S., Kingo, K., Esko, T., Metspalu, A., Lim, H. W., Voorhees, J. J. & Collaborative Association Study of Psoriasis (CASP), 12/2012, In: Nature Genetics. 44, 12, p. 1341-1348 8 p.

    Research output: Contribution to journalLetterpeer-review

  4. Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor

    Jin, T., Perry, A., Jiang, J., Smith, P., Curry, J. A., Unterholzner, L., Jiang, Z., Horvath, G., Rathinam, V. A., Johnstone, R. W., Hornung, V., Latz, E., Bowie, A. G., Fitzgerald, K. A. & Xiao, T. S., 20/04/2012, In: Immunity. 36, 4, p. 561-571 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis

    Onoufriadis, A., Simpson, M. A., Pink, A. E., Di Meglio, P., Smith, C. H., Pullabhatla, V., Knight, J., Spain, S. L., Nestle, F. O., Burden, A. D., Capon, F., Trembath, R. C. & Barker, J. N. W. N., 9/09/2011, In: American Journal of Human Genetics. 89, 3, p. 432-437 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7

    Unterholzner, L., Sumner, R. P., Baran, M., Ren, H., Mansur, D. S., Bourke, N. M., Randow, F., Smith, G. L. & Bowie, A. G., 09/2011, In: PLoS Pathogens. 7, 9, e1002247.

    Research output: Contribution to journalJournal articlepeer-review

  7. IFI16 is an innate immune sensor for intracellular DNA

    Unterholzner, L., Keating, S. E., Baran, M., Horan, K. A., Jensen, S. B., Sharma, S., Sirois, C. M., Jin, T., Latz, E., Xiao, T. S., Fitzgerald, K. A., Paludan, S. R. & Bowie, A. G., 11/2010, In: Nature Immunology. 11, 11, p. 997-1004 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. TRIM proteins: another class of viral victims

    Munir, M., 20/04/2010, In: Science Signaling. 3, 118, jc2.

    Research output: Contribution to journalJournal articlepeer-review

  9. Viral evasion and subversion of pattern-recognition receptor signalling

    Bowie, A. G. & Unterholzner, L., 12/2008, In: Nature Immunology. 8, 12, p. 911-922 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. The interplay between viruses and innate immune signaling: recent insights and therapeutic opportunities

    Unterholzner, L. & Bowie, A. G., 1/02/2008, In: Biochemical Pharmacology. 75, 3, p. 589-602 14 p.

    Research output: Contribution to journalJournal articlepeer-review