Restoration of cerebral and systemic microvascular architecture in APP/PS1 transgenic mice following treatment with Liraglutide™

Kelly, P., McClean, P. L., Ackermann, M., Konerding, M. A., Holscher, C. & Mitchell, C. A., 02/2015, In: Microcirculation. 22, 2, p. 133-145 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease

Liu, W., Li, Y., Jalewa, J., Saunders-Wood, T., Li, L. & Hölscher, C., 2015, In: European Journal of Pharmacology. 765, p. 284-290 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Quantitative measurement of [Na+] and [K+] in postmortem human brain tissue indicates disturbances in subjects with Alzheimer's Disease and dementia with Lewy bodies

Graham, S. F., Nasarauddin, M. B., Carey, M., McGuinness, B., Holscher, C., Kehoe, P. G., Love, S., Passmore, A. P., Elliott, C. T., Meharg, A. & Green, B. D., 2015, In: Journal of Alzheimer's Disease. 44, 3, p. 851-857 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Comparison of the independent and combined effects of sub-chronic therapy with metformin and a stable GLP-1 receptor agonist on cognitive function, hippocampal synaptic plasticity and metabolic control in high-fat fed mice

Lennox, R., Porter, D. W., Flatt, P. R., Holscher, C., Irwin, N. & Gault, V. A., 11/2014, In: Neuropharmacology. 86, p. 22-30 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease

McClean, P. L. & Holscher, C., 11/2014, In: Neuropharmacology. 86, p. 241-258 18 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Lixisenatide rescues spatial memory and synaptic plasticity from amyloid β protein-induced impairments in rats

Cai, H-Y., Hölscher, C., Yue, X-H., Zhang, S-X., Wang, X-H., Qiao, F., Yang, W. & Qi, J-S., 26/09/2014, In: Neuroscience. 277, p. 6-13 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Metabolic signatures of human Alzheimer's disease (AD): H-1 NMR analysis of the polar metabolome of post-mortem brain tissue

Graham, S. F., Holscher, C. & Green, B. D., 08/2014, In: Metabolomics. 10, 4, p. 744-753 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Peptide drugs that have been developed to treat type 2 diabetes show neuroprotective effects

Holscher, C., 06/2014, In: Regulatory Peptides. 192-193, p. 55-56 2 p.

Research output: Contribution to Journal/Magazine › Editorial › peer-review

Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases

Holscher, C., 1/04/2014, In: Journal of Endocrinology. 221, p. T31-T41 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases

Hölscher, C., 1/04/2014, In: Biochemical Society Transactions. 42, 2, p. 593-599 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Neural circuit interactions between the dorsal raphe nucleus and the lateral hypothalamus: an experimental and computational study

Jalewa, J., Joshi, A., McGinnity, T. M., Prasad, G., Wong-Lin, K. & Hölscher, C., 6/02/2014, In: PLoS ONE. 9, 2, 16 p., e88003.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

First clinical data of the neuroprotective effects of nasal insulin application in patients with Alzheimer's disease

Hölscher, C., 02/2014, In: Alzheimer's and Dementia. 10, 1 Supplement, p. S33-37 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Neuroprotective and anti-apoptotic effects of Liraglutide on SH-SY5Y cells exposed to Methylglyoxal stress

Sharma, M., Jalewa, J. & Hölscher, C., 02/2014, In: Journal of Neurochemistry. 128, 3, p. 459-471 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The incretin hormones glucagonlike peptide 1 and glucose-dependent insulinotropic polypeptide are neuroprotective in mouse models of Alzheimer's disease

Hölscher, C., 02/2014, In: Alzheimer's and Dementia. 10, 1 Supplement, p. S47-54 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Age-associated changes of brain copper, iron, and zinc in Alzheimer's disease and dementia with Lewy bodies

Graham, S. F., Nasaruddin, M. B., Carey, M., Holscher, C., McGuinness, B., Kehoe, P. G., Love, S., Passmore, P., Elliott, C. T., Meharg, A. A. & Green, B. D., 2014, In: Journal of Alzheimer's Disease. 42, 4, p. 1407-1413 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-Amyloid oligomers in mice and monkeys

Lourenco, M. V., Clarke, J. R., Frozza, R. L., Bomfim, T. R., Forny-Germano, L., Batista, A. F., Sathler, L. B., Brito-Moreira, J., Amaral, O. B., Silva, C. A., Freitas-Correa, L., Espírito-Santo, S., Campello-Costa, P., Houzel, J-C., Klein, W. L., Holscher, C., Carvalheira, J. B., Silva, A. M., Velloso, L. A., Munoz, D. P., & 2 othersFerreira, S. T. & De Felice, F. G., 3/12/2013, In: Cell Metabolism. 18, 6, p. 831-843 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

New animal models of Alzheimer's disease that display insulin desensitization in the brain

Gao, C., Liu, Y., Li, L. & Hölscher, C., 12/2013, In: Reviews in the Neurosciences. 24, 6, p. 607-615 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

H-1 NMR metabolomics investigation of an Alzheimer's disease (AD) mouse model pinpoints important biochemical disturbances in brain and plasma

Graham, S. F., Holscher, C., McClean, P., Elliot, C. T. & Green, B. D., 10/2013, In: Metabolomics. 9, 5, p. 974-983 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Intranasal insulin as a treatment for Alzheimer’s Disease: a review of basic research and clinical evidence

Freiherr, J., Hallschmid, M., Frey, W., Brünner, Y., Chapman, C., Holscher, C., Craft, S., De Felice, F. & Benedict, C., 07/2013, In: CNS Drugs. 27, 7, p. 505-514 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Liraglutide improves hippocampal synaptic plasticity associated with increased expression of Mash1 in ob/ob mice

Porter, W. D., Flatt, P. R., Hölscher, C. & Gault, V. A., 05/2013, In: International Journal of Obesity. 37, 5, p. 678-684 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Neuroprotective effects of D-Ala2GIP on Alzheimer’s disease biomarkers in an APP/PS1 mouse model

Faivre, E. & Holscher, C., 19/04/2013, In: Alzheimer's Research and Therapy. 5, p. 20-29 10 p., 20.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

D-Ala2GIP facilitated synaptic plasticity and reduces plaque load in aged wild type mice and in an Alzheimer’s disease mouse model

Faivre, E. & Holscher, C., 8/04/2013, In: Journal of Alzheimer's Disease. 35, 2, p. 267-283 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Val⁸-GLP-1 remodels synaptic activity and intracellular calcium homeostasis impaired by amyloid β peptide in rats

Wang, X-H., Yang, W., Hölscher, C., Wang, Z-J., Cai, H-Y., Li, Q-S. & Qi, J-S., 04/2013, In: Journal of Neuroscience Research. 91, 4, p. 568-577 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Chronic treatment with the GLP1 analogue liraglutide increases cell proliferation and differentiation into neurons in an AD mouse model

Parthsarathy, V. & Holscher, C., 11/03/2013, In: PLoS ONE. 8, 3, e58784.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Beneficial actions of glucagon-like peptide 1 (GLP-1) on hippocampal synaptic plasticity, gene expression, oxidative stress and inflammation in mice with diet-induced obesity and insulin resistance

Gault, V., Lennox, R., Porter, D., Holscher, C. & Flatt, P., 03/2013, In: Diabetic Medicine. 30, Supplement 1, p. 4 1 p., A9 (P99).

Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review