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Dr Leonie Unterholzner

Research Fellow/Lecturer

  1. Published

    IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

    Almine, J. F., O'Hare, C. A. J., Dunphy, G., Haga, I. R., Naik, R. J., Atrih, A., Connolly, D. J., Taylor, J., Kelsall, I. R., Bowie, A. G., Beard, P. M. & Unterholzner, L., 13/02/2017, In : Nature Communications. 8, 14392.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex

    Bono, F., Ebert, J., Unterholzner, L., Güttler, T., Izaurralde, E. & Conti, E., 03/2004, In : EMBO Reports. 5, 3, p. 304-310 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Viral evasion and subversion of pattern-recognition receptor signalling

    Bowie, A. G. & Unterholzner, L., 12/2008, In : Nature Immunology. 8, 12, p. 911-922 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Non-canonical activation of the DNA sensing adaptor STING by ATM and IFI16 mediates NF-κB signalling after nuclear DNA damage

    Dunphy, G., Flannery, S., Almine, J., Connolly, D., Paulus, C., Jønsson, K., Jakobsen, M., Nevels, M., Bowie, A. & Unterholzner, L., 6/09/2018, In : Molecular Cell. 71, 5, p. 745-760 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway

    Fukuhara, N., Ebert, J., Unterholzner, L., Lindner, D., Izaurralde, E. & Conti, E., 18/02/2005, In : Molecular Cell. 17, 4, p. 537-547 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways

    Gatfield, D., Unterholzner, L., Ciccarelli, F. D., Bork, P. & Izaurralde, E., 1/08/2003, In : EMBO Journal. 22, 15, p. 3960-3970 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

    Horan, K. A., Hansen, K., Jakobsen, M. R., Holm, C. K., Søby, S., Unterholzner, L., Thompson, M., West, J. A., Iversen, M. B., Rasmussen, S. B., Ellermann-Eriksen, S., Kurt-Jones, E., Landolfo, S., Damania, B., Melchjorsen, J., Bowie, A. G., Fitzgerald, K. A. & Paludan, S. R., 1/03/2013, In : Journal of Immunology. 190, 5, p. 2311-2319 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor

    Jin, T., Perry, A., Jiang, J., Smith, P., Curry, J. A., Unterholzner, L., Jiang, Z., Horvath, G., Rathinam, V. A., Johnstone, R. W., Hornung, V., Latz, E., Bowie, A. G., Fitzgerald, K. A. & Xiao, T. S., 20/04/2012, In : Immunity. 36, 4, p. 561-571 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence

    Mansur, D. S., Maluquer de Motes, C., Unterholzner, L., Sumner, R. P., Ferguson, B. J., Ren, H., Strnadova, P., Bowie, A. G. & Smith, G. L., 02/2013, In : PLoS Pathogens. 9, 2, e1003183.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    The interferon response to intracellular DNA: why so many receptors?

    Unterholzner, L., 11/2013, In : Immunobiology. 218, 11, p. 1312-1321 10 p.

    Research output: Contribution to journalJournal articlepeer-review

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