A study on interference management schemes in wireless multi-user networks is presented. We analyze the interference management problem in cellular networks and show that interference management is an optimization problem, for which we propose a general formulation. Using this general formulations we show that different interference management approaches are either exact or approximated solutions to this optimization problem. For each radio resource management technique, we provide a general overview and discuss its relation vis-a-vie other interference management techniques. As a case study, we then apply the proposed general formulation on the interference management in OFDM wireless networks and show that it results in a joint transmit scheduling and dynamic sub-carrier and power allocation scheme. A polynomial-time heuristic algorithm is also proposed to solve the formulated optimization problem. The distinguishing feature of the proposed scheme is that it gives in one shot, the transmission scheduling, the sub-carriers assigned to each user, and the power allocated to each sub-carrier, based on a fair and efficient framework while satisfying the delay requirements of real-time users.