Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - An Auxetic structure configured as oesophageal stent with potential to be used for palliative treatment of oesophageal cancer; Development and in vitro mechanical analysis
AU - Ali, M.N.
AU - Rehman, I.U.
PY - 2011
Y1 - 2011
N2 - Oesophageal cancer is the ninth leading cause of malignant cancer death and its prognosis remains poor. Dysphagia which is an inability to swallow is a presenting symptom of oesophageal cancer and is indicative of incurability. The goal of this study was to design and manufacture an Auxetic structure film and to configure this film as an Auxetic stent for the palliative treatment of oesophageal cancer, and for the prevention of dysphagia. Polypropylene was used as a material for its flexibility and non-toxicity. The Auxetic (rotating-square geometry) structure was made by laser cutting the polypropylene film. This flat structure was welded together to form a tubular form (stent), by an adjustable temperature control soldering iron station: following this, an annealing process was also carried out to ease any material stresses. Poisson's ratio was estimated and elastic and plastic deformation of the Auxetic structure was evaluated. The elastic and plastic deformation behaviours of the Auxetic polypropylene film were evaluated by applying repetitive uniaxial tensile loads. Observation of the structure showed that it was initially elastically deformed, thereafter plastic deformation occurred. This research discusses a novel way of fabricating an Auxetic structure (rotating-squares connected together through hinges) on Polypropylene films, by estimating the Poisson's ratio and evaluating the plastic deformation relevant to the expansion behaviour of an Auxetic stent within the oesophageal lumen. © 2011 Springer Science+Business Media, LLC.
AB - Oesophageal cancer is the ninth leading cause of malignant cancer death and its prognosis remains poor. Dysphagia which is an inability to swallow is a presenting symptom of oesophageal cancer and is indicative of incurability. The goal of this study was to design and manufacture an Auxetic structure film and to configure this film as an Auxetic stent for the palliative treatment of oesophageal cancer, and for the prevention of dysphagia. Polypropylene was used as a material for its flexibility and non-toxicity. The Auxetic (rotating-square geometry) structure was made by laser cutting the polypropylene film. This flat structure was welded together to form a tubular form (stent), by an adjustable temperature control soldering iron station: following this, an annealing process was also carried out to ease any material stresses. Poisson's ratio was estimated and elastic and plastic deformation of the Auxetic structure was evaluated. The elastic and plastic deformation behaviours of the Auxetic polypropylene film were evaluated by applying repetitive uniaxial tensile loads. Observation of the structure showed that it was initially elastically deformed, thereafter plastic deformation occurred. This research discusses a novel way of fabricating an Auxetic structure (rotating-squares connected together through hinges) on Polypropylene films, by estimating the Poisson's ratio and evaluating the plastic deformation relevant to the expansion behaviour of an Auxetic stent within the oesophageal lumen. © 2011 Springer Science+Business Media, LLC.
KW - Annealing process
KW - Elastic and plastic deformation
KW - In-vitro
KW - Laser cutting
KW - Malignant cancers
KW - Material stress
KW - Mechanical analysis
KW - Non-toxicity
KW - Oesophageal stent
KW - Poisson's ratio
KW - Poly-propylene film
KW - Structure films
KW - Tensile loads
KW - Diseases
KW - Metallic films
KW - Plastic deformation
KW - Plastic films
KW - Poisson ratio
KW - Rotation
KW - Thermoplastics
KW - Polypropylenes
KW - polypropylene
KW - article
KW - auxetic stent
KW - cancer palliative therapy
KW - dysphagia
KW - esophagus cancer
KW - geometry
KW - in vitro study
KW - laser
KW - mechanical stress
KW - priority journal
KW - stent
KW - temperature
KW - tensile strength
KW - Biocompatible Materials
KW - Esophageal Neoplasms
KW - Humans
KW - Materials Testing
KW - Microscopy, Electron, Scanning
KW - Palliative Care
KW - Stents
KW - Surface Properties
U2 - 10.1007/s10856-011-4436-y
DO - 10.1007/s10856-011-4436-y
M3 - Journal article
VL - 22
SP - 2573
EP - 2581
JO - Journal of Materials Science: Materials in Medicine
JF - Journal of Materials Science: Materials in Medicine
SN - 0957-4530
IS - 11
ER -