An Auxetic structure configured as oesophageal stent with potential to be used for palliative treatment of oesophageal cancer; Development and in vitro mechanical analysis

School of Engineering

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https://doi.org/10.1007/s10856-011-4436-y
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An Auxetic structure configured as oesophageal stent with potential to be used for palliative treatment of oesophageal cancer; Development and in vitro mechanical analysis. / Ali, M.N.; Rehman, I.U.
In: Journal of Materials Science: Materials in Medicine, Vol. 22, No. 11, 2011, p. 2573-2581.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bibtex

@article{6fe254e6cc2f445d8f8a0481e2ba6b44,

title = "An Auxetic structure configured as oesophageal stent with potential to be used for palliative treatment of oesophageal cancer; Development and in vitro mechanical analysis",

abstract = "Oesophageal cancer is the ninth leading cause of malignant cancer death and its prognosis remains poor. Dysphagia which is an inability to swallow is a presenting symptom of oesophageal cancer and is indicative of incurability. The goal of this study was to design and manufacture an Auxetic structure film and to configure this film as an Auxetic stent for the palliative treatment of oesophageal cancer, and for the prevention of dysphagia. Polypropylene was used as a material for its flexibility and non-toxicity. The Auxetic (rotating-square geometry) structure was made by laser cutting the polypropylene film. This flat structure was welded together to form a tubular form (stent), by an adjustable temperature control soldering iron station: following this, an annealing process was also carried out to ease any material stresses. Poisson's ratio was estimated and elastic and plastic deformation of the Auxetic structure was evaluated. The elastic and plastic deformation behaviours of the Auxetic polypropylene film were evaluated by applying repetitive uniaxial tensile loads. Observation of the structure showed that it was initially elastically deformed, thereafter plastic deformation occurred. This research discusses a novel way of fabricating an Auxetic structure (rotating-squares connected together through hinges) on Polypropylene films, by estimating the Poisson's ratio and evaluating the plastic deformation relevant to the expansion behaviour of an Auxetic stent within the oesophageal lumen. {\textcopyright} 2011 Springer Science+Business Media, LLC.",

keywords = "Annealing process, Elastic and plastic deformation, In-vitro, Laser cutting, Malignant cancers, Material stress, Mechanical analysis, Non-toxicity, Oesophageal stent, Poisson's ratio, Poly-propylene film, Structure films, Tensile loads, Diseases, Metallic films, Plastic deformation, Plastic films, Poisson ratio, Rotation, Thermoplastics, Polypropylenes, polypropylene, article, auxetic stent, cancer palliative therapy, dysphagia, esophagus cancer, geometry, in vitro study, laser, mechanical stress, priority journal, stent, temperature, tensile strength, Biocompatible Materials, Esophageal Neoplasms, Humans, Materials Testing, Microscopy, Electron, Scanning, Palliative Care, Stents, Surface Properties",

author = "M.N. Ali and I.U. Rehman",

year = "2011",

doi = "10.1007/s10856-011-4436-y",

language = "English",

volume = "22",

pages = "2573--2581",

journal = "Journal of Materials Science: Materials in Medicine",

issn = "0957-4530",

publisher = "Kluwer Academic Publishers",

number = "11",

}

RIS

TY - JOUR

T1 - An Auxetic structure configured as oesophageal stent with potential to be used for palliative treatment of oesophageal cancer; Development and in vitro mechanical analysis

AU - Ali, M.N.

AU - Rehman, I.U.

PY - 2011

Y1 - 2011

N2 - Oesophageal cancer is the ninth leading cause of malignant cancer death and its prognosis remains poor. Dysphagia which is an inability to swallow is a presenting symptom of oesophageal cancer and is indicative of incurability. The goal of this study was to design and manufacture an Auxetic structure film and to configure this film as an Auxetic stent for the palliative treatment of oesophageal cancer, and for the prevention of dysphagia. Polypropylene was used as a material for its flexibility and non-toxicity. The Auxetic (rotating-square geometry) structure was made by laser cutting the polypropylene film. This flat structure was welded together to form a tubular form (stent), by an adjustable temperature control soldering iron station: following this, an annealing process was also carried out to ease any material stresses. Poisson's ratio was estimated and elastic and plastic deformation of the Auxetic structure was evaluated. The elastic and plastic deformation behaviours of the Auxetic polypropylene film were evaluated by applying repetitive uniaxial tensile loads. Observation of the structure showed that it was initially elastically deformed, thereafter plastic deformation occurred. This research discusses a novel way of fabricating an Auxetic structure (rotating-squares connected together through hinges) on Polypropylene films, by estimating the Poisson's ratio and evaluating the plastic deformation relevant to the expansion behaviour of an Auxetic stent within the oesophageal lumen. © 2011 Springer Science+Business Media, LLC.

AB - Oesophageal cancer is the ninth leading cause of malignant cancer death and its prognosis remains poor. Dysphagia which is an inability to swallow is a presenting symptom of oesophageal cancer and is indicative of incurability. The goal of this study was to design and manufacture an Auxetic structure film and to configure this film as an Auxetic stent for the palliative treatment of oesophageal cancer, and for the prevention of dysphagia. Polypropylene was used as a material for its flexibility and non-toxicity. The Auxetic (rotating-square geometry) structure was made by laser cutting the polypropylene film. This flat structure was welded together to form a tubular form (stent), by an adjustable temperature control soldering iron station: following this, an annealing process was also carried out to ease any material stresses. Poisson's ratio was estimated and elastic and plastic deformation of the Auxetic structure was evaluated. The elastic and plastic deformation behaviours of the Auxetic polypropylene film were evaluated by applying repetitive uniaxial tensile loads. Observation of the structure showed that it was initially elastically deformed, thereafter plastic deformation occurred. This research discusses a novel way of fabricating an Auxetic structure (rotating-squares connected together through hinges) on Polypropylene films, by estimating the Poisson's ratio and evaluating the plastic deformation relevant to the expansion behaviour of an Auxetic stent within the oesophageal lumen. © 2011 Springer Science+Business Media, LLC.

KW - Annealing process

KW - Elastic and plastic deformation

KW - In-vitro

KW - Laser cutting

KW - Malignant cancers

KW - Material stress

KW - Mechanical analysis

KW - Non-toxicity

KW - Oesophageal stent

KW - Poisson's ratio

KW - Poly-propylene film

KW - Structure films

KW - Tensile loads

KW - Diseases

KW - Metallic films

KW - Plastic deformation

KW - Plastic films

KW - Poisson ratio

KW - Rotation

KW - Thermoplastics

KW - Polypropylenes

KW - polypropylene

KW - article

KW - auxetic stent

KW - cancer palliative therapy

KW - dysphagia

KW - esophagus cancer

KW - geometry

KW - in vitro study

KW - laser

KW - mechanical stress

KW - priority journal

KW - stent

KW - temperature

KW - tensile strength

KW - Biocompatible Materials

KW - Esophageal Neoplasms

KW - Humans

KW - Materials Testing

KW - Microscopy, Electron, Scanning

KW - Palliative Care

KW - Stents

KW - Surface Properties

U2 - 10.1007/s10856-011-4436-y

DO - 10.1007/s10856-011-4436-y

M3 - Journal article

VL - 22

SP - 2573

EP - 2581

JO - Journal of Materials Science: Materials in Medicine

JF - Journal of Materials Science: Materials in Medicine

SN - 0957-4530

IS - 11

ER -

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