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Edible unclonable functions

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Edible unclonable functions. / Leem, Jung Woo; Kim, Min Seok; Choi, Seung Ho; Kim, Seong-Ryul; Kim, Seong-Wan; Song, Young Min; Young, Robert; Kim, Young L.

In: Nature Communications, Vol. 11, 328, 16.01.2020.

Research output: Contribution to journalJournal article

Harvard

Leem, JW, Kim, MS, Choi, SH, Kim, S-R, Kim, S-W, Song, YM, Young, R & Kim, YL 2020, 'Edible unclonable functions', Nature Communications, vol. 11, 328. https://doi.org/10.1038/s41467-019-14066-5

APA

Leem, J. W., Kim, M. S., Choi, S. H., Kim, S-R., Kim, S-W., Song, Y. M., Young, R., & Kim, Y. L. (2020). Edible unclonable functions. Nature Communications, 11, [328]. https://doi.org/10.1038/s41467-019-14066-5

Vancouver

Leem JW, Kim MS, Choi SH, Kim S-R, Kim S-W, Song YM et al. Edible unclonable functions. Nature Communications. 2020 Jan 16;11. 328. https://doi.org/10.1038/s41467-019-14066-5

Author

Leem, Jung Woo ; Kim, Min Seok ; Choi, Seung Ho ; Kim, Seong-Ryul ; Kim, Seong-Wan ; Song, Young Min ; Young, Robert ; Kim, Young L. / Edible unclonable functions. In: Nature Communications. 2020 ; Vol. 11.

Bibtex

@article{31e135da4117463b92ab007e74bb05e4,
title = "Edible unclonable functions",
abstract = "Counterfeit medicines are a fundamental security problem. Counterfeiting medication poses a tremendous threat to patient safety, public health, and the economy in developed and less developed countries. Current solutions are often vulnerable due to the limited security levels. We propose that the highest protection against counterfeit medicines would be a combination of a physically unclonable function (PUF) with on-dose authentication. A PUF can provide a digital fingerprint with multiple pairs of input challenges and output responses. On-dose authentication can verify every individual pill without removing the identification tag. Here, we report on-dose PUFs that can be directly attached onto the surface of medicines, be swallowed, and digested. Fluorescent proteins and silk proteins serve as edible photonic biomaterials and the photoluminescent properties provide parametric support of challenge-response pairs. Such edible cryptographic primitives can play an important role in pharmaceutical anti-counterfeiting and other security applications requiring immediate destruction or vanishing features.",
keywords = "PUF, physical security, anti-counterfeit, tag",
author = "Leem, {Jung Woo} and Kim, {Min Seok} and Choi, {Seung Ho} and Seong-Ryul Kim and Seong-Wan Kim and Song, {Young Min} and Robert Young and Kim, {Young L.}",
year = "2020",
month = jan
day = "16",
doi = "10.1038/s41467-019-14066-5",
language = "English",
volume = "11",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",

}

RIS

TY - JOUR

T1 - Edible unclonable functions

AU - Leem, Jung Woo

AU - Kim, Min Seok

AU - Choi, Seung Ho

AU - Kim, Seong-Ryul

AU - Kim, Seong-Wan

AU - Song, Young Min

AU - Young, Robert

AU - Kim, Young L.

PY - 2020/1/16

Y1 - 2020/1/16

N2 - Counterfeit medicines are a fundamental security problem. Counterfeiting medication poses a tremendous threat to patient safety, public health, and the economy in developed and less developed countries. Current solutions are often vulnerable due to the limited security levels. We propose that the highest protection against counterfeit medicines would be a combination of a physically unclonable function (PUF) with on-dose authentication. A PUF can provide a digital fingerprint with multiple pairs of input challenges and output responses. On-dose authentication can verify every individual pill without removing the identification tag. Here, we report on-dose PUFs that can be directly attached onto the surface of medicines, be swallowed, and digested. Fluorescent proteins and silk proteins serve as edible photonic biomaterials and the photoluminescent properties provide parametric support of challenge-response pairs. Such edible cryptographic primitives can play an important role in pharmaceutical anti-counterfeiting and other security applications requiring immediate destruction or vanishing features.

AB - Counterfeit medicines are a fundamental security problem. Counterfeiting medication poses a tremendous threat to patient safety, public health, and the economy in developed and less developed countries. Current solutions are often vulnerable due to the limited security levels. We propose that the highest protection against counterfeit medicines would be a combination of a physically unclonable function (PUF) with on-dose authentication. A PUF can provide a digital fingerprint with multiple pairs of input challenges and output responses. On-dose authentication can verify every individual pill without removing the identification tag. Here, we report on-dose PUFs that can be directly attached onto the surface of medicines, be swallowed, and digested. Fluorescent proteins and silk proteins serve as edible photonic biomaterials and the photoluminescent properties provide parametric support of challenge-response pairs. Such edible cryptographic primitives can play an important role in pharmaceutical anti-counterfeiting and other security applications requiring immediate destruction or vanishing features.

KW - PUF

KW - physical security

KW - anti-counterfeit

KW - tag

U2 - 10.1038/s41467-019-14066-5

DO - 10.1038/s41467-019-14066-5

M3 - Journal article

VL - 11

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 328

ER -