Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Forearm bone geometry and mineral content in UK women of European and South-Asian origin
AU - Ward, K. A.
AU - Roy, D. K.
AU - Pye, S. R.
AU - O'Neill, T. W.
AU - Berry, J. L.
AU - Swarbrick, C. M.
AU - Silman, A. J.
AU - Adams, J. E.
PY - 2007/7
Y1 - 2007/7
N2 - Ethnic variation in areal bone mineral density (BMD) has been well documented. Such variation may, however, reflects differences in bone geometry rather than volumetric BMD (vBMD). The aim of the study was to compare bone geometry, mineral content (BMC) and vBMD in two ethnic groups, and study the influence of body size, physical activity, reproductive variables, 25 hydroxy-vitamin D (25(OH)D) and parathormone (PTH) status on any observed differences. The data were from a population-based, cross-sectional survey of peak bone mass in South Asian and European women, the population consisted 230 pre-menopausal South Asian (n = 118, mean age 28.6 ± 4.6 years) and European (n = 112, mean age 30 ± 4.3 years) women of UK origin. Women who participated completed an interviewer assisted questionnaire, had blood taken for assessment of 25(OH)D and PTH and had measurements of their distal (4%) and diaphyseal (50%) radius geometry, BMC and vBMD using peripheral quantitative computed tomography. At the 50% radius, South Asians had lower vBMD (p
AB - Ethnic variation in areal bone mineral density (BMD) has been well documented. Such variation may, however, reflects differences in bone geometry rather than volumetric BMD (vBMD). The aim of the study was to compare bone geometry, mineral content (BMC) and vBMD in two ethnic groups, and study the influence of body size, physical activity, reproductive variables, 25 hydroxy-vitamin D (25(OH)D) and parathormone (PTH) status on any observed differences. The data were from a population-based, cross-sectional survey of peak bone mass in South Asian and European women, the population consisted 230 pre-menopausal South Asian (n = 118, mean age 28.6 ± 4.6 years) and European (n = 112, mean age 30 ± 4.3 years) women of UK origin. Women who participated completed an interviewer assisted questionnaire, had blood taken for assessment of 25(OH)D and PTH and had measurements of their distal (4%) and diaphyseal (50%) radius geometry, BMC and vBMD using peripheral quantitative computed tomography. At the 50% radius, South Asians had lower vBMD (p
KW - 25(OH)D
KW - Bone geometry
KW - Ethnicity
KW - Peripheral quantitative computed tomography
KW - Vitamin D
KW - Volumetric bone mineral density
U2 - 10.1016/j.bone.2007.03.013
DO - 10.1016/j.bone.2007.03.013
M3 - Journal article
VL - 41
SP - 117
EP - 121
JO - Bone
JF - Bone
SN - 8756-3282
IS - 1
ER -