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Forearm bone geometry and mineral content in UK women of European and South-Asian origin

Research output: Contribution to journalJournal articlepeer-review

  • K. A. Ward
  • D. K. Roy
  • S. R. Pye
  • T. W. O'Neill
  • J. L. Berry
  • C. M. Swarbrick
  • A. J. Silman
  • J. E. Adams
<mark>Journal publication date</mark>07/2007
Issue number1
Number of pages5
Pages (from-to)117-121
Publication StatusPublished
<mark>Original language</mark>English


Ethnic variation in areal bone mineral density (BMD) has been well documented. Such variation may, however, reflects differences in bone geometry rather than volumetric BMD (vBMD). The aim of the study was to compare bone geometry, mineral content (BMC) and vBMD in two ethnic groups, and study the influence of body size, physical activity, reproductive variables, 25 hydroxy-vitamin D (25(OH)D) and parathormone (PTH) status on any observed differences. The data were from a population-based, cross-sectional survey of peak bone mass in South Asian and European women, the population consisted 230 pre-menopausal South Asian (n = 118, mean age 28.6 ± 4.6 years) and European (n = 112, mean age 30 ± 4.3 years) women of UK origin. Women who participated completed an interviewer assisted questionnaire, had blood taken for assessment of 25(OH)D and PTH and had measurements of their distal (4%) and diaphyseal (50%) radius geometry, BMC and vBMD using peripheral quantitative computed tomography. At the 50% radius, South Asians had lower vBMD (p