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Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion

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Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion. / Hardy, John G.; Pfaff, Andre; Leal-Egana, Aldo et al.
In: Macromolecular Bioscience , Vol. 14, No. 7, 07.2014, p. 936-942.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Hardy, JG, Pfaff, A, Leal-Egana, A, Mueller, AHE & Scheibel, TR 2014, 'Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion', Macromolecular Bioscience , vol. 14, no. 7, pp. 936-942. https://doi.org/10.1002/mabi.201400020

APA

Hardy, J. G., Pfaff, A., Leal-Egana, A., Mueller, A. H. E., & Scheibel, T. R. (2014). Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion. Macromolecular Bioscience , 14(7), 936-942. https://doi.org/10.1002/mabi.201400020

Vancouver

Hardy JG, Pfaff A, Leal-Egana A, Mueller AHE, Scheibel TR. Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion. Macromolecular Bioscience . 2014 Jul;14(7):936-942. Epub 2014 Apr 2. doi: 10.1002/mabi.201400020

Author

Hardy, John G. ; Pfaff, Andre ; Leal-Egana, Aldo et al. / Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion. In: Macromolecular Bioscience . 2014 ; Vol. 14, No. 7. pp. 936-942.

Bibtex

@article{57e7171d79764aa3bb9d9d377834a2c5,
title = "Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion",
abstract = "Silk protein-based materials are promising biomaterials for application as tissue scaffolds, due to their processability, biocompatibility, and biodegradability. The preparation of films composed of an engineered spider silk protein (eADF4(C16)) and their functionalization with glycopolymers are described. The glycopolymers bind proteins found in the extracellular matrix, providing a biomimetic coating on the films that improves cell adhesion to the surfaces of engineered spider silk films. Such silk-based materials have potential as coatings for degradable implantable devices.",
keywords = "POLYMERS, RGD, BIOMATERIAL, SURFACES, COATINGS, collagen type 1 adhesin, Laminin, Biomaterials, Chemistry(all)",
author = "Hardy, {John G.} and Andre Pfaff and Aldo Leal-Egana and Mueller, {Axel H. E.} and Scheibel, {Thomas R.}",
year = "2014",
month = jul,
doi = "10.1002/mabi.201400020",
language = "English",
volume = "14",
pages = "936--942",
journal = "Macromolecular Bioscience ",
issn = "1616-5187",
publisher = "Wiley-VCH Verlag",
number = "7",

}

RIS

TY - JOUR

T1 - Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion

AU - Hardy, John G.

AU - Pfaff, Andre

AU - Leal-Egana, Aldo

AU - Mueller, Axel H. E.

AU - Scheibel, Thomas R.

PY - 2014/7

Y1 - 2014/7

N2 - Silk protein-based materials are promising biomaterials for application as tissue scaffolds, due to their processability, biocompatibility, and biodegradability. The preparation of films composed of an engineered spider silk protein (eADF4(C16)) and their functionalization with glycopolymers are described. The glycopolymers bind proteins found in the extracellular matrix, providing a biomimetic coating on the films that improves cell adhesion to the surfaces of engineered spider silk films. Such silk-based materials have potential as coatings for degradable implantable devices.

AB - Silk protein-based materials are promising biomaterials for application as tissue scaffolds, due to their processability, biocompatibility, and biodegradability. The preparation of films composed of an engineered spider silk protein (eADF4(C16)) and their functionalization with glycopolymers are described. The glycopolymers bind proteins found in the extracellular matrix, providing a biomimetic coating on the films that improves cell adhesion to the surfaces of engineered spider silk films. Such silk-based materials have potential as coatings for degradable implantable devices.

KW - POLYMERS

KW - RGD

KW - BIOMATERIAL

KW - SURFACES

KW - COATINGS

KW - collagen type 1 adhesin

KW - Laminin

KW - Biomaterials

KW - Chemistry(all)

U2 - 10.1002/mabi.201400020

DO - 10.1002/mabi.201400020

M3 - Journal article

VL - 14

SP - 936

EP - 942

JO - Macromolecular Bioscience

JF - Macromolecular Bioscience

SN - 1616-5187

IS - 7

ER -