Final published version
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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Gold nanoparticles as a substrate in bio-analytical near-infrared surface-enhanced Raman spectroscopy
AU - Butler, Holly J.
AU - Fogarty, Simon W.
AU - Kerns, Jemma G.
AU - Martin-Hirsch, Pierre L.
AU - Fullwood, Nigel J.
AU - Martin, Francis L.
PY - 2015
Y1 - 2015
N2 - As biospectroscopy techniques continue to be developed for screening or diagnosis within a point-ofcare setting, an important development for this field will be high-throughput optimization. For many of these techniques, it is therefore necessary to adapt and develop parameters to generate a robust yet simple approach delivering high-quality spectra from biological samples. Specifically, this is important for surface-enhanced Raman spectroscopy (SERS) wherein there are multiple variables that can be optimised to achieve an enhancement of the Raman signal from a sample. One hypothesis is that "large" diameter (>100 nm) gold nanoparticles provide a greater enhancement at near-infrared (NIR) and infrared (IR) wavelengths than those
AB - As biospectroscopy techniques continue to be developed for screening or diagnosis within a point-ofcare setting, an important development for this field will be high-throughput optimization. For many of these techniques, it is therefore necessary to adapt and develop parameters to generate a robust yet simple approach delivering high-quality spectra from biological samples. Specifically, this is important for surface-enhanced Raman spectroscopy (SERS) wherein there are multiple variables that can be optimised to achieve an enhancement of the Raman signal from a sample. One hypothesis is that "large" diameter (>100 nm) gold nanoparticles provide a greater enhancement at near-infrared (NIR) and infrared (IR) wavelengths than those
KW - SILVER NANOPARTICLES
KW - SCATTERING
KW - SERS
KW - CELLS
KW - SHAPE
KW - CANCER
KW - SIZE
U2 - 10.1039/c4an01899k
DO - 10.1039/c4an01899k
M3 - Journal article
VL - 140
SP - 3090
EP - 3097
JO - Analyst
JF - Analyst
SN - 0003-2654
IS - 9
ER -