Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Innate DNA sensing moves to the nucleus
AU - Unterholzner, Leonie
AU - Bowie, Andrew G.
N1 - Copyright © 2011 Elsevier Inc. All rights reserved.
PY - 2011/5/19
Y1 - 2011/5/19
N2 - It has been assumed that cells distinguish viral from cellular DNA due to the former's presence in the cytosol. However, in this issue, Kerur et al. (2011) propose that the DNA genome of Kaposi's sarcoma-associated herpesvirus (KSHV) is recognized inside the nucleus by the DNA sensor IFI16, leading inflammasome activation.
AB - It has been assumed that cells distinguish viral from cellular DNA due to the former's presence in the cytosol. However, in this issue, Kerur et al. (2011) propose that the DNA genome of Kaposi's sarcoma-associated herpesvirus (KSHV) is recognized inside the nucleus by the DNA sensor IFI16, leading inflammasome activation.
U2 - 10.1016/j.chom.2011.05.001
DO - 10.1016/j.chom.2011.05.001
M3 - Journal article
C2 - 21575905
VL - 9
SP - 351
EP - 353
JO - Cell Host and Microbe
JF - Cell Host and Microbe
SN - 1931-3128
IS - 5
ER -