Home > Research > Publications & Outputs > Psychological interventions for adults with bip...

Electronic data

  • Psychological_interventions_for_adults_with_bipolar_disorder

    Rights statement: This is an author-produced electronic version of an article accepted for publication in the British Journal of Psychiatry. The definitive publisher-authenticated version is available online at http://bjp.rcpsych.org

    Accepted author manuscript, 146 KB, PDF-document

    Available under license: CC BY-NC: Creative Commons Attribution-NonCommercial 4.0 International License

Links

Text available via DOI:

View graph of relations

Psychological interventions for adults with bipolar disorder: a systematic review and meta-analysis

Research output: Contribution to journalJournal article

Published
  • Matthijs Oud
  • Evan Mayo-Wilson
  • Ruth Braidwood
  • Peter Schulte
  • Steven Jones
  • Richard Morriss
  • Ralph Kupka
  • Pim Cuijpers
  • Tim Kendall
Close
<mark>Journal publication date</mark>03/2016
<mark>Journal</mark>British Journal of Psychiatry
Issue number3
Volume208
Number of pages10
Pages (from-to)213-222
Publication statusPublished
Early online date1/03/16
Original languageEnglish

Abstract

Background

Psychological interventions may be beneficial in bipolar disorder.

Aims

To evaluate the efficacy of psychological interventions for adults with bipolar disorder.

Method

A systematic review of randomised controlled trials was conducted. Outcomes were meta-analysed using RevMan and confidence assessed using the GRADE method.

Results

We included 55 trials with 6010 participants. Moderate-quality evidence associated individual psychological interventions with reduced relapses at post-treatment (risk ratio (RR) = 0.66, 95% CI 0.48–0.92) and follow-up (RR = 0.74, 95% CI 0.63–0.87), and collaborative care with a reduction in hospital admissions (RR = 0.68, 95% CI 0.49–0.94). Low-quality evidence associated group interventions with fewer depression relapses at post-treatment and follow-up, and family psychoeducation with reduced symptoms of depression and mania.

Conclusions

There is evidence that psychological interventions are effective for people with bipolar disorder. Much of the evidence was of low or very low quality thereby limiting our conclusions. Further research should identify the most effective (and cost-effective) interventions for each phase of this disorder.

Bibliographic note

This is an author-produced electronic version of an article accepted for publication in the British Journal of Psychiatry. The definitive publisher-authenticated version is available online at http://bjp.rcpsych.org