Rights statement: http://journals.cambridge.org/action/displayJournal?jid=HYG The final, definitive version of this article has been published in the Journal, Epidemiology and Infection, 138 (10), pp 1384-1390 2010, © 2010 Cambridge University Press.
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Research output: Contribution to Journal/Magazine › Journal article › peer-review
<mark>Journal publication date</mark> | 10/2010 |
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<mark>Journal</mark> | Epidemiology and Infection |
Issue number | 10 |
Volume | 138 |
Number of pages | 7 |
Pages (from-to) | 1384-1390 |
Publication Status | Published |
<mark>Original language</mark> | English |
A total of 969 isolates of Campylobacter jejuni originating in the Preston, Lancashire postcode district over a 3-year period were characterized using multi-locus sequence typing. Recently developed statistical methods and a genetic model were used to investigate temporal, spatial, spatio-temporal and genetic variation in human C. jejuni infections. The analysis of the data showed statistically significant seasonal variation, spatial clustering, small-scale spatio-temporal clustering and spatio-temporal interaction in the overall pattern of incidence, and spatial segregation in cases classified according to their most likely species-of-origin.