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Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery

Research output: Contribution to journalLiterature review

Published
  • Sofia Municoy
  • María Álvarez Echazú
  • Pablo Antezana
  • Juan Galdopórpora
  • Christian Olivetti
  • Andrea Mebert
  • María Foglia
  • María Tuttolomondo
  • Gisela Alvarez
  • John Hardy
  • Martin Desimone
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Article number4724
<mark>Journal publication date</mark>2/07/2020
<mark>Journal</mark>International Journal of Molecular Sciences
Issue number13
Volume21
Number of pages39
Publication statusPublished
Original languageEnglish

Abstract

Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions, structure, and/or dimensions. The specificity of stimuli response, and ability to respond to endogenous cues inherently present in living systems provide possibilities to develop novel tissue engineering and drug delivery strategies (for example materials composed of stimuli responsive polymers that self-assemble or undergo phase transitions or morphology transformations). Herein, smart materials as controlled drug release vehicles for tissue engineering are described, highlighting their potential for the delivery of precise quantities of drugs at specific locations and times promoting the controlled repair or remodeling of tissues.