Home > Research > Publications & Outputs > The melanocyte lineage in development and disease

Research

Links

Text available via DOI:

Keywords

View graph of relations

The melanocyte lineage in development and disease

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Published

Standard

The melanocyte lineage in development and disease. / Mort, Richard L.; Jackson, Ian J.; Patton, E. Elizabeth.
In: Development, Vol. 142, No. 4, 15.02.2015, p. 620-632.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Mort, RL, Jackson, IJ & Patton, EE 2015, 'The melanocyte lineage in development and disease', Development, vol. 142, no. 4, pp. 620-632. https://doi.org/10.1242/dev.106567

APA

Mort, R. L., Jackson, I. J., & Patton, E. E. (2015). The melanocyte lineage in development and disease. Development, 142(4), 620-632. https://doi.org/10.1242/dev.106567

Vancouver

Mort RL, Jackson IJ, Patton EE. The melanocyte lineage in development and disease. Development. 2015 Feb 15;142(4):620-632. Epub 2015 Feb 10. doi: 10.1242/dev.106567

Author

Mort, Richard L. ; Jackson, Ian J. ; Patton, E. Elizabeth. / The melanocyte lineage in development and disease. In: Development. 2015 ; Vol. 142, No. 4. pp. 620-632.

Bibtex

@article{6adc6f3193cd44e6a8672aa91901d2b9,
title = "The melanocyte lineage in development and disease",
abstract = "Melanocyte development provides an excellent model for studying more complex developmental processes. Melanocytes have an apparently simple aetiology, differentiating from the neural crest and migrating through the developing embryo to specific locations within the skin and hair follicles, and to other sites in the body. The study of pigmentation mutations in the mouse provided the initial key to identifying the genes and proteins involved in melanocyte development. In addition, work on chicken has provided important embryological and molecular insights, whereas studies in zebrafish have allowed live imaging as well as genetic and transgenic approaches. This cross-species approach is powerful and, as we review here, has resulted in a detailed understanding of melanocyte development and differentiation, melanocyte stem cells and the role of the melanocyte lineage in diseases such as melanoma.",
keywords = "Animals, Humans, Melanocytes, Melanoma, Microphthalmia-Associated Transcription Factor, Neural Crest, Stem Cells, Journal Article, Research Support, Non-U.S. Gov't, Review",
author = "Mort, {Richard L.} and Jackson, {Ian J.} and Patton, {E. Elizabeth}",
note = "{\textcopyright} 2015. Published by The Company of Biologists Ltd.",
year = "2015",
month = feb,
day = "15",
doi = "10.1242/dev.106567",
language = "English",
volume = "142",
pages = "620--632",
journal = "Development",
issn = "0950-1991",
publisher = "Company of Biologists Ltd",
number = "4",

}

RIS

TY - JOUR

T1 - The melanocyte lineage in development and disease

AU - Mort, Richard L.

AU - Jackson, Ian J.

AU - Patton, E. Elizabeth

N1 - © 2015. Published by The Company of Biologists Ltd.

PY - 2015/2/15

Y1 - 2015/2/15

N2 - Melanocyte development provides an excellent model for studying more complex developmental processes. Melanocytes have an apparently simple aetiology, differentiating from the neural crest and migrating through the developing embryo to specific locations within the skin and hair follicles, and to other sites in the body. The study of pigmentation mutations in the mouse provided the initial key to identifying the genes and proteins involved in melanocyte development. In addition, work on chicken has provided important embryological and molecular insights, whereas studies in zebrafish have allowed live imaging as well as genetic and transgenic approaches. This cross-species approach is powerful and, as we review here, has resulted in a detailed understanding of melanocyte development and differentiation, melanocyte stem cells and the role of the melanocyte lineage in diseases such as melanoma.

AB - Melanocyte development provides an excellent model for studying more complex developmental processes. Melanocytes have an apparently simple aetiology, differentiating from the neural crest and migrating through the developing embryo to specific locations within the skin and hair follicles, and to other sites in the body. The study of pigmentation mutations in the mouse provided the initial key to identifying the genes and proteins involved in melanocyte development. In addition, work on chicken has provided important embryological and molecular insights, whereas studies in zebrafish have allowed live imaging as well as genetic and transgenic approaches. This cross-species approach is powerful and, as we review here, has resulted in a detailed understanding of melanocyte development and differentiation, melanocyte stem cells and the role of the melanocyte lineage in diseases such as melanoma.

KW - Animals

KW - Humans

KW - Melanocytes

KW - Melanoma

KW - Microphthalmia-Associated Transcription Factor

KW - Neural Crest

KW - Stem Cells

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Review

U2 - 10.1242/dev.106567

DO - 10.1242/dev.106567

M3 - Journal article

C2 - 25670789

VL - 142

SP - 620

EP - 632

JO - Development

JF - Development

SN - 0950-1991

IS - 4

ER -