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Professor Christian Holscher

Formerly at Lancaster University

  1. Published

    Liraglutide protects against amyloid-β protein-induced impairment of spatial learning and memory in rats

    Han, W-N., Hölscher, C., Yuan, L., Yang, W., Wang, X-H., Wu, M-N. & Qi, J-S., 02/2013, In: Neurobiology of Aging. 34, 2, p. 576-588 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells

    Panagaki, T., Michael, M. & Hölscher, C., 23/11/2017, In: Scientific Reports. 7, 16 p., 16158.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Lixisenatide attenuates the detrimental effects of amyloid β protein on spatial working memory and hippocampal neurons in rats

    Cai, H-Y., Wang, Z-J., Holscher, C., Yuan, L., Zhang, J., Sun, P., Li, J., Yang, W., Wu, M-N. & Qi, J-S., 1/02/2017, In: Behavioural Brain Research. 318, p. 28-35 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Lixisenatide rescues spatial memory and synaptic plasticity from amyloid β protein-induced impairments in rats

    Cai, H-Y., Hölscher, C., Yue, X-H., Zhang, S-X., Wang, X-H., Qiao, F., Yang, W. & Qi, J-S., 26/09/2014, In: Neuroscience. 277, p. 6-13 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease

    McClean, P. L. & Holscher, C., 11/2014, In: Neuropharmacology. 86, p. 241-258 18 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Metabolic signatures of human Alzheimer's disease (AD): H-1 NMR analysis of the polar metabolome of post-mortem brain tissue

    Graham, S. F., Holscher, C. & Green, B. D., 08/2014, In: Metabolomics. 10, 4, p. 744-753 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Neural circuit interactions between the dorsal raphe nucleus and the lateral hypothalamus: an experimental and computational study

    Jalewa, J., Joshi, A., McGinnity, T. M., Prasad, G., Wong-Lin, K. & Hölscher, C., 6/02/2014, In: PLoS ONE. 9, 2, 16 p., e88003.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Neuroprotective and anti-apoptotic effects of Liraglutide on SH-SY5Y cells exposed to Methylglyoxal stress

    Sharma, M., Jalewa, J. & Hölscher, C., 02/2014, In: Journal of Neurochemistry. 128, 3, p. 459-471 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Neuroprotective effects of (Val8)GLP-1-Glu-PAL in the MPTP Parkinson's disease mouse model

    Zhang, Y., Chen, Y., Li, L. & Holscher, C., 15/10/2015, In: Behavioural Brain Research. 293, p. 107-113 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Neuroprotective effects of a GIP analogue in the MPTP Parkinson's disease mouse model

    Li, Y., Liu, W., Li, L. & Holscher, C., 02/2016, In: Neuropharmacology. 101, p. 255-263 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease

    Tai, J., Liu, W., Li, Y., Li, L. & Hölscher, C., 1/01/2018, In: Brain Research. 1678, p. 64-74 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease

    Liu, W., Li, Y., Jalewa, J., Saunders-Wood, T., Li, L. & Hölscher, C., 2015, In: European Journal of Pharmacology. 765, p. 284-290 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Neuroprotective effects of D-Ala2GIP on Alzheimer’s disease biomarkers in an APP/PS1 mouse model

    Faivre, E. & Holscher, C., 19/04/2013, In: Alzheimer's Research and Therapy. 5, p. 20-29 10 p., 20.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Neuroprotective effects of geniposide in the MPTP mouse model of Parkinson's disease

    Chen, Y., Zhang, Y., Li, L. & Holscher, C., 5/12/2015, In: European Journal of Pharmacology. 768, p. 21-27 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Neuroprotective effects of geniposide on Alzheimer's disease pathology

    Liu, W., Li, G., Holscher, C. & Li, L., 08/2015, In: Reviews in the Neurosciences. 26, 4, p. 371-383 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Neuroprotective effects of glucose-dependent insulinotropic polypeptide in Alzheimer's disease

    Ji, C., Xue, G-F., Li, G., Li, D. & Holscher, C., 01/2016, In: Reviews in the Neurosciences. 27, 1, p. 61-70 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

    Liu, W., Jalewa, J., Sharma, M., Li, G., Li, L. & Holscher, C., 10/09/2015, In: Neuroscience. 303, p. 42-50 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model

    Zhang, L., Zhang, L., Li, L. & Hölscher, C., 10/2018, In: Neuropeptides. 71, p. 70-80 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Neuroprotective role of (Val8)GLP-1-Glu-PAL in an in vitro model of Parkinson’s disease

    Li, L., Liu, K., Holscher, C., Li, G. & Liu, Y-Z., 2016, In: Neural Regeneration Research. 11, 2, p. 326-331 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    New animal models of Alzheimer's disease that display insulin desensitization in the brain

    Gao, C., Liu, Y., Li, L. & Hölscher, C., 12/2013, In: Reviews in the Neurosciences. 24, 6, p. 607-615 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Novel dual GLP-1/GIP receptor agonists show neuroprotective effects in Alzheimer's and Parkinson's disease models

    Hölscher, C., 1/07/2018, In: Neuropharmacology. 136, Part B, p. 251-259 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain

    Hamilton, A., Patterson, S., Porter, D., Gault, V. A. & Hölscher, C., 04/2011, In: Journal of Neuroscience Research. 89, 4, p. 481-489 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Novel incretin analogues improve autophagy and protect from mitochondrial stress induced by rotenone in SH-SY5Y cells

    Jalewa, J., Sharma, M. K. & Holscher, C., 10/2016, In: Journal of Neurochemistry. 139, 1, p. 55-67 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Peptide drugs that have been developed to treat type 2 diabetes show neuroprotective effects

    Holscher, C., 06/2014, In: Regulatory Peptides. 192-193, p. 55-56 2 p.

    Research output: Contribution to Journal/MagazineEditorialpeer-review

  25. Published

    Pharmacological inhibition of CSF1R blocks microglial proliferation and prevents the progression of Alzheimer's-like pathology

    Olmos-Alonso, A., Schetters, S. T., Sri, S., Askew, K., Vargas-Caballero, M., Holscher, C., Perry, V. H. & Gomez-Nicola, D., 08/2015, In: Glia. 63, Suppl. 1, p. E346-E347 2 p.

    Research output: Contribution to Journal/MagazineMeeting abstractpeer-review

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