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Professor David Middleton

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  1. Published

    19F Solid-State NMR and Vibrational Raman Characterization of Corticosteroid Drug-Lipid Membrane Interactions

    Mapley, B., Townsend, D., Griffin, J., Ashton, L. & Middleton, D., 15/11/2021, In: ChemPlusChem. 86, 11, p. 1517-1523 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    A study of the membrane association and regulatory effect of the phospholemman cytoplasmic domain

    Hughes, E., Whittaker, C. A. P., Barsukov, I. L., Esmann, M. & Middleton, D. A., 04/2011, In: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1808, 4, p. 1021-31 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. E-pub ahead of print

    Aggregation Kinetics and Filament Structure of a Tau Fragment Are Influenced by the Sulfation Pattern of the Cofactor Heparin

    Townsend, D., Fullwood, N., Yates, E. & Middleton, D., 21/09/2020, (E-pub ahead of print) In: Biochemistry.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Amyloid-derived peptide forms self-assembled monolayers on gold nanoparticle with a curvature-dependent β-sheet structure

    Shaw, C. P., Middleton, D. A., Volk, M. & Lévy, R., 28/02/2012, In: ACS Nano. 6, 2, p. 1416-26 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Forthcoming

    Analysis of the orientation of cholesterol in high-density lipoprotein nanodiscs using solid-state NMR

    Lau, S. & Middleton, D., 7/09/2022, (Accepted/In press) In: Physical Chemistry Chemical Physics.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Atomic details of the interactions of Glycosaminoglycans with amyloid-β fibrils

    Stewart, K., Hughes, E., Yates, E., Akien, G. R., Huang, T-Y., Lima, M., Rudd, T., Guerrini, M., Hung, S-C., Radford, S. & Middleton, D. A., 13/07/2016, In: Journal of the American Chemical Society. 138, 27, p. 8328-8331 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Average orientation of a fluoroaromatic molecule in lipid bilayers from DFT-informed NMR measurements of 1H-19F dipolar couplings

    Hughes, E., Griffin, J. M., Coogan, M. P. & Middleton, D. A., 21/07/2018, In: Physical Chemistry Chemical Physics. 20, 27, p. 18207-18215 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. E-pub ahead of print

    Circular dichroism spectroscopy identifies the β-adrenoceptor agonist salbutamol as a direct inhibitor of tau filament formation in vitro.

    Middleton, D., Townsend, D., Hughes, E., Fullwood, N., Siligardi, G., Hussain, R. & Mala, B., 10/06/2020, (E-pub ahead of print) In: ACS Chemical Neuroscience.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Comparison of aggregation enhancement and inhibition as strategies for reducing the cytotoxicity of the aortic amyloid polypeptide medin

    Madine, J. & Middleton, D. A., 08/2010, In: June 2002. ISSN 1460-4582. 39, 9, p. 1281-8 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Comparison of the structure and function of phospholamban and the Arginine-14 deficient mutant associated with dilated cardiomyopathy

    Hughes, E. & Middleton, D. A., 16/09/2014, In: PLoS ONE. 9, 9, 10 p., 106746.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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