Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery

Hatano, T., Palani, S., Papatziamou, D., Salzer, R., Souza, D. P., Tamarit, D., Makwana, M., Potter, A., Haig, A., Xu, W., Townsend, D., Rochester, D., Bellini, D., Hussain, H. M. A., Ettema, T. J. G., Löwe, J., Baum, B., Robinson, N. P. & Balasubramanian, M., 13/06/2022, In: Nature Communications. 13, 1, 16 p., 3398.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

19F Solid-State NMR and Vibrational Raman Characterization of Corticosteroid Drug-Lipid Membrane Interactions

Mapley, B., Townsend, D., Griffin, J., Ashton, L. & Middleton, D., 15/11/2021, In: ChemPlusChem. 86, 11, p. 1517-1523 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Characterisation of the Ubiquitin-ESCRT pathway in Asgard archaea sheds new light on origins of membrane trafficking in eukaryotes

Hatano, T., Palani, S., Papatziamou, D., Souza, D., Salzer, R., Tamarit, D., Makwana, M., Potter, A., Haig, A., Xu, W., Townsend, D., Rochester, D., Bellini, D., Hussain, H., Ettema, T., Löwe, J., Baum, B., Robinson, N. & Balasubramanian, M., 17/08/2021, In: Biorxiv. 27 p.

Research output: Contribution to Journal/Magazine › Journal article

Potential for Chemistry in Multidisciplinary, Interdisciplinary, and Transdisciplinary Teaching Activities in Higher Education

Hardy, J., Sdepanian, S., Stowell, A., Aljohani, A., Allen, M., Anwar, A., Barton, D., Baum, J., Bird, D., Blaney, A., Brewster, L., Cheneler, D., Efremova, O., Entwistle, M., Esfahani, R., Firlak, M., Foito, A., Forciniti, L., Geissler, S., Guo, F., & 19 othersHathout, R., Jiang, R., Kevin, P., Leese, D., Low, W. L., Mayes, S., Mozafari, M., Murphy, S., Nguyen, H., Ntola, C., Okafo, G., Partington, A., Prescott, T., Price, S., Soliman, S., Sutar, P., Townsend, D., Trotter, P. & Wright, K., 4/03/2021, In: Journal of Chemical Education. 98, 4, p. 1124–1145 22 p.

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Raman Spectroscopy with 2D Perturbation Correlation Moving Windows for the Characterization of Heparin–Amyloid Interactions

Townsend, D., Middleton, D. & Ashton, L., 31/10/2020, In: Analytical Chemistry. 92, 20, p. 13822–13828 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Aggregation Kinetics and Filament Structure of a Tau Fragment Are Influenced by the Sulfation Pattern of the Cofactor Heparin

Townsend, D., Fullwood, N., Yates, E. & Middleton, D., 21/09/2020, (E-pub ahead of print) In: Biochemistry.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Circular dichroism spectroscopy identifies the β-adrenoceptor agonist salbutamol as a direct inhibitor of tau filament formation in vitro.

Middleton, D., Townsend, D., Hughes, E., Fullwood, N., Siligardi, G., Hussain, R. & Mala, B., 10/06/2020, (E-pub ahead of print) In: ACS Chemical Neuroscience.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Electroactive Silk Fibroin Films for Electrochemically Enhanced Delivery of Drugs

Mousavi, S., Harper, G., Municoy, S., Ashton, M., Townsend, D., Alsharif, G., Oikonomou, V., Au-Yong, S., Murdock, B., Akien, G., Halcovitch, N., Baldock, S., Fazilati, M., Kolosov, O., Robinson, B., Desimone, M. & Hardy, J., 1/06/2020, In: Macromolecular Materials and Engineering. 305, 6, 7 p., 2000130.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Orientation of a Diagnostic Ligand Bound to Macroscopically Aligned Amyloid-β Fibrils Determined by Solid-State NMR

Townsend, D. J., Hughes, E., Stewart, K., Griffin, J. M., Radford, S. & Middleton, D. A., 15/11/2018, In: The Journal of Physical Chemistry Letters. 9, 22, p. 6611–6615 5 p.

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Epigallocatechin-3-gallate remodels apolipoprotein A-I amyloid fibrils into soluble oligomers in the presence of heparin

Townsend, D., Hughes, E., Akien, G., Stewart, K. L., Radford, S. E., Rochester, D. & Middleton, D. A., 17/08/2018, In: Journal of Biological Chemistry. 293, 33, p. 12877-12893 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Heparin and methionine oxidation promote the formation of apolipoprotein A-I amyloid comprising α-helical and β-sheet structures.

Townsend, D. J., Hughes, E., Hussain, R., Siligardi, G., Baldock, S. J., Madine, J. & Middleton, D. A., 21/03/2017, In: Biochemistry. 56, 11, p. 1632-1644 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review